메뉴 건너뛰기




Volumn 173, Issue 4, 2006, Pages 1909-1917

Using substrate-binding variants of the cAMP-dependent protein kinase to identify novel targets and a kinase domain important for substrate interactions in Saccharomyces cerevisiae

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE;

EID: 33747859628     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.106.059238     Document Type: Article
Times cited : (50)

References (49)
  • 1
    • 0035413606 scopus 로고    scopus 로고
    • Kinetic and catalytic mechanisms of protein kinases
    • ADAMS, J. A., 2001 Kinetic and catalytic mechanisms of protein kinases. Chem. Rev. 101: 2271-2290.
    • (2001) Chem. Rev. , vol.101 , pp. 2271-2290
    • Adams, J.A.1
  • 2
    • 14844307038 scopus 로고    scopus 로고
    • Protein kinase A as a therapeutic target for memory disorders: Rationale and challenges
    • ARNSTEN, A. F., B. P. RAMOS, S. G. BIRNBAUM and J. R. TAYLOR, 2005 Protein kinase A as a therapeutic target for memory disorders: rationale and challenges. Trends Mol. Med. 11: 121-128.
    • (2005) Trends Mol. Med. , vol.11 , pp. 121-128
    • Arnsten, A.F.1    Ramos, B.P.2    Birnbaum, S.G.3    Taylor, J.R.4
  • 4
    • 0026051160 scopus 로고
    • RAS genes in Saccharomyces cerevisiae: Signal transduction in search of a pathway
    • BROACH, J. R., 1991 RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathway. Trends Genet. 7: 28-33.
    • (1991) Trends Genet. , vol.7 , pp. 28-33
    • Broach, J.R.1
  • 5
    • 0037016749 scopus 로고    scopus 로고
    • The C terminus of the Vps34p phosphoinositide 3-kinase is necessary and sufficient for the interaction with the Vps15p protein kinase
    • BUDOVSKAYA, Y. V., H. HAMA, D. B. DEWALD and P. K. HERMAN, 2002 The C terminus of the Vps34p phosphoinositide 3-kinase is necessary and sufficient for the interaction with the Vps15p protein kinase. J. Biol. Chem. 277: 287-294.
    • (2002) J. Biol. Chem. , vol.277 , pp. 287-294
    • Budovskaya, Y.V.1    Hama, H.2    DeWald, D.B.3    Herman, P.K.4
  • 6
    • 2442645050 scopus 로고    scopus 로고
    • The Ras/cAMP-dependent protein kinase signaling pathway regulates an early step of the autophagy process in Saccharomyces cerevisiae
    • BUDOVSKAYA, Y. V., J. S. STEPHAN, F. REGGIORI, D. J. KLIONSKY and P. K. HERMAN, 2004 The Ras/cAMP-dependent protein kinase signaling pathway regulates an early step of the autophagy process in Saccharomyces cerevisiae. J. Biol. Chem. 279: 20663-20671.
    • (2004) J. Biol. Chem. , vol.279 , pp. 20663-20671
    • Budovskaya, Y.V.1    Stephan, J.S.2    Reggiori, F.3    Klionsky, D.J.4    Herman, P.K.5
  • 7
    • 25444459688 scopus 로고    scopus 로고
    • An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase
    • BUDOVSKAYA, Y. V., J. S. STEPHAN, S. J. DEMINOFF and P. K. HERMAN, 2005 An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 102: 13933-13938.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 13933-13938
    • Budovskaya, Y.V.1    Stephan, J.S.2    Deminoff, S.J.3    Herman, P.K.4
  • 8
    • 0035156558 scopus 로고    scopus 로고
    • The rye mutants identify a role for Ssn/Srb proteins of the RNA polymerase II holoenzyme during stationary phase entry in Saccharomyces cerevisiae
    • CHANG, Y. W., S. C. HOWARD, Y. V. BUDOVSKAYA, J. RINE and P. K. HERMAN, 2001 The rye mutants identify a role for Ssn/Srb proteins of the RNA polymerase II holoenzyme during stationary phase entry in Saccharomyces cerevisiae. Genetics 157: 17-26.
    • (2001) Genetics , vol.157 , pp. 17-26
    • Chang, Y.W.1    Howard, S.C.2    Budovskaya, Y.V.3    Rine, J.4    Herman, P.K.5
  • 9
    • 3042760385 scopus 로고    scopus 로고
    • The Ras/PKA signaling pathway directly targets the Srb9 protein, a component of the general RNA polymerase II transcription apparatus
    • CHANG, Y. W., S. C. HOWARD and P. K. HERMAN, 2004 The Ras/PKA signaling pathway directly targets the Srb9 protein, a component of the general RNA polymerase II transcription apparatus. Mol. Cell. 15: 107-116.
