The close relationship between heparanase and cyclooxygenase-2 expressions in signet-ring cell carcinoma of the stomach

Human Pathology

Volumn 37, Issue 9, 2006, Pages 1145-1152

  Ohtawa, Yasuyuki ^a   Naomoto, Yoshio ^a   Shirakawa, Yasuhiro ^a   Takaoka, Munenori ^a   Murata, Toshihiro ^a   Sonoda, Ryotaro ^a   Sakurama, Kazufumi ^a   Yamatsuji, Tomoki ^a   Gunduz, Mehmet ^a   Tsujigiwa, Hidetsugu ^a   Nagatsuka, Hitoshi ^a   Terada, Norihiko ^b   Itano, Satoshi ^b   Horiki, Sadayuki ^b   Yanagihara, Kazuyoshi ^c   Nakajima, Motowo ^d   Tanaka, Noriaki ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b Terada Hospital   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^d NOVARTIS PHARMA K K   (Japan)

Author keywords

Angiogenesis; COX 2; Gastric cancer; Heparanase; Metastasis; Signet ring cell carcinoma

Indexed keywords

CYCLOOXYGENASE 2; HEPARANASE; MESSENGER RNA;

ADULT; AGE; AGED; ANGIOGENESIS; ARTICLE; BLOOD VESSEL; CANCER INVASION; CELL LINE; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; ESOPHAGUS CANCER; FEMALE; GENE EXPRESSION; GROWTH; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MICROVASCULATURE; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX; SIGNET RING CARCINOMA; STOMACH CARCINOMA; UPREGULATION; VEIN;

ADULT; AGE FACTORS; AGED; CARCINOMA, SIGNET RING CELL; CELL LINE, TUMOR; CYCLOOXYGENASE 2; FEMALE; GLUCURONIDASE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEX FACTORS; STOMACH NEOPLASMS;

EID: 33747819586     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2006.04.005     Document Type: Article

References (27)

1. Jass J.R., Sobin L.H., and Watanabe H. The World Health Organization's histologic classification in gastrointestinal tumors. A commentary on the second edition. Cancer 66 (1990) 2162-2167
2. Kunisaki C., Shimada H., Nomura M., et al. Therapeutic strategy for signet ring cell carcinoma of the stomach. Br J Surg 91 (2004) 1319-1324
3. Yokota T., Kunii Y., Teshima S., et al. Signet ring cell carcinoma of the stomach: a clinicopathological comparison with the other histological types. Tohoku J Exp Med 186 (1998) 121-130
4. Kim D.Y., Park Y.K., Joo J.K., et al. Clinicopathological characteristics of signet ring cell carcinoma of the stomach. ANZ J Surg 74 (2004) 1060-1064
5. Nakajima M., Irimura T., and Nicolson G.L. Heparanases and tumor metastasis. J Cell Biochem 36 (1988) 157-167
6. Kjellen L., and Lindahl U. Proteoglycans: structures and interactions. Annu Rev Biochem 60 (1991) 443-475
7. David G. Integral membrane heparan sulfate proteoglyacan. FASEB J 7 (1993) 1023-1030
8. Vlodavsky I., Miao H.Q., Medalion B., et al. Involvement of heparan sulfate and related molecules in sequestration and growth promoting activity of fibroblast growth factor. Cancer Metastasis Rev 15 (1996) 177-186
9. Cohen T., Gitay-Goren H., Sharon R., et al. VEGF121, a vascular endothelial growth factor (VEGF) isoform lacking heparin binding ability, requires cell-surface heparan sulfates for efficient binding to the VEGF receptors of human melanoma cells. J Biol Chem 270 (1995) 11322-11326
10. Vlodavsky I., Bar-Shavit R., Ishai-Michaeli R., et al. Extracellular sequestration and release of fibroblast growth factor: a regulatory mechanism?. Trends Biochem Sci 16 (1991) 268-271
11. Koliopanos A., Friess H., Kleeff J., et al. Heparanase expression in primary and metastatic pancreatic cancer. Cancer Res 61 (2001) 4655-4659
12. Takaoka M., Naomoto Y., Ohkawa T., et al. Heparanase expression correlates with invasion and poor prognosis in gastric cancers. Lab Invest 83 (2003) 613-622
13. Okawa T., Naomoto Y., Nobuhisa T., et al. Heparanase is involved in angiogenesis in esophageal cancer through induction of cyclooxygenase-2. Clin Cancer Res 11 (2005) 7995-8005
14. Sekiguchi M., Sakakibara K., and Fujii G. Establishment of cultured cell lines derived from a human gastric carcinoma. Jpn J Exp Med 48 (1978) 61-68
15. Yabnagihara K., and Tsumuraya M. Transforming growth factor beta 1 induces apoptotic cell death in cultured human gastric carcinoma cells. Cancer Res 52 (1992) 4042-4045
16. Maxhimer J.B., Quiros R.M., Stewart R., et al. Heparanase-1 expression is associated with the metastatic potential of breast cancer. Surgery 132 (2002) 326-333
17. Gohji K., Hirano H., Okamoto M., et al. Expression of three extracellular matrix degradative enzymes in bladder cancer. Int J Cancer 95 (2001) 295-301
18. Friedmann Y., Vlodavsky I., Aingorn H., et al. Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis. Am J Pathol 157 (2000) 1167-1175
19. Zimmermann K.C., Sarbia M., Weber A.A., et al. Cyclooxygenase-2 expression in human esophageal carcinoma. Cancer Res 59 (1999) 198-204
20. Costa C., Soares R., Reis-Filho J.S., et al. Cyclo-oxygenase 2 expression is associated with angiogenesis and lymph node metastasis in human breast cancer. J Clin Pathol 55 (2002) 429-434
21. Soslow R.A., Dannenberg A.J., Rush D., et al. COX-2 is expressed in human pulmonary, colonic, and mammary tumors. Cancer 89 (2000) 2637-2645
22. Ristimaki A., Honkanen N., Jankala H., et al. COX-2 is expressed in human pulmonary, colonic, and mammary tumors. Cancer Res 57 (1997) 1276-1280
23. Wilson K.T., Fu S., Ramanujam K.S., et al. Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas. Cancer Res 58 (1998) 2929-2934
24. Hida T., Yatabe Y., Achiwa H., et al. Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. Cancer Res 58 (1998) 3761-3764
25. Shao L.M., Hunai J.T., Ya W.H., et al. Expression of COX-2 in stomach cancer and its relation of their biological features. Dig Surg 20 (2003) 107-114
26. Honjo S., Kasae S., Osaki M., et al. COX-2 correlation with F-box protein, Skp2 expression and prognosis in human gastric cancer. Int J Oncol 26 (2005) 353-360
27. Yasui W., Oue N., Augg P.P., et al. Molecular-pathological prognostic factors of gastric cancer: a review. Gastric Cancer 8 (2005) 86-94