v-Src tyrosine phosphorylation of connexin43: Regulation of gap junction communication and effects on cell transformation

Cell Communication and Adhesion

Volumn 13, Issue 4, 2006, Pages 199-216

  Lin, Rue ^a   Martyn, Kendra D ^b   Guyette, Carrie V ^b   Lau, Alan F ^b,c   Warn Cramer, Bonnie J ^b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^c UNIVERSITY OF HAWAII   (United States)

Author keywords

Connexin43; Gap junction communication; MAP kinase; Phosphorylation; Transformation; v Src

Indexed keywords

ALANINE; CONNEXIN 43; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE P60; SERINE; TYROSINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL ASSAY; CELL COMMUNICATION; CELL MIGRATION; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; FIBROBLAST; GAP JUNCTION; GENE DISRUPTION; GENE MUTATION; INHIBITION KINETICS; ION EXCHANGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

AMINO ACID SUBSTITUTION; ANIMALS; CELL ADHESION; CELL COMMUNICATION; CELL MOVEMENT; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CONNEXIN 43; GAP JUNCTIONS; GENE EXPRESSION REGULATION; MODELS, BIOLOGICAL; MUTANT PROTEINS; ONCOGENE PROTEIN PP60(V-SRC); PHOSPHORYLATION; RATS;

EID: 33747459250     PISSN: 15419061     EISSN: 15435180     Source Type: Journal    
DOI: 10.1080/15419060600848516     Document Type: Article

References (41)

