Bepridil Block of Recombinant Human Cardiac IKs Current Shows a Time-Dependent Unblock

Journal of Cardiovascular Pharmacology

Volumn 43, Issue 2, 2004, Pages 178-182

  Yumoto, Yoshihiro ^a   Horie, Minoru ^b,c   Kubota, Tomoyuki ^b   Ninomiya, Tomonori ^b   Kobori, Atsushi ^b   Takenaka, Kotoe ^b   Takano, Makoto ^b   Niwano, Shinichi ^a   Izumi, Tohru ^a  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Bepridil; Delayed rectifier K+ current; IKs; KCNE1; KCNQ1

Indexed keywords

BEPRIDIL; CALCIUM CHANNEL BLOCKING AGENT;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DELAYED RECTIFIER POTASSIUM CURRENT; DRUG EFFECT; DRUG MECHANISM; DRUG PROTEIN BINDING; GENE; GENETIC TRANSFECTION; HEART DEPOLARIZATION; HUMAN; HUMAN CELL; IC 50; KCNE1 GENE; KCNQ1 GENE; PATCH CLAMP; PHARMACOLOGICAL BLOCKING; POTASSIUM CURRENT; PRIORITY JOURNAL;

BEPRIDIL; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; HUMANS; KCNQ POTASSIUM CHANNELS; KCNQ1 POTASSIUM CHANNEL; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; TRANSFECTION;

EID: 1642500106     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200402000-00003     Document Type: Article

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