The determination of high-affinity protein/inhibitor binding constants by electrospray ionization hydrogen/deuterium exchange mass spectrometry

Rapid Communications in Mass Spectrometry

Volumn 20, Issue 16, 2006, Pages 2478-2482

  Frego, Lee ^a   Gautschi, Elda ^a   Martin, Leslie ^a   Davidson, Walter ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DESORPTION; ENZYMES; MASS SPECTROMETRY;

BINDING CONSTANT; CONVENTIONAL APPROACH; D VALUES; EXCHANGE METHODS; HIGH AFFINITY; HYDROGEN/DEUTERIUM EXCHANGE; LIGAND BINDING; MATRIX-ASSISTED LASER DESORPTION IONIZATION MASS SPECTROMETRY; PROTEIN INHIBITORS; PROTEIN LIGANDS;

ELECTROSPRAY IONIZATION;

EID: 33747501385     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.2614     Document Type: Article

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