Functional brain imaging using a long intravenous half-life gadolinium-based contrast agent

American Journal of Neuroradiology

Volumn 27, Issue 7, 2006, Pages 1467-1471

  Morton, D W ^a   Keogh, B ^a   Lim, K ^a   Maravilla, Kenneth R ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORALOSE; CONTRAST MEDIUM; GADOFOSVESET; GADOLINIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN FUNCTION; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG HALF LIFE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; MALE; MEASUREMENT; NONHUMAN; OXYGEN CONSUMPTION; PLASMA HALF LIFE; RAT; SENSORY CORTEX; TECHNIQUE;

ANIMALS; CONTRAST MEDIA; ELECTRIC STIMULATION; FEASIBILITY STUDIES; FOOT; GADOLINIUM; HALF-LIFE; IMAGE ENHANCEMENT; IMAGING, THREE-DIMENSIONAL; INJECTIONS, INTRAVENOUS; MAGNETIC RESONANCE IMAGING; MALE; ORGANOMETALLIC COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; SOMATOSENSORY CORTEX;

EID: 33747476855     PISSN: 01956108     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Hyder F, Kida I, Behar KL, et al. Quantitative functional imaging of the brain: towards mapping neuronal activity by BOLD fMM. NMR Biomed 2001;14; 413-31
2. Arthurs OJ, Boniface S. How well do we understand the neural origins of the fMRI BOLD signal? Trends Neurosci 2002;25:27-31
3. Arthurs OJ, Williams EJ, Carpenter TA, et al. Linear coupling between functional magnetic resonance imaging and evoked potential amplitude in human somatosensory cortex. Neuroscience 2000;101:803-06
4. Glover GH, Lemieux SK, Drangova M, et al. Decomposition of inflow and blood oxygen level-dependent (BOLD) effects with dual-echo spiral gradient-recalled echo (GRE) fMM. Magn Reson Med 1996;35:299-308
5. Hoge RD, Atkinson J, Gill B, et al. Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: the deoxyhemoglobin dilution model. Magn Reson Med 1999;42:849-63
6. Mandeville JB, Marota JJ, Kosofsky BE, et al. Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn Reson Med 1998;39:615-24
7. Morii S, Ngai AC, Winn HR. Reactivity of rat pial arterioles and venules to adenosine and carbon dioxide: with detailed description of the closed cranial window technique in rats. J Cereb Blood Flow Metab 1986;6:34-41
8. Hyder F, Behar KL, Martin MA, et al. Dynamic magnetic resonance imaging of the rat brain during forepaw stimulation. J Cereb Blood Flow Metab 1994;14: 649-55
9. Morton DW, Maravilla KR, Meno JR, et al. Clinically relevant rat model for testing BOLD functional MR imaging techniques by using single-shot echoplanar imaging at 1.5 T. Radiology 2001;218:598-601
10. Macwhinney B, Cohen J, Provost J. The PsyScope experiment-building system. Spat Vis 1997;11:99-101
11. Parmelee DJ, Walovitch RC, Quellet HS, et al. Preclinical evaluation of the pharmacokinetics, biodistribution, and elimination of MS-325, a blood pool agent for magnetic resonance imaging. Invest Radiol 1997;32:741-47
12. Caravan P, Cloutier NJ, Greenfield MT, et al. The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates. J Am Chem Soc 2002;124:3152-62
13. Lauffer RB, Parmelee DJ, Dunham SU, et al. MS-325: albumin-targeted contrast agent for MR angiography. Radiology 1998;207:529-38
14. Lauffer RB, Parmalee DJ, Ouellet HS, et al. MS-325: a small-molecule vascular imaging agent for MR imaging. Acad Radiol 1996;3:S356-58
15. Bluemke DA, Stillman AE, Bis KG, et al. Carotid MR angiography: phase II study of safety and efficacy for MS-325. Radiology 2001;219:114-22