    • (2004) Mol. Cell , vol.15 , pp. 107-116
    • Chang, Y.W.1    Howard, S.C.2    Herman, P.K.3
  • 10
    • 0036527429 scopus 로고    scopus 로고
    • Protein kinases - The major drug targets of the twenty-first century?
    • COHEN, P., 2002 Protein kinases - The major drug targets of the twenty-first century? Nat. Rev. Drug Discov. 1: 309-315.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 309-315
    • Cohen, P.1
  • 11
    • 0032546925 scopus 로고    scopus 로고
    • The vesicle transport protein Vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner
    • GERHARDT, B., T. J. KORDAS, C. M. THOMPSON, P. PATEL and T. VIDA, 1998 The vesicle transport protein Vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner. J. Biol. Chem. 273: 15818-15829.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15818-15829
    • Gerhardt, B.1    Kordas, T.J.2    Thompson, C.M.3    Patel, P.4    Vida, T.5
  • 12
    • 0025834693 scopus 로고
    • Identification of electrostatic interactions that determine the phosphorylation site specificity of the cAMP-dependent protein kinase
    • GIBBS, C. S., and M. J. ZOLLER, 1991a Identification of electrostatic interactions that determine the phosphorylation site specificity of the cAMP-dependent protein kinase. Biochemistry 30: 5329-5334.
    • (1991) Biochemistry , vol.30 , pp. 5329-5334
    • Gibbs, C.S.1    Zoller, M.J.2
  • 13
    • 0025739664 scopus 로고
    • Rational scanning mutagenesis of a protein kinase identifies functional regions involved in catalysis and substrate interactions
    • GIBBS, C. S., and M. J. ZOLLER, 1991b Rational scanning mutagenesis of a protein kinase identifies functional regions involved in catalysis and substrate interactions. J. Biol. Chem. 266: 8923-8931.
    • (1991) J. Biol. Chem. , vol.266 , pp. 8923-8931
    • Gibbs, C.S.1    Zoller, M.J.2
  • 14
    • 0027054644 scopus 로고
    • Phosphorylation of the S. cerevisiae Cdc25 in response to glucose results in its dissociation from Ras
    • GROSS, E., D. GOLDBERG and A. LEVITZKI, 1992 Phosphorylation of the S. cerevisiae Cdc25 in response to glucose results in its dissociation from Ras. Nature 360: 762-765.
    • (1992) Nature , vol.360 , pp. 762-765
    • Gross, E.1    Goldberg, D.2    Levitzki, A.3
  • 15
    • 0038339419 scopus 로고    scopus 로고
    • Genomic analysis of the eukaryotic protein kinase superfamily: A perspective
    • HANKS, S. K., 2003 Genomic analysis of the eukaryotic protein kinase superfamily: a perspective. Genome Biol. 4: 111.
    • (2003) Genome Biol. , vol.4 , pp. 111
    • Hanks, S.K.1
  • 16
    • 0029020282 scopus 로고
    • Protein kinases 6. The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
    • HANKS, S. K., and T. HUNTER, 1995 Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J. 9: 576-596.
    • (1995) FASEB J. , vol.9 , pp. 576-596
    • Hanks, S.K.1    Hunter, T.2
  • 18
    • 0036897875 scopus 로고    scopus 로고
    • Stationary phase in yeast
    • HERMAN, P. K., 2002 Stationary phase in yeast. Curr. Opin. Microbiol. 5: 602-607.
    • (2002) Curr. Opin. Microbiol. , vol.5 , pp. 602-607
    • Herman, P.K.1
  • 19
    • 0030670625 scopus 로고    scopus 로고
    • Yeast spore germination: A requirement for Ras protein activity during re-entry into the cell cycle
    • HERMAN, P. K., and J. RINE, 1997 Yeast spore germination: a requirement for Ras protein activity during re-entry into the cell cycle. EMBO J. 16: 6171-6181.
    • (1997) EMBO J. , vol.16 , pp. 6171-6181
    • Herman, P.K.1    Rine, J.2
  • 20
    • 0037205450 scopus 로고    scopus 로고
    • The C-terminal domain of the largest subunit of RNA polymerase II is required for stationary phase entry and functionally interacts with the Ras/PKA signaling pathway
    • HOWARD, S. C., Y. V. BUDOVSKAYA, Y. W. CHANG and P. K. HERMAN, 2002 The C-terminal domain of the largest subunit of RNA polymerase II is required for stationary phase entry and functionally interacts with the Ras/PKA signaling pathway. J. Biol. Chem. 277: 19488-19497.