1. Beyer, E and Paul, D and Goodenough, D. (1987) Connexin43: A protein from rat heart homologous to a gap junction protein from liver. J Cell Biol, 105, pp. 2621-2629. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=2826492&Session=&searchQuery=J+Cell+ Biol%5BJournal+Name%5D+AND+105%5BVolume%5D+AND+2621%5BPage+ Number%5D+AND+19887%5BPublication+Date%5D+AND+Beyer%5BAuthor+ Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn= 1066-5277&vol=105&iss=&firstpage=2621
2. Cameron, S and Malik, S and Akaike, M and Lerner-Marmarosh, N and Yan, C and Lee, J and Abe, J and Yang, J. (2003) Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase1/ERK5 but not ERK1/2 kinase activation. J Biol Chem, 278, pp. 18682-18688. http://www4.infotrieve.com/newmedline/detail.asp?NameID=12637502& Session=&searchQuery=J+Biol+Chem%5BJournal+Name%5D+AND+ 278%5BVolume%5D+AND+18682%5BPage+Number%5D+AND+2003%5BPublication+ Date%5D+AND+Cameron%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0884-3996&vol=278& iss=&firstpage=18682 http://dx.doi.org/10.1074%2Fjbc.M213283200
3. Chandrasekhar, A and Merritt, M and Huh, S and Nicholson, B and Zucker, S. (2004) Connexin expression and cell coupling fail to reverse the v-src transformed growth characteristics of a Cx43-/- cell line. Cell Commun Adhes, 11, pp. 103-119. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=16194879&Session=&searchQuery= Cell+Commun+Adhes%5BJournal+Name%5D+AND+11%5BVolume%%5D+AND+ 103%5BPage+Number%5D+AND+2004%5BPublication+Date%5D+AND+ CChandrasekhar%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=1541-9061&vol= 11&iss=&firstpage=1103
4. Cheetham, G. (2004) Novel protein kinases and molecular mechanisms of autoinhibition. Curr Opin Struct Biol, 14, pp. 700-705. http://www4.infotrieve.com/newmedline/detail.asp?NameID=15582394& Session=&searchQuery=Curr+Opin+Struct+Biol%5BJournal+Name%5D+AND+ 14%5BVolume%5D+AND+700%5BPage+Number%5D+AND+2004%5BPublication+ Date%5D+AND+Cheetham%5BAuthor+Name%5Dcount=1 http://www.csa.com/htbin/linkabst.cgi?issn=0959-440Xvol=14&iss= &firstpage=700
5. Cottrell, G and Lin, R and Warn-Cramer, B and Lau, A and Burt, J. (2003) Mechanism of v-Src- and mitogen-activated protein kinase-induced reduction of gap junction communication. Am J Physiol Cell Physiol, 284, pp. C511-520. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=12388103&Session=&searchQuery=Am+J+Physiol+ Cell+Physiol%5BJournal+Name%5D+AND+284%5BVolume%5D+AND+C511%5BPage+ Number%5D+AND+2003%5BPublication+Date%5D+AND+Cottrell%5BAuthor+ Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=1040-0605&vol=284&iss=&firstpage=C511
6. Crow, D and Beyer, E and Paul, D and Kobe, S and Lau, A. (1990) Phosphorylation of connexin43 gap junction protein in uninfected and Rous sarcoma virus-transformed mammalian fibroblasts. Mol Cell Biol, 10, pp. 1754-1763. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=1690850&Session=&searchQuery=Mol+Cell+ Biol%5BJournal+Name%5D+AND+10%5BVolume%5D+AND+1754%5BPage+ Number%5D+AND+1990%5BPublication+Date%5D+AND+Crow%5BAuthor+ Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn= 1522-4724&vol=10&iss=&firstpage=1754
7. Crow, D and Kurata, W and Lau, A. (1992) Phosphorylation of connexin43 in cells containing mutant src oncogenes. Oncogene, 7, pp. 999-1003. http://www4.infotrieve.com/newmedline/detail.asp?NameID=1315016& Session=&searchQuery=Oncogene%5BJournal+Name%5D+AND+7%5BVolume% 5D+AND+999%5BPage+Number%5D+AND+1992%5BPublication+Date%5D+AND+ Crow%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=0950-9232&vol=7&iss=&firstpage=999
8. Duffy, H and Delmar, M and Spray, D. (2002) Formation of the gap junction nexus: Binding partners for connexins. J Physiol Paris, 96, pp. 243-249. http://www4.infotrieve.com/newmedline/detail.asp? NameID=12445902&Session=&searchQuery=J+Physiol+Paris%5BJournal+ Name%5D+AND+96%5BVolume%5D+AND+243%5BPage+Number%5D+AND+2002% 5BPublication+Date%5D+AND+Duffy%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0928-4257&vol= 96&iss=&firstpage=243
