Depression of cardiac L-type calcium current by a scorpion venom fraction M1 following muscarinic receptors interaction involving adenylate cyclase pathway

Toxicon

Volumn 48, Issue 4, 2006, Pages 373-387

  Cheikh, Amani ^a,b   Benkhalifa, Rym ^a   Bescond, Jocelyn ^b   El Ayeb, Mohamed ^a   Raymond, Guy ^b   Cognard, Christian ^b   Potreau, Daniel ^b  

^a PASTEUR INSTITUTE OF TUNIS   (Tunisia)

^b UMR CNRS 6187   (France)

Author keywords

L type calcium current; Muscarinic acetylcholine receptor; Rat heart; Scorpion envenomation; Ventricular cardiomyocytes

Indexed keywords

ADENYLATE CYCLASE; ATROPINE; CALCIUM CHANNEL L TYPE; GUANINE NUCLEOTIDE BINDING PROTEIN; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; PERTUSSIS TOXIN; SCORPION VENOM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CALCIUM TRANSPORT; CONTROLLED STUDY; DEPOLARIZATION; ENZYME ACTIVITY; ENZYME INHIBITION; HEART CONTRACTION; HEART MUSCLE CELL; HEART VENTRICLE WALL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CYCLIC AMP; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RATS; RATS, WISTAR; RECEPTOR, MUSCARINIC M2; SCORPION VENOMS;

BUTHUS OCCITANUS TUNETANUS; SCORPIONES;

EID: 33747748513     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.06.016     Document Type: Article

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