Pfs47, paralog of the male fertility factor Pfs48/45, is a female specific surface protein in Plasmodium falciparum

Molecular and Biochemical Parasitology

Volumn 149, Issue 2, 2006, Pages 216-222

  van Schaijk, Ben C L ^a   van Dijk, Melissa R ^b   van de Vegte Bolmer, Marga ^a   van Gemert, Geert Jan ^a   van Dooren, Maaike W ^b   Eksi, Saliha ^c   Roeffen, Will F G ^a   Janse, Chris J ^b   Waters, Andrew P ^b   Sauerwein, Robert W ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Gametocytes; Malaria; P47; Pfs47; Plasmodium falciparum; Sex specific protein; Transfection

Indexed keywords

PROTEIN; PROTEIN PFS45; PROTEIN PFS47; PROTEIN PFS48; UNCLASSIFIED DRUG;

ARTICLE; CELL INTERACTION; CONTROLLED STUDY; ERYTHROCYTE; FEMALE FERTILITY; GAMETOCYTE; MALE FERTILITY; MOLECULAR RECOGNITION; NONHUMAN; OOCYST; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SURFACE PROPERTY; WILD TYPE;

ANIMALS; ANTIGENS, PROTOZOAN; BASE SEQUENCE; DNA, PROTOZOAN; FEMALE; GENE TARGETING; GENES, PROTOZOAN; GERM CELLS; MALE; MEMBRANE GLYCOPROTEINS; OOCYSTS; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS;

PLASMODIUM FALCIPARUM;

EID: 33747749158     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2006.05.015     Document Type: Article

References (44)