    • (2002) J. Biol. Chem. , vol.277 , pp. 19488-19497
    • Howard, S.C.1    Budovskaya, Y.V.2    Chang, Y.W.3    Herman, P.K.4
  • 21
    • 0345730820 scopus 로고    scopus 로고
    • The Ras/PKA signaling pathway may control RNA polymerase II elongation via the Spt4p/Spt5p complex in Saccharomyces cerevisiae
    • HOWARD, S. C., A. HESTER and P. K. HERMAN, 2003 The Ras/PKA signaling pathway may control RNA polymerase II elongation via the Spt4p/Spt5p complex in Saccharomyces cerevisiae. Genetics 165: 1059-1070.
    • (2003) Genetics , vol.165 , pp. 1059-1070
    • Howard, S.C.1    Hester, A.2    Herman, P.K.3
  • 22
    • 31044438337 scopus 로고    scopus 로고
    • Increased phosphoglucomutase activity suppresses the galactose growth defect associated with elevated levels of Ras signaling in S. cerevisiae
    • HOWARD, S. C., S. J. DEMINOFF and P. K. HERMAN, 2006 Increased phosphoglucomutase activity suppresses the galactose growth defect associated with elevated levels of Ras signaling in S. cerevisiae. Curr. Genet. 49: 1-6.
    • (2006) Curr. Genet. , vol.49 , pp. 1-6
    • Howard, S.C.1    Deminoff, S.J.2    Herman, P.K.3
  • 23
    • 0034614490 scopus 로고    scopus 로고
    • Signaling - 2000 And beyond
    • HUNTER, T., 2000 Signaling - 2000 and beyond. Cell 100: 113-127.
    • (2000) Cell , vol.100 , pp. 113-127
    • Hunter, T.1
  • 24
    • 0030455820 scopus 로고    scopus 로고
    • Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
    • JAMES, P., J. HALLADAY and E. A. CRAIG, 1996 Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144: 1425-1436.
    • (1996) Genetics , vol.144 , pp. 1425-1436
    • James, P.1    Halladay, J.2    Craig, E.A.3
  • 26
    • 18744415995 scopus 로고    scopus 로고
    • Kinomics: Methods for deciphering the kinome
    • JOHNSON, S. A., and T. HUNTER, 2005 Kinomics: methods for deciphering the kinome. Nat. Methods 2: 17-25.
    • (2005) Nat. Methods , vol.2 , pp. 17-25
    • Johnson, S.A.1    Hunter, T.2
  • 28
    • 0028251408 scopus 로고
    • Substrate and pseudosubstrate interactions with protein kinases: Determinants of specificity
    • KEMP, B. E., M. W. PARKER, S. HU, T. TIGANIS and C. HOUSE, 1994 Substrate and pseudosubstrate interactions with protein kinases: determinants of specificity. Trends Biochem. Sci. 19: 440-444.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 440-444
    • Kemp, B.E.1    Parker, M.W.2    Hu, S.3    Tiganis, T.4    House, C.5
  • 29
    • 2642699794 scopus 로고
    • Rapid and efficient site-specific mutagenesis without phenotypic selection
    • KUNKEL, T. A., 1985 Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. USA 82: 488-492.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 488-492
    • Kunkel, T.A.1
  • 30
    • 18744429842 scopus 로고    scopus 로고
    • Hitting the target: Emerging technologies in the search for kinase substrates
    • MANNING, B. D., and L. C. CANTLEY, 2002 Hitting the target: emerging technologies in the search for kinase substrates. Sci. STKE 162: 1-4.
    • (2002) Sci. STKE , vol.162 , pp. 1-4
    • Manning, B.D.1    Cantley, L.C.2
  • 32
    • 0026675779 scopus 로고
    • Yeast SKO1 gene encodes a bZIP protein that binds to the CRE motif and acts as a repressor of transcription
    • NEHLIN, J. O., M. CARLBERG and H. RONNE, 1992 Yeast SKO1 gene encodes a bZIP protein that binds to the CRE motif and acts as a repressor of transcription. Nucleic Acids Res. 20: 5271-5278.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 5271-5278
    • Nehlin, J.O.1    Carlberg, M.2    Ronne, H.3
  • 33
    • 77956897434 scopus 로고
    • Phosphorylase kinase
    • edited by P. D. BOYER and E. G. KREBS. Academic Press, San Diego
    • PICKET-GIES, C. A., and D. A. WALSH, 1986 Phosphorylase kinase, pp. 395-459 in The Enzymes, edited by P. D. BOYER and E. G. KREBS. Academic Press, San Diego.
