Early detection and quantification of lamivudine-resistant hepatitis B virus mutants by fluorescent biprobe hybridization assay in lamivudine-treated patients

Journal of Gastroenterology

Volumn 41, Issue 7, 2006, Pages 693-701

  Umeoka, Fumi ^a   Iwasaki, Yoshiaki ^a   Matsumura, Masayuki ^b   Takaki, Akinobu ^a   Kobashi, Haruhiko ^a   Tatsukawa, Masashi ^a   Shiraha, Hidenori ^a   Fujioka, Shin Ichi ^a   Sakaguchi, Kohsaku ^a   Shiratori, Yasushi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b INSTITUTE FOR ADULT DISEASES   (Japan)

Author keywords

Fluorescent biprobe hybridization assay; Hepatitis B virus; Lamivudine; Mutation

Indexed keywords

DNA POLYMERASE; LAMIVUDINE; PLASMID DNA; VIRUS DNA;

ADULT; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; DISEASE COURSE; DNA SEQUENCE; FEMALE; FLUORESCENCE; FOLLOW UP; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HYBRIDIZATION; MALE; MOLECULAR PROBE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; VIRUS MUTANT; VIRUS RESISTANCE; WILD TYPE;

ADULT; ANTIVIRAL AGENTS; DNA PROBES; DNA-DIRECTED DNA POLYMERASE; DRUG RESISTANCE, VIRAL; FEMALE; FLUOROMETRY; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; LAMIVUDINE; MALE; MIDDLE AGED; MUTATION; NUCLEIC ACID HYBRIDIZATION; SENSITIVITY AND SPECIFICITY; TRANSITION TEMPERATURE;

EID: 33747888329     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-006-1834-x     Document Type: Article

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