In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African green monkeys: Induction by chronic nicotine treatment

Drug Metabolism and Disposition

Volumn 34, Issue 9, 2006, Pages 1508-1515

  Lee, Anna M ^a   Yue, Jiang ^a   Tyndale, Rachel F ^a,b  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORZOXAZONE; CYTOCHROME P450 2E1; NICOTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CERCOPITHECUS; CIGARETTE SMOKING; CONTROLLED STUDY; DRUG CLEARANCE; DRUG HALF LIFE; DRUG METABOLISM; DRUG STRUCTURE; IN VITRO STUDY; IN VIVO STUDY; LIVER LEVEL; LONG TERM CARE; MALE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CERCOPITHECUS AETHIOPS; CHLORZOXAZONE; CYTOCHROME P-450 CYP2E1; ENZYME INDUCTION; LIVER; MALE; MICROSOMES, LIVER; MUSCLE RELAXANTS, CENTRAL; NICOTINE;

ANIMALIA; CERCOPITHECUS AETHIOPS; NICOTIANA TABACUM;

EID: 33747839122     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.106.010363     Document Type: Article

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