    • (1986) The Enzymes , pp. 395-459
    • Picket-Gies, C.A.1    Walsh, D.A.2
  • 34
    • 28444460297 scopus 로고    scopus 로고
    • Global analysis of protein phosphorylation in yeast
    • PTACEK, J., G. DEVGAN, G. MICHAUD, H. ZHU, X. ZHU et al., 2005 Global analysis of protein phosphorylation in yeast. Nature 438: 679-684.
    • (2005) Nature , vol.438 , pp. 679-684
    • Ptacek, J.1    Devgan, G.2    Michaud, G.3    Zhu, H.4    Zhu, X.5
  • 35
    • 0032530778 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae cAMP-dependent protein kinase controls entry into stationary phase through the Rim15p protein kinase
    • REINDERS, A., N. BURCKERT, T. BOLLER, A. WIEMKEN and C. DE VIRGILIO, 1998 Saccharomyces cerevisiae cAMP-dependent protein kinase controls entry into stationary phase through the Rim15p protein kinase. Genes Dev. 12: 2943-2955.
    • (1998) Genes Dev. , vol.12 , pp. 2943-2955
    • Reinders, A.1    Burckert, N.2    Boller, T.3    Wiemken, A.4    De Virgilio, C.5
  • 36
    • 0034705202 scopus 로고    scopus 로고
    • The yeast A kinases differentially regulate iron uptake and respiratory function
    • ROBERTSON, L. S., H. C. CAUSTON, R. A. YOUNG and G. R. FINK, 2000 The yeast A kinases differentially regulate iron uptake and respiratory function. Proc. Natl. Acad. Sci. USA 97: 5984-5988.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5984-5988
    • Robertson, L.S.1    Causton, H.C.2    Young, R.A.3    Fink, G.R.4
  • 37
    • 1642602693 scopus 로고    scopus 로고
    • The DNA damage checkpoint and PKA pathways converge on APC substrates and Cdc20 to regulate mitotic progression
    • SEARLE, J. S., K. L. SCHOLLAERT, B. J. WILKINS and Y. SANCHEZ, 2004 The DNA damage checkpoint and PKA pathways converge on APC substrates and Cdc20 to regulate mitotic progression. Nat. Cell Biol. 6: 138-145.
    • (2004) Nat. Cell Biol. , vol.6 , pp. 138-145
    • Searle, J.S.1    Schollaert, K.L.2    Wilkins, B.J.3    Sanchez, Y.4
  • 38
    • 0035413602 scopus 로고    scopus 로고
    • Physiological substrates of cAMP-dependent protein kinase
    • SHABB, J. B., 2001 Physiological substrates of cAMP-dependent protein kinase. Chem. Rev. 101: 2381-2411.
    • (2001) Chem. Rev. , vol.101 , pp. 2381-2411
    • Shabb, J.B.1
  • 39
    • 0030887842 scopus 로고    scopus 로고
    • Engineering unnatural nucleotide specificity for Rous sarcoma virus tyrosine kinase to uniquely label its direct substrates
    • SHAH, K., Y. LIU, C. DEIRMENGIAN and K. M. SHOKAT, 1997 Engineering unnatural nucleotide specificity for Rous sarcoma virus tyrosine kinase to uniquely label its direct substrates. Proc. Natl. Acad. Sci. USA 94: 3565-3570.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3565-3570
    • Shah, K.1    Liu, Y.2    Deirmengian, C.3    Shokat, K.M.4
  • 40
    • 0031658303 scopus 로고    scopus 로고
    • Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae
    • SINGER, M. S., A. KAHANA, A. J. WOLF, L. L. MEISINGER, S. E. PETERSON et al., 1998 Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150: 613-632.
    • (1998) Genetics , vol.150 , pp. 613-632
    • Singer, M.S.1    Kahana, A.2    Wolf, A.J.3    Meisinger, L.L.4    Peterson, S.E.5
  • 41
    • 0032925146 scopus 로고    scopus 로고
    • The catalytic subunit of cAMP-dependent protein kinase: Prototype for an extended network of communication
    • SMITH, C. M., E. RADZIO-ANDZELM, K. R. MADHUSUDAN, P. AKAMINE and S. S. TAYLOR, 1999 The catalytic subunit of cAMP-dependent protein kinase: prototype for an extended network of communication. Prog. Biophys. Mol. Biol. 71: 313-341.
