The hemophagocytic syndrome: Titrating continuous hemofiltration to the degree of lactic acidosis

Pediatric Hematology and Oncology

Volumn 23, Issue 7, 2006, Pages 599-610

  DiCarlo, Joseph ^a   Lui, Wendy Y S ^b   Frankel, Lorry ^a   Howell, William ^a   Schiffman, Joshua ^a   Alexander, Steven ^a  

^a STANFORD UNIVERSITY   (United States)

^b TUEN MUN HOSPITAL   (Hong Kong)

Author keywords

Hemofiltration; Hemophagocytic syndrome; Lactic acidosis; Multiple organ failure; Pediatrics

Indexed keywords

CYCLOSPORIN; CYTOKINE; DEXAMETHASONE; ETOPOSIDE; FERRITIN; FUROSEMIDE; LACTIC ACID; METHOTREXATE; METHYLPREDNISOLONE; TACROLIMUS; TRIACYLGLYCEROL;

ARTICLE; BRAIN DISEASE; CANDIDIASIS; CASE REPORT; DIALYSATE; EPSTEIN BARR VIRUS; FERRITIN BLOOD LEVEL; HEMOFILTRATION; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HEMOPHAGOCYTIC SYNDROME; HUMAN; LACTATE BLOOD LEVEL; LACTIC ACIDOSIS; LYMPHOPROLIFERATIVE DISEASE; MALE; MALIGNANT NEOPLASTIC DISEASE; MULTIPLE ORGAN FAILURE; SCHOOL CHILD; TRIACYLGLYCEROL BLOOD LEVEL; ULTRAFILTRATION;

ACIDOSIS, LACTIC; CHILD; CYTOKINES; HEMOFILTRATION; HUMANS; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MALE; METABOLIC CLEARANCE RATE; MULTIPLE ORGAN FAILURE;

EID: 33747774507     PISSN: 08880018     EISSN: 15210669     Source Type: Journal    
DOI: 10.1080/08880010600860768     Document Type: Article

References (27)

1. Lim ME, Kim KS. Hemophagocytic lymphohistiocytosis. Pediatr Infect Dis J. 1999;18:154-155.
2. Imashuku S, Hlbi S, Todo S. Hemophagocytic lymphohistiocytosis in infancy and childhood. J Pediatr. 1997;130:352-357.
3. Henter JI, Elinder G, Ost A. Diagnostic guidelines for hemophagocytic lymphohistiocytosis. The FHL Study Group of the Histiocyte Society. Semin Oncol. 1991;18:29-33.
4. Arico M, Janka G, Fischer A, et al. Hemophagocytic lymphohistiocytosis: report of 122 children from the International Registry. FHL Study Group of the Histiocyte Society. Leukemia. 1996;10:197-203.
5. Grom AA. Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities? Curr Opin Rheumatol. 2003;15:587-590.
6. Dhote R, Simon J, Papo T, et al. Reactive hemophagocytic syndrome in adult systemic disease: report of twenty-six cases and literature review. Arthritis Rheum. 2003;49:633-639.
7. Sullivan KE, Delaat CA, Douglas SD, Filipovich AH. Defective natural killer cell function in patients with hemophagocytic lymphohistiocytosis and in first degree relatives. Pediatr Res. 1998;44:465-468.
8. Egeler RM, Shapiro R, Loechelt B, Filipovich A. Characteristic immune abnormalities in hemophagocytic lymphohistiocytosis. J Pediatr Hematol Oncol. 1996;18:340-345.
9. Henter JI, Samuelsson-Horne A, Arico M, et al. Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood. 2002;100:2367-2373.
10. Levendoglu-Tugal O, Ozkaynak MF, LaGamma E, Sherbany A, Sandoval C, Jayabose S. Hemophagocytic lymphohistiocytosis presenting with thrombocytopenia in the newborn. J Pediatr Hematol Oncol. 2002;24:405-409.
11. Takahashi T, Abe T, Sato T, et al. Elevated sphingomyelinase and hypercytokinemia in hemophagocytic lymphohistiocytosis. J Pediatr Hematol Oncol. 2002;24:401-404.
12. Osugi Y, Hara J, Tagawa S, et al. Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosis. Blood. 1997;89:4100-4103.
13. Henter JI, Elinder G, Soder O, Hansson M, Andersson B, Andersson U. Hypercytokinemia in familial hemophagocytic lymphohistiocytosis. Blood. 1991;78:2918-2922.
14. DiCarlo JV, Alexander SR, Agarwal R, Schiffman JD. Continuous veno-venous hemofiltration may improve survival from acute respiratory distress syndrome after bone marrow transplantation or chemotherapy. J Pediatr Hematol Oncol. 2003;25:801-805.
15. DiCarlo JV, Dudley TE, Sherbotie JR, Kaplan BS, Costarino AT. Continuous arteriovenous hemofiltration/dialysis improves pulmonary gas exchange in children with multiple organ system failure. Crit Care Med. 1990;18:822-826.
16. Henter JI, Arico M, Egeler RM, et al. HLH-94: a treatment protocol for hemophagocytic lymphohistiocytosis. HLH study Group of the Histiocyte Society. Med Pediatr Oncol. 1997;28:342-347.
17. Harvey B, Hickman C, Hinson G, Ralph T, Mayer A. Severe lactic acidosis complicating metformin overdose successfully treated with high-volume venovenous hemofiltration and aggressive alkalinization. Pediatr Crit Care Med. 2005;6:598-601.
18. Ronco C, Tetta C, Mariano F, et al. Interpreting the mechanisms of continuous renal replacement therapy in sepsis: the peak concentration hypothesis. Artif Organs. 2003;27:792-801.
19. Di Carlo JV, Alexander SR. Hemofiltration for cytokine-driven illnesses: the mediator delivery hypothesis. Int J Artif Organs. 2005;28:777-786.
20. Administration USFaD. FDA Updated Public Health Notification: Gambro Prisma® Continuous Renal Replacement System. DOI.
21. Elhanan N, Skippen P, Nuthall G, Krahn G, Seear M. Citrate anticoagulation in pediatric continuous venovenous hemofiltration. Pediatr Nephrol. 2004;19:208-212.
22. Ronco C, Belomo R, Homel P, et al. Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial. Edtna Erca J. 2002;2(Suppl):7-12.
23. Bouman CS, Oudemans-Van Straaten HM, Tijssen JG, Zandstra DF, Kesecioglu J. Effects of early high-volume continuous venovenous hemofiltration on survival and recovery of renal function in intensive care patients with acute renal failure: a prospective, randomized trial. Crit Care Med. 2002;30:2205-2211.
24. Cole L, Bellomo R, Journois D, Davenport P, Baldwin I, Tipping P. High-volume haemofiltration in human septic shock. Intensive Care Med. 2001;27:978-986.
25. Honore PM, Jamez J, Wauthier M, et al. Prospective evaluation of short-term, high-volume isovolemic hemofiltration on the hemodynamic course and outcome in patients with intractable circulatory failure resulting from septic shock. Crit Care Med. 2000;28:3581-3587.
26. Keller F, Bohler J, Czock D, Zellner D, Mertz AK. Individualized drug dosage in patients treated with continuous hemofiltration. Kidney Int Suppl. 1999;72:S29-S31.
27. Munar MY, Doyle IC, Meyer MM. Cyclosporine and vancomycin disposition during continuous venovenous hemodiafiltration. Ann Pharmacother. 1995;29:374-377.