9. Filson, A and Azarnia, R and Beyer, E and Loewenstein, W and Brugge, J. (1990) Tyrosine phosphorylation of a gap junction protein correlates with inhibition of cell-to-cell communication. Cell Growth Differ, 1, pp. 661-668. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 1963075&Session=&searchQuery=Cell+Growth+Differ%5BJournal+ Name%5D+AND+1%5BVolume%5D+AND+661%5BPage+Number%5D+AND+ 1990%5BPublication+Date%5D+AND+Filson%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=1044-9523&vol= 1&iss=&firstpage=661
10. Frame, M. (2002) Src in cancer: Deregulation and consequences for cell behaviour. Biochim Biophys Acta, 1602, pp. 114-130. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 12020799&Session=&searchQuery=Biochim+Biophys+ Acta%5BJournal+Name%5D+AND+1602%5BVolume%5D+AND+114%5BPage+ Number%5D+AND+2002%5BPublication+Date%5D+AND+Frame%5BAuthor+ Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn= 1570-9639&vol=1602&iss=&firstpage=114
11. Frame, M. (2004) Newest findings on the oldest oncogene; how activated src does it. J Cell Sci, 117, pp. 989-998. http://www4.infotrieve.com/newmedline/detail.asp?NameID=14996930& Session=&searchQuery=J+Cell+Sci%5BJournal+Name%5D+AND+ 117%5BVolume%5D+AND+989%5BPage+Number%5D+AND+2004%5BPublication+ Date%5D+AND+Frame%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0269-3518&vol= 117&iss=&firstpage=989 http://dx.doi.org/10.1242%2Fjcs.01111
12. Frame, M and Fincham, V and Carragher, N and Wyke, J. (2002) v-Src's hold over actin and cell adhesions. Nat Rev Mol Cell Biol, 3, pp. 233-245. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 11994743&Session=&searchQuery=Nat+Rev+Mol+Cell+Biol%5BJournal+ Name%5D+AND+3%5BVolume%5D+AND+233%5BPage+Number%5D+AND+ 2002%5BPublication+Date%5D+AND+Frame%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=1471-0072&vol= 3&iss=&firstpage=233 http://dx.doi.org/10.1038%2Fnrm779
13. Giepmans, B. (2004) Gap junctions and connexin-interacting proteins. Cardiovasc Res, 62, pp. 233-245. http://www4.infotrieve.com/newmedline/detail.asp?NameID=15094344& Session=&searchQuery=Cardiovasc+Res%5BJournal+Name%5D+AND+ 62%5BVolume%5D+AND+233%5BPage+Number%5D+AND+2004%5BPublication+ Date%5D+AND+Giepmans%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0008-6363&vol= 62&iss=&firstpage=233 http://dx.doi.org/10.1016%2Fj.cardiores.2003.12.009
14. Giepmans, B and Verlaan, I and Hengeveld, T and Janssen, H and Calafat, J and Falk, M and Moolenaar, W. (2001) Gap junction protein connexin-43 interacts directly with microtubules. Curr Biol, 11, pp. 1364-1368. http://www4.infotrieve.com/newmedline/detail.asp?NameID=11553331& Session=&searchQuery=Curr+Biol%5BJournal+Name%5D+AND+ 11%5BVolume%5D+AND+1364%5BPage+Number%5D+AND+2001%5BPublication +Date%5D+AND+Giepmans%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0011-4014&vol= 11&iss=&firstpage=1364 http://dx.doi.org/ 10.1016%2FS0960-9822%2801%2900424-9
15. Goldberg, G and Lau, A. (1993) Dynamics of connexin43 phosphorylation in pp60v-src Transformed cells. Biochem J, 285, pp. 735-742. http://www.csa.com/htbin/ linkabst.cgi?issn=0264-6021&vol=285&iss=&firstpage=735
16. Herve, J and Bourmeyster, N and Sarrouilhe, D. (2004) Diversity in protein-protein interactions of connexins: Emerging roles. Biochim Biophys Acta, 1662, pp. 22-41. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=15033577&Session=&searchQuery=Biochim+ Biophys+Acta%5BJournal+Name%5D+AND+1662%5BVolume%5D+AND+22%5BPage+ Number%5D+AND+2004%5BPublication+Date%5D+AND+Herve%5BAuthor+ Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=1570-9639&vol=1662&iss=&firstpage=22 http://dx.doi.org/10.1016%2Fj.bbamem.2003.10.022
17. Hotz-Wagenblatt, A and Shalloway, D. (1993) Gap junctional communication and neoplastic transformation. Crit Rev Oncog, 4, pp. 541-558. http://www4.infotrieve.com/newmedline/detail.asp?NameID=8241323& Session=&searchQuery=Crit+Rev+Oncog%5BJournal+Name%5D+ AND+4%5BVolume%5D+AND+541%5BPage+Number%5D+AND+1993%5BPublication+ Date%5D+AND+Hotz%2DWagenblatt%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0893-9675&vol= 4&iss=&firstpage=541
