Pathogenicity and response to topical antiviral therapy in a murine model of acyclovir-sensitive and acyclovir-resistant herpes simplex viruses isolated from the same patient

Journal of Clinical Virology

Volumn 37, Issue 1, 2006, Pages 34-37

  Lebel, Annie ^a   Boivin, Guy ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Acyclovir; Drug resistance; Herpes simplex virus; Mouse; Pathogenicity; Thymidine kinase

Indexed keywords

ACICLOVIR; ADENOSINE TRIPHOSPHATE; FOSCARNET; THYMIDINE KINASE;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BINDING SITE; CONTROLLED STUDY; EXPERIMENTAL MODEL; FEMALE; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; IMMUNE DEFICIENCY; INFECTION SENSITIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN MANIFESTATION; TOPICAL TREATMENT; TREATMENT OUTCOME; VIRUS ISOLATION; VIRUS MUTANT; VIRUS VIRULENCE; WILD TYPE;

ACYCLOVIR; ADMINISTRATION, TOPICAL; AMINO ACID SUBSTITUTION; ANIMALS; ANTIVIRAL AGENTS; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, VIRAL; FEMALE; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; MICE; MICE, HAIRLESS; MICE, INBRED HRS; MUTATION, MISSENSE; THYMIDINE KINASE; VIRULENCE;

EID: 33747809669     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2006.05.003     Document Type: Article

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