Levobupivacaine versus racemic bupivacaine for spinal anaesthesia in orthopaedic major surgery;Levobupivacaina versus bupivacaina racemica per anestesia spinale in chirurgia ortopedica maggiore

Minerva Anestesiologica

Volumn 72, Issue 7-8, 2006, Pages 637-644

  Fattorini, F ^a,c   Ricci, Z ^a   Rocco, A ^a   Romano, R ^b   Pascarella, M A ^a   Pinto, G ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^c University of Rome La Sapienza II Faculty ^*  (Italy)

Author keywords

Anaesthesia, spinal; Anaesthetic technique; Anaesthetics, local; Levobupivacaine; Orthopedic surgical procedures; Racemic bupivacaine

Indexed keywords

ATROPINE; BUPIVACAINE; CHIROCAINA; EPHEDRINE; KETOROLAC; LEVOBUPIVACAINE; LOCAL ANESTHETIC AGENT;

ADULT; AGED; ANALGESIA; ARTICLE; BRADYCARDIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HEART RATE; HEMODYNAMICS; HUMAN; HYPOTENSION; LEG DISEASE; MAJOR CLINICAL STUDY; MAJOR SURGERY; MALE; MEAN ARTERIAL PRESSURE; NAUSEA; ORTHOPEDIC SURGERY; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRICK TEST; PROSPECTIVE STUDY; PUNCTURE; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SPINAL ANESTHESIA; STATISTICAL SIGNIFICANCE; SURGICAL TECHNIQUE; VISUAL ANALOG SCALE; WEAKNESS;

ADULT; AGED; AGED, 80 AND OVER; ANESTHESIA, SPINAL; ANESTHETICS, LOCAL; BLOOD PRESSURE; BUPIVACAINE; FEMALE; HEART RATE; HUMANS; MALE; MIDDLE AGED; ORTHOPEDIC PROCEDURES; PAIN, POSTOPERATIVE; PROSPECTIVE STUDIES; STEREOISOMERISM;

EID: 33747444646     PISSN: 03759393     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Burke D, Bannister J. Left-handed local anaesthetics. Curr Anaesth Crit Care 1999;10:262-9.
2. McLeod GA, Burke D. Levobupivacaine. Anaesthesia 2002;57:200.
3. Foster RH, Markham A. Levobupivacaine: a review of its pharmacology and use as a local anaesthetic. Drugs 2000;59:551-79.
4. Ivani G, Borghi B, Van Oven H. Levobupivacaine. Minerva Anestesiol 2001;67 Suppl 1:20-3.
5. Gristwood RW. Cardiac and CNS toxicity of levobupivacaine: strenghts of evidence for advantage over bupivacaine. Drug Saf 2002;25:153-63.
6. Huang YF, Pryor ME, Mather LE, Veering BT. Cardiovascular and central nervous system effects of intravenous levobupivacaine and bupivacaine in sheep. Anesth Anal 1998;86:797-804.
7. Bardsley H, Gristwood R, Baker H, Watson N, Nimno W. A comparison of the cardiovascular effects of levobupivacaine and rac-bupivacaine following intravenous administration to healthy volunteers. Br J Clin Pharmacol 1998;46:245-9.
8. Cox CR, Faccenda KA, Gilhooly C, Bannister J, Scott NB, Morrison LMM. Extradural S(-)-bupivacaine: comparison with racemic RS-bupivacaine. Br J Anaesth 1998;80:292-6.
9. Cox CR, Checketts MR, Mackenzie N, Scott NB, Bannister J. Comparison of S(-)-bupivacaine with racemic (RS)-bupivacaine in supraclavicular brachial plexus block. Br J Anaesth 1998;80:594-8.
10. Glaser C, Marhofer P, Zimpfer G, Heinz MT, Sitzwohl C, Kapral S et al. Levobupivacaine versus racemic bupivacaine for spinal anaesthesia. Anesth Anal 2002;94:194-8.
11. Burke D, Kennedy S, Bannister J. Spinal anaesthesia with 0.5 % S(-)-Bupivacaine for elective lower limb surgery. Reg An Pain Med 1999;24:519-23.
12. Panni M, Segal S. New local anesthetics: are they worth the cost? Anesthesiol Clin North Am 2003;21:19-38.
13. Lee YY, Muchhal K, Chan CK. Levobupivacaine versus racemic bupivacaine in spinal anaesthesia for urological surgery. Anaesth Intensive Care 2003;31:637-41.