18. Ito, S and Ito, Y and Senga, T and Hattori, S and Matsuo, S and Hamaguchi, M. (2005) v-Src requires Ras signaling for the suppression of gap junctional intercellular communication. Oncogene. Epub November http://www.csa.com/htbin/ linkabst.cgi?issn=0950-9232&vol=&iss=&firstpage
19. Kanemitsu, M and Loo, L and Simon, S and Lau, A and Eckhart, W. (1997) Tyrosine phosphorylation of connexin 43 by v-Src is mediated by SH2 and SH3 domain interactions. J Biol Chem, 272, pp. 22824-22831. http://www4.infotrieve.com/newmedline/detail.asp?NameID=9278444& Session=&searchQuery=J+Biol+Chem%5BJournal+Name%5D+AND+ 272%5BVolume%5D+AND+22824%5BPage+Number%5D+AND+1997%5BPublication+ Date%5D+AND+Kanemitsu%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0884-3996&vol= 272&iss=&firstpage=22824 http://dx.doi.org/ 10.1074%2Fjbc.272.36.22824
20. Lampe, P and Lau, A. (2004) The effects of connexin phosphorylation on gap junctional communication. Int J Biochem Cell Biol, 36, pp. 1171-1186. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 15109565&Session=&searchQuery=Int+J+Biochem+Cell+ Biol%5BJournal+Name%5D+AND+36%5BVolume%5D+AND+1171%5BPage+ Number%5D+AND+2004%5BPublication+Date%5D+AND+Lampe%5BAuthor+ Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn= 1357-2725&vol=36&iss=&firstpage=1171 http://dx.doi.org/10.1016%2FS1357-2725%2803%2900264-4
21. Lan, Z and Kurata, W and Martyn, K and Jin, C and Lau, A. (2005) Novel rab GAP-like protein, CIP85, interacts with connexin43 and induces its degradation. Biochem, 44, pp. 2385-2396. http://www.csa.com/htbin/ linkabst.cgi?issn=0006-2979&vol=44&liss=&firstpage=2385 http://dx.doi.org/10.1021%2Fbi048306w
22. Lee, S and Tomasetto, C and Paul, D and Keyomarsi, K and Sager, R. (1992) Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines. J Cell Biol, 118, pp. 1213-1221. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=1324944&Session=&searchQuery=J+Cell+ Biol%5BJournal+Name%5D+AND+118%5BVolume%5D+AND+1213%5BPage+ Number%5D+AND+1992%5BPublication+Date%5D+AND+Lee%5BAuthor+ Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=1066-5277&vol=118&iss=&firstpage=1213 http://dx.doi.org/10.1083%2Fjcb.118.5.1213
23. Lin, R and Warn-Cramer, B and Kurata, W and Lau, A. (2001a) v-Src-mediated phosphorylation of connexin43 on tyrosine disrupts gap junctional communication in mammalian cells. Cell Commun Adhes, 8, pp. 265-269. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 12064600&Session=&searchQuery=Cell+Commun+Adhes%5BJournal+ Name%5D+AND+8%5BVolume%5D+AND+265%5BPage+Number%5D+AND+ 2001%5BPublication+Date%5D+AND+Lin%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=1541-9061&vol= 8&iss=&firstpage=265
24. Lin, R and Warn-Cramer, B and Kurata, W and Lau, A. (2001b) v-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication. J Cell Biol, 154, pp. 815-827. http://www4.infotrieve.com/newmedline/detail.asp?NameID=11514593& Session=&searchQuery=J+Cell+Biol%5BJournal+Name%5D+AND+ 154%5BVolume%5D+AND+815%5BPage+Number%5D+AND+2001%5BPublication+ Date%5D+AND+Lin%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=1066-5277&vol=154& iss=&firstpage=815 http://dx.doi.org/10.1083%2Fjcb.200102027
25. Loewenstein, W and Kanno, Y. (1966) Intercellular communication and the control of tissue growth: Lack of communication between cancer cells. Nature, 209, pp. 1248-1249. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=5956321&Session=&searchQuery= Nature%5BJournal+Name%5D+AND+209%5BVolume%5D+AND+1248%5BPage+ Number%5D+AND+1966%5BPublication+Date%5D+AND+Loewenstein%5BAuthor+ Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn= 0028-0887&vol=209&iss=&firstpage=1248 http://dx.doi.org/ 10.1038%2F2091248a0
