-
1
-
-
27544479318
-
Role of tyrosine kinase inhibitors in cancer therapy
-
Arora,A. and Scholar,E.M. (2005) Role of tyrosine kinase inhibitors in cancer therapy. J. Pharmacol. Exp. Ther., 315, 971-979.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.315
, pp. 971-979
-
-
Arora, A.1
Scholar, E.M.2
-
2
-
-
0026342401
-
Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
-
Knighton,D.R., Zheng,J.H., Ten Eyck,L.F., Ashford,V.A., Xuong,N.H., Taylor,S.S. and Sowadski,J.M. (1991) Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science, 253, 407-414.
-
(1991)
Science
, vol.253
, pp. 407-414
-
-
Knighton, D.R.1
Zheng, J.H.2
Ten Eyck, L.F.3
Ashford, V.A.4
Xuong, N.H.5
Taylor, S.S.6
Sowadski, J.M.7
-
3
-
-
0035812694
-
Protein structure prediction and structural genomics
-
Baker,D. and Sali,A. (2001) Protein structure prediction and structural genomics. Science, 294, 93-96.
-
(2001)
Science
, vol.294
, pp. 93-96
-
-
Baker, D.1
Sali, A.2
-
4
-
-
4444377864
-
CORES: An automated method for generating three-dimensional models of protein/ligand complexes
-
Hare,B.J., Walters,W.P., Caron,P.R. and Bemis,G.W. (2004) CORES: an automated method for generating three-dimensional models of protein/ ligand complexes. J. Med. Chem., 47, 4731-4740.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 4731-4740
-
-
Hare, B.J.1
Walters, W.P.2
Caron, P.R.3
Bemis, G.W.4
-
5
-
-
17144364076
-
From molecular modelling to drug design
-
In Rychlewski,K (ed.), Springer-Verlag
-
Cohen-Gonsaud,M., Catherinot,V., Labesse,G. and Douguet,D. (2004) From molecular modelling to drug design. In Rychlewski,K (ed.), Progress in Nucleic Acid Research and Molecular Biology. Springer-Verlag, Vol. 15, pp. 35-71.
-
(2004)
Progress in Nucleic Acid Research and Molecular Biology
, vol.15
, pp. 35-71
-
-
Cohen-Gonsaud, M.1
Catherinot, V.2
Labesse, G.3
Douguet, D.4
-
6
-
-
0036680148
-
Lead discovery using molecular docking
-
Shoichet,B.K., McGovern,S.L., Wei,B. and Irwin,J.J. (2002) Lead discovery using molecular docking. Curr. Opin. Chem. Biol., 6, 439-446.
-
(2002)
Curr. Opin. Chem. Biol.
, vol.6
, pp. 439-446
-
-
Shoichet, B.K.1
McGovern, S.L.2
Wei, B.3
Irwin, J.J.4
-
7
-
-
0242301182
-
Ligand-supported homology modelling of protein binding-sites using knowledge-based potentials
-
Evers,A., Gohlke,H. and Klebe,G. (2003) Ligand-supported homology modelling of protein binding-sites using knowledge-based potentials. J. Mol. Biol., 334, 327-345.
-
(2003)
J. Mol. Biol.
, vol.334
, pp. 327-345
-
-
Evers, A.1
Gohlke, H.2
Klebe, G.3
-
8
-
-
0142028937
-
Kinases, homology models, and high throughput docking
-
Diller,D.J. and Li,R.zz (2003) Kinases, homology models, and high throughput docking. J. Med. Chem., 46, 4638-4647.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4638-4647
-
-
Diller, D.J.1
Li, R.2
-
9
-
-
1642323740
-
Protein kinase inhibitors: Insights into drug design from structure
-
Noble,M.E., Endicott,J.A. and Johnson,L.N. (2004) Protein kinase inhibitors: insights into drug design from structure. Science, 303, 1800-1805.
-
(2004)
Science
, vol.303
, pp. 1800-1805
-
-
Noble, M.E.1
Endicott, J.A.2
Johnson, L.N.3
-
10
-
-
13444270892
-
The RCSB Protein Data Bank: A redesigned query system and relational database based on the mmCIF schema
-
Deshpande,N., Addess,K.J., Bluhm,W.F., Merino-Ott,J.C., Townsend-Merino,W., Zhang,Q., Knezevich,C., Xie,L., Chen,L., Feng,Z. et al. (2005) The RCSB Protein Data Bank: a redesigned query system and relational database based on the mmCIF schema. Nucleic Acids Res., 33, D233-D237.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Deshpande, N.1
Addess, K.J.2
Bluhm, W.F.3
Merino-Ott, J.C.4
Townsend-Merino, W.5
Zhang, Q.6
Knezevich, C.7
Xie, L.8
Chen, L.9
Feng, Z.10
-
11
-
-
0026345394
-
Protein kinase catalytic domain sequence database: Identification of conserved features of primary structure and classification of family members
-
Hanks,S.K. and Quinn,A.M. (1991) Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Meth. Enzymol., 200, 38-62.
