Ghrelin receptor inverse agonists: Identification of an active peptide core and its interaction epitopes on the receptor

Molecular Pharmacology

Volumn 70, Issue 3, 2006, Pages 936-946

  Holst, Birgitte ^a   Lang, Manja ^b   Brandt, Erik ^a   Bach, Anders ^a   Howard, Andrew ^c   Frimurer, Thomas M ^d   Beck Sickinger, Annette ^b   Schwartz, Thue W ^a,d  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c MERCK RESEARCH LABORATORIES   (United States)

^d 7TM Pharma A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GHRELIN; SUBSTANCE P DERIVATIVE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG IDENTIFICATION; DRUG POTENCY; DRUG STRUCTURE; LIGAND BINDING; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; EPITOPES; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PEPTIDE HORMONES; PEPTIDES; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTANCE P;

EID: 33747603675     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.024422     Document Type: Article

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