26. Loo, L and Berestecky, J and Kanemitsu, M and Lau, A. (1995) pp60src-mediated phosphorylation of connexin 43, a gap junction protein. J Biol Chem, 270, pp. 12751-12761. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=7539006&Session=&searchQuery=J+Biol+ Chem%5BJournal+Name%5D+AND+270%5BVolume%5D+AND+12751%5BPage+ Number%5D+AND+1995%5BPublication+Date%5D+AND+Loo%5BAuthor+ Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0884- 3996&vol=270&iss=&firstpage=12751 http://dx.doi.org/ 10.1074%2Fjbc.270.45.27099
27. Maldonado, P and Rose, B and Loewenstein, W. (1988) Growth factors modulate junctional cell-to-cell communication. J Membr Biol, 106, pp. 203-210. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 2854164&Session=&searchQuery=J+Membr+Biol%5BJournal+ Name%5D+AND+106%5BVolume%5D+AND+203%5BPage+Number%5D+AND+ 1988%5BPublication+Date%5D+AND+Maldonado%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0022-2631&vol=106& iss=&firstpage=203 http://dx.doi.org/10.1007%2FBF01872158
28. Martyn, K and Kurata, W and Warn-Cramer, B and Burt, J and TenBroek, E and Lau, A. (1997) Immortalized connexin43 knockout cell lines display a subset of biological properties associated with the transformed phenotype. Cell Growth Differ, 8, pp. 1015-1027. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 9300183&Session=&searchQuery=Cell+Growth+Differ%5BJournal+ Name%5D+AND+8%5BVolume%5D+AND+1015%5BPage+Number%5D+AND+ 1997%5BPublication+Date%5D+AND+Martyn%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=1044-9523&vol=8&iss= &firstpage=1015
29. Mesnil, M. (2002) Connexins and cancer. Biol Cell, 94, pp. 493-500. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=12566222&Session=&searchQuery=Biol+ Cell%5BJournal+Name%5D+AND+94%5BVolume%5D+AND+493%5BPage+Number%5D+AND+ 2002%5BPublication+Date%5D+AND+Mesnil%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=0248-4900&vol=94&iss= &firstpage=493 http://dx.doi.org/10.1016%2FS0248-4900%2802%2900025-4
30. Riley, D and Carragher, N and Frame, M and Wyke, J. (2001) The mechanism of cell cycle regulation by v-Src. Oncogene, 20, pp. 5941-5950. http://www4.infotrieve.com/newmedline/detail.asp?NameID= 11593401&Session=&searchQuery=Oncogene%5BJournal+Name%5D+AND+ 20%5BVolume%5D+AND+5941%5BPage+Number%5D+AND+2001%5BPublication+Date%5D+ AND+Riley%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=0950-9232&vol=20&iss=&firstpage=5941 http://dx.doi.org/10.1038%2Fsj.onc.1204826
31. Swenson, K and Piwinica-Worms, H and McNamee, H and Paul, D. (1990) Tyrosine phosphorylation of the gap junction protein connexin43 is required for the pp60v-src-induced inhibition of communication. Cell Regul, 1, pp. 989-1002. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=1966893&Session=&searchQuery=Cell+ Regul%5BJournal+Name%5D+AND+1%5BVolume%5D+AND+989%5BPage+Number%5D+AND+ 1990%5BPublication+Date%5D+AND+Swenson%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=1044-2030&vol=1&iss= &firstpage=989
32. Toyofuku, T and Akamatsu, Y and Zhang, H and Kuzuya, T and Tada, M and Hori, M. (2001) c-Src regulates the interaction between connexin-43 and ZO-1 in cardiac myocytes. J Biol Chem, 276, pp. 1780-1788. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=11035005&Session=&searchQuery=J+Biol+ Chem%5BJournal+Name%5D+AND+276%5BVolume%5D+AND+1780%5BPage+Number%5D+AND+ 2001%5BPublication+Date%5D+AND+Toyofuku%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=0884-3996&vol=276&iss=&firstpage=1780 http://dx.doi.org/10.1074%2Fjbc.M005826200
33. Warn-Cramer, B and Cottrell, G and Burt, J and Lau, A. (1998) Regulation of connexin-43 gap junctional intercellular communication by mitogen-activated protein kinase. J Biol Chem, 273, pp. 9188-9196. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=9535909&Session=&searchQuery=J+Biol+ Chem%5BJournal+Name%5D+AND+273%5BVolume%5D+AND+9188%5BPage+Number%5D+AND+ 1998%5BPublication+Date%5D+AND+Warn%2DCramer%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=0884-3996&vol=273&iss=&firstpage=9188 http://dx.doi.org/10.1074%2Fjbc.273.15.9188
