The changing role of NMR spectroscopy in off-line impurity identification: A conceptual view

TrAC - Trends in Analytical Chemistry

Volumn 25, Issue 8, 2006, Pages 806-820

  Szántay Jr , Csaba ^a   Béni, Zoltán ^a   Balogh, Gábor ^a   Gáti, Tamás ^a  

^a GEDEON RICHTER LTD   (Hungary)

Author keywords

Cold probe; Impurity; NMR; Nuclear magnetic resonance; Sensitivity; Structure determination

Indexed keywords

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROBES; STRUCTURAL ANALYSIS; TRACE ANALYSIS;

COLD PROBES; STRUCTURE DETERMINATION; TRACE IMPURITIES;

IMPURITIES;

STEROID; VINBLASTINE; VINLEUROSINE;

ANALOG DIGITAL CONVERTER; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG IMPURITY; DRUG STRUCTURE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RADIOFREQUENCY; SENSITIVITY AND SPECIFICITY; SIGNAL NOISE RATIO; SIGNAL PROCESSING; SOLID PHASE EXTRACTION; STEREOCHEMISTRY; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 33747875755     PISSN: 01659936     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trac.2006.06.006     Document Type: Article

References (37)

1. Griffin J.L. Drug Disc. Today 1 (2004) 463
2. van der Greef J., Stroobant P., and van der Heijden R. Curr. Op. Chem. Biol. 8 (2004) 559
3. Pelczer I. Curr. Op. Drug. Disc. Dev. 8 (2005) 127
4. Winter W., Deubner R., and Holzgrabe U. J. Pharm. Biomed. Anal. 38 (2005) 833
5. Lehr G.J., Barry T.L., Petzinger G., Hanna G.M., and Zito S.W. J. Pharm. Biomed. Anal. 19 (1999) 373
6. Holzgrabe U., Deubner R., Schollmayer C., and Waibel B. J. Pharm. Biomed. Anal. 38 (2005) 806
7. Szántay Jr. Cs. Trends Anal. Chem. 11 (1992) 332
8. Traficante D.D. Concepts Magn. Reson. 4 (1992) 153
9. Holzgrabe U. J. Pharm. Biomed. Anal. 38 (2005) 7
10. Szántay Jr. Cs., and Demeter A. In: Görög S. (Ed). Identification and Determination of Impurities in Drugs (1999), Elsevier, Amsterdam, The Netherlands 109-145
11. Purcell E.M., Torrey H.G., and Pound R.V. Phys. Rev. 69 (1946) 37
12. Bloch F., Hansen W., and Packard M.E. Phys. Rev. 69 (1946) 127
13. Bloch F. Phys. Rev. 70 (1946) 460
14. Duddeck H., Dietrich W., and Tóth G. Structure Elucidation by Modern NMR (1998), Springer, Darmstadt, Germany
15. Berger S., and Braun S. 200 and More NMR Experiments: A Practical Course (2004), Wiley, New York, USA
16. Hore P.J., Jones J.A., and Wimperis S. NMR: the Toolkit (2000), Oxford University Press, Oxford, UK
17. Lacey M.E., Subramanian R., Olson D.L., Webb A.G., and Sweedler J. Chem. Rev. 99 (1999) 3133
18. Olson D.L., Lacey M.E., Webb A.G., and Sweedler J. Anal. Chem. 71 (1999) 3070
19. Webb A.G. J. Pharm. Biomed. Anal. 38 (2005) 892
20. Subramanian R., Lam M.M., and Webb A.G. J. Magn. Reson. 133 (1998) 227
21. Subramanian R., and Webb A.G. Anal. Chem. 70 (1998) 2454
22. D.L. Olson, T.L. Peck, A.G. Webb, R.L. Magin, J.V. Sweedler, Science (Washington, DC) 270 (1995) 1970.
23. Crouch R.C., and Martin G.E. J. Nat. Prod. 55 (1992) 1343
24. Malz F., and Jancke H. J. Pharm. Biomed. Anal. 38 (2005) 813
25. Bodurka J., Ledden P.J., van Gelderen P., Chu R., de Zwart J.A., Morris D., and Duyn J.H. Magn. Reson. Med. 51 (2004) 165
26. Pérez P., and Santos A. Med. Eng. Phys. 26 (2004) 523
27. Trippleton M.J., and Keeler J. Angew. Chem., Int. Ed. Engl. 43 (2003) 3938
28. Freeman R., and Kupce E. Concepts Magn. Reson. 23A (2004) 63
29. Shrot Y., Shapira B., and Frydman L. J. Magn. Reson. 171 (2004) 163
30. In: Albert K. (Ed). On-line LC-NMR and Related Techniques (2002), Wiley, Chichester, West Sussex, UK
31. Webb A.G. Magn. Reson. Chem. 43 (2005) 688
32. Sherman G.J., and Jones I.C. Magn. Reson. Chem. 41 (2003) 448
33. Elipe M.V.S. Anal. Chim. Acta 497 (2003) 1
34. Halmos Zs., Szántay Jr. Cs., Brlik J., Csehi A., Varga K., Horváth P., Kislaki M., Domány Gy., Nemes A., and Görög S. J. Pharm. Biomed. Anal. 15 (1996) 1
35. Szántay Jr. Cs., Bihari M., Brlik J., Csehi A., Kassai A., and Aranyi A. Acta Pharm. Hung. 64 (1994) 105
36. Balogh G., Csizér E., Ferenczy Gy., Halmos Zs., Herényi B., Horváth P., Laukó A., and Görög S. Pharm. Res. 12 (1995) 295
37. Sandvoss M., Bardlsey B., Beck T.L., Lee-Smith E., North S.E., Moore P.J., Edwards A.J., and Smith R.J. Magn. Reson. Chem. 43 (2005) 762