-
(1991)
Meth. Enzymol.
, vol.200
, pp. 38-62
-
-
Hanks, S.K.1
Quinn, A.M.2
-
12
-
-
12344295462
-
ViTO: Tool for refinement of protein sequence-structure alignments
-
Catherinot,V. and Labesse,G. (2004) ViTO: tool for refinement of protein sequence-structure alignments. Bioinformatics, 20, 3694-3696.
-
(2004)
Bioinformatics
, vol.20
, pp. 3694-3696
-
-
Catherinot, V.1
Labesse, G.2
-
13
-
-
7544226311
-
PRODRG: A tool for high-throughput crystallography of protein-ligand complexes
-
Schuttelkopf,A.W. and van Aalten,D.M. (2004) PRODRG: a tool for high-throughput crystallography of protein-ligand complexes. Acta. Crystallogr. D. Biol. Crystallogr., 60, 1355-1363.
-
(2004)
Acta. Crystallogr. D. Biol. Crystallogr.
, vol.60
, pp. 1355-1363
-
-
Schuttelkopf, A.W.1
van Aalten, D.M.2
-
14
-
-
0001704085
-
SCORE: A new empirical method for estimating the binding affinity of a protein-ligand complex
-
Wang,R., Liu,L., Lai,L. and Tang,Y. (1998) SCORE: a new empirical method for estimating the binding affinity of a protein-ligand complex. J. Mol. Model, 4, 379-394.
-
(1998)
J. Mol. Model
, vol.4
, pp. 379-394
-
-
Wang, R.1
Liu, L.2
Lai, L.3
Tang, Y.4
-
15
-
-
20444369842
-
Rapid computational identification of the targets of protein kinase inhibitors
-
Rockey,W.M. and Elcock,A.H. (2005) Rapid computational identification of the targets of protein kinase inhibitors. J. Med. Chem., 48, 4138-4152.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 4138-4152
-
-
Rockey, W.M.1
Elcock, A.H.2
-
16
-
-
0038813693
-
The Src-selective kinase inhibitor PP1 also inhibits Kit and Bcr-Abl tyrosine kinases
-
Tatton,L., Morley,G.M., Chopra,R. and Khwaja,A. (2003) The Src-selective kinase inhibitor PP1 also inhibits Kit and Bcr-Abl tyrosine kinases. J. Biol. Chem., 278, 4847-4853.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 4847-4853
-
-
Tatton, L.1
Morley, G.M.2
Chopra, R.3
Khwaja, A.4
-
17
-
-
0035920248
-
Crystallographic approach to identification of cyclin-dependent kinase 4 (CDK4)-specific inhibitors by using CDK4 mimic CDK2 protein
-
Ikuta,M., Kamata,K., Fukasawa,K., Honma,T., Machida,T., Hirai,H., Suzuki-Takahashi,I., Hayama,T. and Nishimura,S. (2001) Crystallographic approach to identification of cyclin-dependent kinase 4 (CDK4)-specific inhibitors by using CDK4 mimic CDK2 protein. J. Biol. Chem., 276, 27548-27554.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27548-27554
-
-
Ikuta, M.1
Kamata, K.2
Fukasawa, K.3
Honma, T.4
Machida, T.5
Hirai, H.6
Suzuki-Takahashi, I.7
Hayama, T.8
Nishimura, S.9
-
18
-
-
0036720460
-
Progress toward virtual screening for drug side effects
-
Rockey,W.M. and Elcock,A.H. (2002) Progress toward virtual screening for drug side effects. Proteins, 48, 664-671.
-
(2002)
Proteins
, vol.48
, pp. 664-671
-
-
Rockey, W.M.1
Elcock, A.H.2
-
19
-
-
19944433530
-
Chemical proteomic analysis reveals alternative modes of action for pyrido[2,3-d]pyrimidine kinase inhibitors
-
Wissing,J., Godl,K., Brehmer,D., Blencke,S., Weber,M., Habenberger,P., Stein-Gerlach,M., Missio,A., Cotten,M., Muller,S. et al. (2004) Chemical proteomic analysis reveals alternative modes of action for pyrido[2,3-d]pyrimidine kinase inhibitors. Mol. Cell Proteomics, 3, 1181-1193.
-
(2004)
Mol. Cell Proteomics
, vol.3
, pp. 1181-1193
-
-
Wissing, J.1
Godl, K.2
Brehmer, D.3
Blencke, S.4
Weber, M.5
Habenberger, P.6
Stein-Gerlach, M.7
Missio, A.8
Cotten, M.9
Muller, S.10
-
20
-
-
1442351132
-
Protein flexibility in ligand docking and virtual screening to protein kinases
-
Cavasotto,C.N. and Abagyan,R.A. (2004) Protein flexibility in ligand docking and virtual screening to protein kinases. J. Mol. Biol., 337, 209-225.
-
(2004)
J. Mol. Biol.
, vol.337
, pp. 209-225
-
-
Cavasotto, C.N.1
Abagyan, R.A.2
|