34. Warn-Cramer, B and Lampe, P and Kurata, W and Kanemitsu, M and Loo, L and Eckhart, W and Lau, A. (1996) Characterization of the mitogen-activated protein kinase phosphorylation sites on the connexin-43 gap junction protein. J Biol Chem, 271, pp. 3779-3786. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=8631994&Session=&searchQuery=J+Biol+ Chem%5BJournal+Name%5D+AND+271%5BVolume%5D+AND+3779%5BPage+Number%5D+AND+ 1996%5BPublication+Date%5D+AND+Warn%2DCramer%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=0884-3996&vol=271&iss=&firstpage=3779 thttp://dx.doi.org/10.1074%2Fjbc.271.7.3779
35. Warn-Cramer, B and Lau, A. (2004) Regulation of gap junctions by tyrosine protein kinases. Biochim Biophys Acta, 1662, pp. 81-95. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=15033580&Session=&searchQuery=Biochim+Biophys+ Acta%5BJournal+Name%5D+AND+1662%5BVolume%5D+AND+81%5BPage+Number%5D+AND+ 2004%5BPublication+Date%5D+AND+Warn%2DCramer%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=1570-9639&vol=1662&iss=&firstpage=81 http://dx.doi.org/10.1016%2Fj.bbamem.2003.10.018
36. Warn-Cramer, B and Lin, R and Martyn, K and Guyette, C and Lau, A. (2003) Maintaining connexin43 gap junctional communication in v-Src cells does not alter growth properties associated with the transformed phenotype. Cell Commun Adhes, 10, pp. 299-303. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=14681032&Session=&searchQuery=Cell+Commun+ Adhes%5BJournal+Name%5D+AND+10%5BVolume%5D+AND+299%5BPage+Number%5D+AND+ 2003%5BPublication+Date%5D+AND+Warn%2DCramer%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/linkabst.cgi?issn=1541-9061&vol=10&iss= &firstpage=299
37. Yamasaki, H and Krutovskikh, V and Mesnil, M and Tanaka, T and Zaidan-Dagli, M and Omori, Y. (1999) Role of connexin (gap junction) genes in cell growth control and carcinogenesis. C R Acad Sci III, 322, pp. 151-159. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=10196667&Session=&searchQuery=C+R+Acad+Sci+ III%5BJournal+Name%5D+AND+322%5BVolume%5D+AND+151%5BPage+Number%5D+AND+ 1999%5BPublication+Date%5D+AND+Yamasaki%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=0249-6313&vol=322&iss=&firstpage=151
38. Yamasaki, H and Naus, C. (1996) Role of connexin genes in growth control. Carcinogenesis, 17, pp. 1199-1213. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=8681433&Session=&searchQuery= Carcinogenesis%5BJournal+Name%5D+AND+17%5BVolume%5D+AND+1199%5BPage+ Number%5D+AND+1996%5BPublication+Date%5D+AND+Yamasaki%5BAuthor+ Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=0143-3334&vol=17&iss=&firstpage=1199
39. Yeatman, T. (2004) A renaissance for SRC. Nat Rev Cancer, 4, pp. 470-480. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=15170449&Session=&searchQuery=Nat+Rev+ Cancer%5BJournal+Name%5D+AND+4%5BVolume%5D+AND+470%5BPage+Number%5D+ AND+2004%5BPublication+Date%5D+AND+Yeatman%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=1474-175X&vol=4&iss=&firstpage=470 http://dx.doi.org/10.1038%2Fnrc1366
40. Zhou, L and Kasperek, E and Nicholson, B. (1999) Dissection of the molecular basis of pp60(v-src) induced gating of connexin 43 gap junction channels. J Cell Biol, 144, pp. 1033-1045. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=10085299&Session=&searchQuery=J+Cell+ Biol%5BJournal+Name%5D+AND+144%5BVolume%5D+AND+1033%5BPage+Number%5D+ AND+1999%5BPublication+Date%5D+AND+Zhou%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=1066-5277&vol=144&iss=&firstpage=1033 http://dx.doi.org/10.1083%2Fjcb.144.5.1033
41. Zisch, A and Pazzagli, C and Freeman, A and Schneller, M and Hadman, M and Smith, J and Ruoslahti, E and Pasquale, E. (2000) Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses Oncogene, 19, pp. 177-187. http://www4.infotrieve.com/newmedline/ detail.asp?NameID=10644995&Session=&searchQuery=Oncogene% 5BJournal+Name%5D+AND+19%5BVolume%5D+AND+177%5BPage+Number%5D+AND+2000% 5BPublication+Date%5D+AND+Zisch%5BAuthor+Name%5D&count=1 http://www.csa.com/htbin/ linkabst.cgi?issn=0950-9232&vol=19&iss=&firstpage=177 http://dx.doi.org/10.1038%2Fsj.onc.1203304