1. Carter R., Coulson A., Bhatti S., Taylor B.J., and Elliott J.F. Predicted disulfide-bonded structures for three uniquely related proteins of Plasmodium falciparum, Pfs230, Pfs48/45 and Pf12. Mol Biochem Parasitol 71 May (1995) 203-210
2. Templeton T.J., and Kaslow D.C. Identification of additional members define a Plasmodium falciparum gene superfamily which includes Pfs48/45 and Pfs230. Mol Biochem Parasitol 101 June (1999) 223-227
3. Williamson K.C., Criscio M.D., and Kaslow D.C. Cloning and expression of the gene for Plasmodium falciparum transmission-blocking target antigen, Pfs230. Mol Biochem Parasitol 58 (1993) 355-358
4. Gerloff D.L., Creasey A., Maslau S., and Carter R. Structural models for the protein family characterized by gamete surface protein Pfs230 of Plasmodium falciparum. Proc Natl Acad Sci USA 102 September (38) (2005) 13598-13603
5. Thompson J., Janse C.J., and Waters A.P. Comparative genomics in Plasmodium: a tool for the identification of genes and functional analysis. Mol Biochem Parasitol 118 December (2) (2001) 147-154
6. van Dijk M.R., Janse C.J., Thompson J., et al. A central role for P48/45 in malaria parasite male gamete fertility. Cell 104 (2001) 153-164
7. Eksi S., and Williamson K.C. Male-specific expression of the paralog of malaria transmission-blocking target antigen Pfs230, PfB0400w. Mol Biochem Parasitol 122 (2002) 127-130
8. Sanders P.R., Gilson P.R., Cantin G.T., et al. Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum. J Biol Chem 280 December (48) (2005) 40169-40176
9. Ishino T., Chinzei Y., and Yuda M. Two proteins with 6-cys motifs are required for malarial parasites to commit to infection of the hepatocyte. Mol Microbiol 58 December (5) (2005) 1264-1275
10. Florens L., Washburn M.P., Raine J.D., et al. A proteomic view of the Plasmodium falciparum life cycle. Nature 419 October (6906) (2002) 520-526
11. Lasonder E., Ishihama Y., Andersen J.S., et al. Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry. Nature 419 October (2002) 537-542
12. Le Roch K.G., Zhou Y., Blair P.L., et al. Discovery of gene function by expression profiling of the malaria parasite life cycle. Science 301 September (5639) (2003) 1503-1508
13. Vermeulen A.N., Ponnudurai T., Beckers P.J., Verhave J.P., Smits M.A., and Meuwissen J.H. Sequential expression of antigens on sexual stages of Plasmodium falciparum accessible to transmission-blocking antibodies in the mosquito. J Exp Med 162 November (5) (1985) 1460-1476
14. Carter R., Graves P.M., Keister D.B., and Quakyi I.A. Properties of epitopes of Pfs 48/45, a target of transmission blocking monoclonal antibodies, on gametes of different isolates of Plasmodium falciparum. Parasite Immunol 12 November (6) (1990) 587-603
15. Targett G.A., Harte P.G., Eida S., Rogers N.C., and Ong C.S. Plasmodium falciparum sexual stage antigens: immunogenicity and cell-mediated responses. Immunol Lett 25 August (1-3) (1990) 77-81
16. Roeffen W., Mulder B., Teelen K., et al. Association between anti-Pfs48/45 reactivity and P. falciparum transmission-blocking activity in sera from Cameroon. Parasite Immunol 18 February (2) (1996) 103-109
17. Healer J., McGuinness D., Hopcroft P., Haley S., Carter R., and Riley E. Complement-mediated lysis of Plasmodium falciparum gametes by malaria-immune human sera is associated with antibodies to the gamete surface antigen Pfs230. Infect Immun 65 August (1997) 3017-3023
18. Williamson K.C., Keister D.B., Muratova O., and Kaslow D.C. Recombinant Pfs230, a Plasmodium falciparum gametocyte protein, induces antisera that reduce the infectivity of Plasmodium falciparum to mosquitoes. Mol Biochem Parasitol 75 (1995) 33-42
19. Roeffen W., Geeraedts F., Eling W., et al. Transmission blockade of Plasmodium falciparum malaria by anti-Pfs230-specific antibodies is isotype dependent. Infect Immun 63 February (2) (1995) 467-471
20. Carter R. Transmission blocking malaria vaccines. Vaccine 19 March (17-19) (2001) 2309-2314
21. Eksi S., Stump A., Fanning S.L., Shenouda M.I., Fujioka H., and Williamson K.C. Targeting and sequestration of truncated Pfs230 in an intraerythrocytic compartment during Plasmodium falciparum gametocytogenesis. Mol Microbiol 44 (2002) 1507-1516
22. Williamson K.C. Pfs230: from malaria transmission-blocking vaccine candidate toward function. Parasite Immunol 25 July (7) (2003) 351-359
23. Tomas A.M., Margos G., Dimopoulos G., et al. P25 and P28 proteins of the malaria ookinete surface have multiple and partially redundant functions. EMBO J 20 August (2001) 3975-3983
24. Ifediba T., and Vanderberg J.P. Complete in vitro maturation of Plasmodium falciparum gametocytes. Nature 294 November (1981) 364-366
25. Ponnudurai T., Lensen A.H., Leeuwenberg A.D., and Meuwissen J.H. Cultivation of fertile Plasmodium falciparum gametocytes in semi-automated systems. 1. Static cultures. Trans R Soc Trop Med Hyg 76 6 (1982) 812-818
26. Ponnudurai T., Lensen A.H., Van Gemert G.J., Bensink M.P., Bolmer M., and Meuwissen J.H. Infectivity of cultured Plasmodium falciparum gametocytes to mosquitoes. Parasitology 98 April (Pt 2) (1989) 165-173
27. Wu Y., Kirkman L.A., and Wellems T.E. Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine. Proc Natl Acad Sci USA 93 February (1996) 1130-1134
28. Fidock D.A., and Wellems T.E. Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil. Proc Natl Acad Sci USA 94 September (20) (1997) 10931-10936
29. Sambrook J., Russel W.D., and Molecular. Cloning: a laboratory manual. 3rd ed. (2001), Cold Spring Harbor Laboratory Press, Cold Spring Harbor
30. Su X.Z., Wu Y., Sifri C.D., and Wellems T.E. Reduced extension temperatures required for PCR amplification of extremely A + T-rich DNA. Nucleic Acids Res 24 April (1996) 1574-1575
31. Church G.M., and Gilbert W. Genomic sequencing. Proc Natl Acad Sci USA 81 April (7) (1984) 1991-1995
32. Roeffen W., Teelen K., van As J., vd Vegte-Bolmer M., Eling W., and Sauerwein R. Plasmodium falciparum: production and characterization of rat monoclonal antibodies specific for the sexual-stage Pfs48/45 antigen. Exp Parasitol 97 Januray (2001) 45-49
33. Bazin H. Rat hybridomas and rat monoclonal antibodies (1990), CRC Press, Boca Raton, Florida
34. Bousema T.J., Roeffen W., van der Kolk M., et al. Rapid onset of transmission-reducing antibodies in Javanese migrants exposed to malaria in Papua, Indonesia. Am J Trop Med Hyg 74 March (3) (2006)
35. Trang D.T., Huy N.T., Kariu T., Tajima K., and Kamei K. One-step concentration of malarial parasite-infected red blood cells and removal of contaminating white blood cells. Malar J 3 March (2004) 7
36. Ponnudurai T., van Gemert G.J., Bensink T., Lensen A.H., and Meuwissen J.H. Transmission blockade of Plasmodium falciparum: its variability with gametocyte numbers and concentration of antibody. Trans R Soc Trop Med Hyg 81 3 (1987) 491-493
37. Rawlings D.J., Fujioka H., Fried M., Keister D.B., Aikawa M., and Kaslow D.C. Alpha-tubulin II is a male-specific protein in Plasmodium falciparum. Mol Biochem Parasitol 56 December (1992) 239-250
38. Young J.A., Fivelman Q.L., Blair P.L., et al. The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification. Mol Biochem Parasitol 143 September (1) (2005) 67-79
39. Hall N., Karras M., Raine J.D., et al. A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses. Science 307 January (5706) (2005) 82-86
40. Khan S.M., Franke-Fayard B., Mair G.R., et al. Proteome analysis of separated male and female gametocytes reveals novel sex-specific Plasmodium biology. Cell 121 June (5) (2005) 675-687
41. Kaushal D.C., and Carter R. Characterization of antigens on mosquito midgut stages of Plasmodium gallinaceum. II. Comparison of surface antigens of male and female gametes and zygotes. Mol Biochem Parasitol 11 April (1984) 145-156
42. Bruggemann M., Teale C., Clark M., Bindon C., and Waldmann H. A matched set of rat/mouse chimeric antibodies. Identification and biological properties of rat H chain constant regions mu, gamma 1, gamma 2a, gamma 2b, gamma 2c, epsilon, and alpha. J Immunol 142 May (9) (1989) 3145-3150
43. Tsai Y.L., Hayward R.E., Langer R.C., Fidock D.A., and Vinetz J.M. Disruption of Plasmodium falciparum chitinase markedly impairs parasite invasion of mosquito midgut. Infect Immun 69 June (2001) 4048-4054
44. Triglia T., Duraisingh M.T., Good R.T., and Cowman A.F. Reticulocyte-binding protein homologue 1 is required for sialic acid-dependent invasion into human erythrocytes by Plasmodium falciparum. Mol Microbiol 55 January (1) (2005) 162-174