Use of real-time PCR and fluorimetry to detect lamivudine resistance- associated mutations in hepatitis B virus

Antimicrobial Agents and Chemotherapy

Volumn 43, Issue 7, 1999, Pages 1600-1608

  Cane, Patricia A ^a   Cook, Pamela ^a   Ratcliffe, Daina ^a   Mutimer, David ^a   Pillay, Deenan ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; LAMIVUDINE;

ARTICLE; CLINICAL ARTICLE; DNA SEQUENCE; FLUOROMETRY; GENE MUTATION; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; MELTING POINT; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; VIRUS DETECTION; VIRUS GENE; VIRUS RESISTANCE;

EID: 0032773180     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.7.1600     Document Type: Article

References (14)

1. Allen, M. I., M. Deslauriers, C. W. Andrews, G. A. Tipples, K. A. Walters, D. L. J. Tyrrell, N. Brown, and L. D. Condreay. 1998. Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Hepatology 27:1670-1677.
2. Aye, T. T., A. Bartholomeusz, T. Shaw, S. Bowden, A. Breschkin, J. McMillan, P. Angus, and S. Locarnini. 1997. Hepatitis B virus polymerase mutations during antiviral therapy in a patient following liver transplantation. J. Hepatol. 26:1148-1153.
3. Bartholomew, M. M., R. W. Jansen, L. J. Jeffers, K. R. Reddy, L. C. Johnson, H. Bunzendahl, L. D. Condreay, A. G. Tzakis, E. R. Schiff, and N. A. Brown. 1997. Hepatitis-B virus resistance to lamivudine given for recurrent infection after orthotopic liver transplantation. Lancet 349:20-22.
4. Burroughs, N. J., D. A. Rand, D. Pillay, E. Elias, and D. Mutimer. 1998. The consequences of quasispecies heterogeneity and within-host ecology for antiviral therapy of hepatitis B virus, p. 335-343. In R. F. Schinazi, J. P. Sommadossi, and H. Thomas (ed.), Therapies for viral hepatitis. International Medical Press.
5. Buti, M., R. Jardi, M. Cotrina, F. Rodriguez-Frias, R. Esteban, and J. Guardia. 1998. Transient emergence of hepatitis B variants in a patient with chronic hepatitis B resistant to lamivudine. J. Hepatol. 28:510-513.
6. Cane, P. A., D. Mutimer, D. Ratcliffe, P. Cook, G. Beards, E. Elias, and D. Pillay. 1999. Analysis of HBV quasispecies changes during emergence and reversion of lamivudine resistance in liver transplantation. Antiviral Ther. 4:7-14.
7. Chayama, K., Y. Suzuki, M. Kobayashi, M. Kobayashi, A. Tsubota, M. Hashimoto, Y. Miyano, H. Koike, M. Kobayashi, I. Koida, Y. Arase, S. Saitoh, N. Murashima, K. Ikeda, and H. Kumada. 1998. Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy. Hepatology 27:1711-1716.
8. Honkoop, P., H. G. Niesters, R. A. deMan, A. D. Osterhaus, and S. W. Schalm. 1997. Lamivudine resistance in immunocompetent chronic hepatitis B. Incidence and patterns. J. Hepatol. 26:1393-1395.
9. Lai, C.-L., R.-N. Chien, N. W. Y. Leung, T.-T. Chang, R. Guan, D.-I. Tai, K.-Y. Ng, P.-C. Wu, J. C. Dent, J. Barber, S. L. Stephenson, and D. F. Gray. 1998. A one-year trial of lamivudine for chronic hepatitis B. N. Engl. J. Med. 339:61-68.
10. Ling, R., D. Mutimer, M. Ahmed, E. H. Boxall, E. Elias, G. M. Dusheiko, and T. J. Harrison. 1996. Selection of mutations in the hepatitis B virus polymerase during therapy of transplant recipients with lamivudine. Hepatology 24:711-713.
11. Nauomov, N. V., S. Chokshi, H. M. Smith, and R. Williams. 1996. Emergence and characterisation of lamivudine-resistant hepatitis B virus variant. Hepatology 24:282A.
12. Pillay, D., A. Bartholomeusz, P. A. Cane, D. Mutimer, R. F. Schinazi, and S. Locarnini. 1998. Mutations in the hepatitis B virus DNA polymerase associated with antiviral resistance. Antiviral News 6:167-169.
13. Tipples, G. A., M. M. Ma, K. P. Fischer, V. G. Bain, N. M. Kneteman, and D. L. Tyrrell. 1996. Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivudine in vivo. Hepatology 24:714-717.
14. Woo, T. H. S., B. K. C. Patel, L. D. Smythe, M. L. Symonds, M. A. Norris, and M. F. Dohnt. 1997. Identification of pathogenic Leptospira genospecies by continuous monitoring of fluorogenic hybridization probes during rapid-cycle PCR. J. Clin. Microbiol. 35:3140-3146.