    • (1999) Prog. Biophys. Mol. Biol. , vol.71 , pp. 313-341
    • Smith, C.M.1    Radzio-Andzelm, E.2    Madhusudan, K.R.3    Akamine, P.4    Taylor, S.S.5
  • 42
    • 0028540405 scopus 로고
    • Use of an oriented peptide library to determine the optimal substrates of protein kinases
    • SONGYANG, Z., S. BLECHNER, N. HOAGLAND, M. F. HOEKSTRA, H. PIWNICA-WORMS et al., 1994 Use of an oriented peptide library to determine the optimal substrates of protein kinases. Curr. Biol. 4: 973-982.
    • (1994) Curr. Biol. , vol.4 , pp. 973-982
    • Songyang, Z.1    Blechner, S.2    Hoagland, N.3    Hoekstra, M.F.4    Piwnica-Worms, H.5
  • 44
    • 0032835137 scopus 로고    scopus 로고
    • Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae
    • THEVELEIN, J. M., and J. H. DE WINDE, 1999 Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol. Microbiol. 33: 904-918.
    • (1999) Mol. Microbiol. , vol.33 , pp. 904-918
    • Thevelein, J.M.1    De Winde, J.H.2
  • 45
    • 0022633689 scopus 로고
    • Tandemly duplicated upstream control sequences mediate copper-induced transcription of the Saccharomyces cerevisiae copper-metallothionein gene
    • THIELE, D. J., and D. H. HAMER, 1986 Tandemly duplicated upstream control sequences mediate copper-induced transcription of the Saccharomyces cerevisiae copper-metallothionein gene. Mol. Cell Biol. 6: 1158-1163.
    • (1986) Mol. Cell Biol. , vol.6 , pp. 1158-1163
    • Thiele, D.J.1    Hamer, D.H.2
  • 46
    • 0023658335 scopus 로고
    • Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase
    • TODA, T., S. CAMERON, P. SASS, M. ZOLLER and M. WIGLER, 1987 Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50: 277-287.
    • (1987) Cell , vol.50 , pp. 277-287
    • Toda, T.1    Cameron, S.2    Sass, P.3    Zoller, M.4    Wigler, M.5
  • 47
    • 0037144578 scopus 로고    scopus 로고
    • Phosphorylation of Saccharomyces cerevisiae choline kinase on Ser30 and Ser85 by protein kinase A regulates phosphatidylcholine synthesis by the CDP-choline pathway
    • YU, Y., A. SREENIVAS, D. B. OSTRANDER and G. M. CARMAN, 2002 Phosphorylation of Saccharomyces cerevisiae choline kinase on Ser30 and Ser85 by protein kinase A regulates phosphatidylcholine synthesis by the CDP-choline pathway. J. Biol. Chem. 277: 34978-34986.
    • (2002) J. Biol. Chem. , vol.277 , pp. 34978-34986
    • Yu, Y.1    Sreenivas, A.2    Ostrander, D.B.3    Carman, G.M.4
  • 48
    • 0017078844 scopus 로고
    • The minimum substrate of cyclic AMP-stimulated protein kinase, as studied by synthetic peptides representing the phosphorylatable site of pyruvate kinase (type L) of rat liver
    • ZETTERQVIST, O., U. RAGNARSSON, E. HUMBLE, L. BERGLUND and L. ENGSTROM, 1976 The minimum substrate of cyclic AMP-stimulated protein kinase, as studied by synthetic peptides representing the phosphorylatable site of pyruvate kinase (type L) of rat liver. Biochem. Biophys. Res. Commun. 70: 696-703.
    • (1976) Biochem. Biophys. Res. Commun. , vol.70 , pp. 696-703
    • Zetterqvist, O.1    Ragnarsson, U.2    Humble, E.3    Berglund, L.4    Engstrom, L.5
  • 49
    • 0035860499 scopus 로고    scopus 로고
    • Global analysis of protein activities using proteome chips
    • ZHU, H., M. BILGIN, R. BANGHAM, D. HALL, A. CASAMAYOR et al., 2001 Global analysis of protein activities using proteome chips. Science 293: 2101-2105.
    • (2001) Science , vol.293 , pp. 2101-2105
    • Zhu, H.1    Bilgin, M.2    Bangham, R.3    Hall, D.4    Casamayor, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.