Nitric oxide production by pulmonary leukocytes from induced sputum in patients with asthma and its effect on epithelial cell viability

Archivum Immunologiae et Therapiae Experimentalis

Volumn 54, Issue 3, 2006, Pages 201-207

  Bieńkowska Haba, Małgorzata ^a   Liebhart, Jerzy ^b   Cembrzyńska Nowak, Monika ^a  

^a INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

^b WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

Alveolar epithelial cells; Asthma; Lung remodeling; Nitric oxide; Pulmonary leukocytes

Indexed keywords

CORTICOSTEROID; NITRIC OXIDE; PREDNISONE;

ADULT; AGED; ARTICLE; ASTHMA; CELL DAMAGE; CELL FREE SYSTEM; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; FEMALE; HUMAN; HUMAN CELL; INFLAMMATORY CELL; LEUKOCYTE; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM; MALE; SPUTUM; SUPERNATANT;

ADULT; AGED; ASTHMA; CELL COMMUNICATION; CELL LINE; CELL SURVIVAL; CULTURE MEDIA, CONDITIONED; FEMALE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; NITRIC OXIDE; PULMONARY ALVEOLI; RESPIRATORY MUCOSA; SPUTUM;

EID: 33747487476     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-006-0025-z     Document Type: Article

References (25)

1. Bogdan C. (2001): Nitric oxide and the immune response. Nat. Immunol., 2, 907-916.
2. Chakir J., Shannon J., Molet S., Fukakusa M., Elias J., Laviolette M., Boulet L. P. and Hamid Q. (2003): Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-β1, IL-11, IL-17, and type I and type III collagen expression. J. Allergy Clin. Immunol., 111, 1293-1298.
3. Coleman J. W. (2001): Nitric oxide in immunity and inflammation. Int. Immunopharmacol., 1, 1397-1406.
4. Eastmond N. C., Banks E. M. and Coleman J. W. (1997): Nitric oxide inhibits IgE-mediated degranulation of mast cells and is the principal intermediate in IFN-gamma-induced suppression of exocytosis. J. Immunol., 159, 1444-1450.
5. Fahy J. V., Kim K. W., Liu J. and Boushey H. A. (1995): Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. J. Allergy Clin. Immunol., 95, 843-852.
6. Gabazza E. C., Taguchi O., Tamaki S., Murashima S., Kobayashi H., Yasui H., Kobayashi T., Hataji O. and Adachi Y. (2000): Role of nitric oxide in airway remodelling. Clin. Sci., 98, 291-294.
7. Gavino R., Johnson L. and Bhandari V. (2002): Release of cytokines and apoptosis in fetal rat type II pneumocytes exposed to hyperoxia and nitric oxide: modulatory effects of dexamethasone and pentoxifylline. Cytokine, 20, 247-255.
8. Global Strategy for Asthma Management and Prevention NIH Pub. No 02-3659, January 1995 (updated 2002) www.ginasthma.com.
9. Hansel T. T., Kharitonov S. A., Donnelly L. E., Erin E. M., Currie M. G., Moore W. M., Manning P. T., Recker D. P. and Barnes P. J. (2003): A selective inhibitor of inducible nitric oxide synthase inhibits exhaled breath nitric oxide in healthy volunteers and asthmatics. FASEB J., 17, 1290-1300.
10. Harmanci E., Kebapci M., Metintas M. and Ozkan R. (2000): High-resolution computed tomography findings are correlated with disease severity in asthma. Respiration, 69, 420-426.
11. Ho Y. S., Liou H. B., Lin J. K., Jeng J. H., Pan M. H., Lin Y. P., Guo H. R., Ho S. Y., Lee C. C. and Wang Y. J. (2002): Lipid peroxidation and cell death mechanisms in pulmonary epithelial cells induced by peroxynitrite and nitric oxide. Arch. Toxicol., 76, 484-493.
12. Holgate S. T., Davies D. E., Puddicombe S., Richter A., Lackie P., Lordan J. and Howarth P. (2003): Mechanisms of airway epithelial damage: epithelial-mesenchymal interactions in the pathogenesis of asthma. Eur. Respir. J. Suppl., 44, S24-29.
13. Holgate S. T., Peters-Golden M., Panettieri R. A. and Henderson W. R. Jr. (2003): Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling. J. Allergy Clin. Immunol., 111 (suppl. 1), S18-34.
14. Holz O., Kips J. and Magnussen H. (2000): Update on sputum methodology. Eur. Respir. J., 16, 355-359.
15. Lappalainen U., Whitsett J. A., Wert S. E., Tichelaar J. W. and Bry K. (2005): Interleukin-1beta causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung. Am. J. Respir. Cell Mol. Biol., 32, 311-318.
16. Mahut B., Delclaux C., Tillie-Leblond I., Gosset P., Delacourt C., Zerah-Lancner F., Harf A. and de Blic J. (2004): Both inflammation and remodeling influence nitric oxide output in children with refractory asthma. J. Allergy Clin. Immunol., 113, 252-256.
17. Milner A. D. (1994): Nitric oxide. Eur. J. Pediatr., 153 (suppl. 2), s7-s11.
18. Moilanen E. and Vapaatalo H. (1995): Nitric oxide in inflammation and immune response. Ann. Med., 27, 359-367.
19. Narula P., Xu J., Kazzaz J. A., Robbins C. G., Davis J. M. and Horowitz S. (1998): Synergistic cytotoxicity from nitric oxide and hyperoxia in cultured lung cells. Am. J. Physiol., 274 (3 Pt 1), L411-416.
20. Olivieri D., Chetta A., del Donno M., Bertorelli G., Casalini A., Pesci A., Testi R. and Foresi A. (1997): Effect of short-term treatment with low-dose inhaled fluticasone propionate on airway inflammation and remodeling in mild asthma: a placebo-controlled study. Am. J. Respir. Crit. Care Med., 155, 1864-1871.
21. Pang G. T., Clancy R. L. and Reeves G. E. (1995): Isolation and functional characterization of T cells from human sputum. Clin. Exp. Immunol., 102, 642-648.
22. Payne D. N., Rogers A. V., Adelroth E., Bandi V., Guntupalli K. K., Bush A. and Jeffery P. K. (2003): Early thickening of the reticular basement membrane in children with difficult asthma. Am. J. Respir. Crit. Care Med., 167, 78-82.
23. Sont J. K., Willems L. N., Bel E. H., van Krieken J. H., Vandenbroucke J. P. and Sterk P. J. (1999): Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. The AMPUL Study Group. Am. J. Respir. Crit. Care Med., 159 (Pt 1), 1043-1051.
24. Stuehr D. J. and Marletta M. A. (1985): Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc. Natl. Acad. Sci. USA, 82, 7738-7742.
25. Xiong Y., Karupiah G., Hogan S. P., Foster P. S. and Ramsay A. J. (1999): Inhibition of allergic airway inflammation in mice lacking nitric oxide synthase 2. J. Immunol., 162, 445-452.