Regulated release of nucleotides and UDP sugars from astrocytoma cells

Novartis Foundation Symposium

Volumn 276, Issue , 2006, Pages 73-84

  Lazarowski, Eduardo ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE GLUCOSE; CARRIER PROTEIN; NUCLEOTIDE; THROMBIN;

ANIMAL; ASTROCYTE; ASTROCYTOMA; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; ENDOPLASMIC RETICULUM; EXOCYTOSIS; GLIOMA; GOLGI COMPLEX; HUMAN; METABOLISM; PATHOLOGY; PHYSIOLOGY; REVIEW; SECRETION;

ADENOSINE DIPHOSPHATE GLUCOSE; ANIMALS; ASTROCYTES; ASTROCYTOMA; ENDOPLASMIC RETICULUM; EXOCYTOSIS; GLIOMA; GOLGI APPARATUS; HUMANS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR STRUCTURE; NUCLEOTIDES; THROMBIN; TUMOR CELLS, CULTURED;

EID: 33747431583     PISSN: 15282511     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (32)

1. Abbracchio MP, Boeynaems JM, Barnard EA et al 2003 Characterization of the UDP-glucose receptor (re-named here the P2Y(14) receptor) adds diversity to the P2Y receptor family. Trends Pharmacol Sci 24:52-55
2. Bankston LA, Guidotti G 1996 Characterization of ATP transport into chromaffin granule ghosts - Synergy of ATP and serotonin accumulation in chromaffin granule ghosts. J Biol Chem 271:17132-17138
3. Bianco F, Fumagalli M, Pravettoni E et al 2005a Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia. Brain Res Brain Res Rev 48:144-156
4. Bianco F, Pravettoni E, Colombo A et al 2005b Astrocyte-derived ATP Induces vesicle shedding and IL-1beta release from microglia. J Immunol 174:7268-7277
5. Citron BA, Smirnova IV, Arnold PM, Festoff BW 2000 Upregulation of neurotoxic serine proteases, prothrombin, and protease-activated receptor 1 early after spinal cord injury. J Neurotrauma 17:1191-1203
6. Coco S, Calegari F, Pravettoni E et al 2003 Storage and release of ATP from astrocytes in culture. J Biol Chem 278:1354-1362
7. Dean GE, Fishkes H, Nelson PJ, Rudnick G 1984 The hydrogen ion-pumping adenosine triphosphatase of platelet dense granule membrane. Differences from F1F0- and phosphoenzyme-type ATPases. J Biol Chem 259:9569-9574
8. Evans RJ, Derkach V, Surprenant A 1992 ATP mediates fast synaptic transmission in mammalian neurons. Nature 357:503-505
9. Festoff BW, D'Andrea MR, Citron BA, Salcedo RM, Smirnova IV, Andrade-Gordon P 2000 Motor neuron cell death in wobbler mutant mice follows overexpression of the G-protein-coupled, protease-activated receptor for thrombin. Mol Med 6:410-429
10. Fumagalli M, Brambilla R, D'Ambrosi N et al 2003 Nucleotide-mediated calcium signaling in rat cortical astrocytes: Role of P2X and P2Y receptors. Glia 43:218-230
11. Grabham P, Cunningham DD 1995 Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: involvement of tyrosine phosphorylation. J Neurochem 64:583-591
12. Gualix J, Pintor J, Miras-Portugal MT 1999 Characterization of nucleotide transport into rat brain synaptic vesicles. J Neurochem 73:1098-1104
13. Hirschberg CB, Robbins PW, Abeijon C 1998 Transporters of nucleotide sugars, ATP, and nucleotide sulfate in the endoplasmic reticulum and Golgi apparatus. Annu Rev Biochem 67:49-69
14. Hughes AR, Harden TK 1986 Adenosine and muscarinic cholinergic receptors attenuate cyclic AMP accumulation by different mechanisms in 1321N1 astrocytoma cells. J Pharmacol Exp Ther 237:173-178
15. Ji KA, Yang MS, Jou I, Shong MH, Joe EH 2004 Thrombin induces expression of cytokine-induced SH2 protein (CIS) in rat brain astrocytes: Involvement of phospholipase A(2), cyclooxygenase, and lipoxygenase. Glia 48:102
16. Jimenez AI, Castro E, Communi D, Boeynaems JM, Delicado EG, Miras-Portugal MT 2000 Coexpression of several types of metabotropic nucleotide receptors in single cerebellar astrocytes. J Neurochem 75:2071-2079
17. Joseph SM, Buchakjian MR, Dubyak GR 2003 Colocalization of ATP release sites and ecto-ATPase activity at the extracellular surface of human astrocytes. J Biol Chem 278:23342-23342
18. Lazarowski ER, Harden TK 1999 Quantitation of extracellular UTP using a sensitive enzymatic assay. Br J Pharmacol 127:1272-1278
19. Lazarowski ER, Watt WC, Stutts MJ, Boucher RC, Harden TK 1995 Pharmacological selectivity of the cloned human P2U purinoceptor - potent activation by diadenosine tetraphosphate. Br J Pharmacol 116:1619-1627
20. Lazarowski ER, Homolya L, Boucher RC, Harden TK 1997a Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation. J Biol Chem 272:24348-24354
21. Lazarowski ER, Homolya L, Boucher RC, Harden TK 1997b Identification of an ectonucleoside diphosphokinase and its contribution to interconversion of P2 receptor agonists. J Biol Chem 272:20402-20407
22. Lazarowski ER, Boucher RC, Harden TK 2000 Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphatase and nucleoside diphosphokinase to extracellular nucleotide concentrations. J Biol Chem 275:31061-31068
23. Lazarowski ER, Boucher RC, Harden TK 2003a Mechanisms of release of nucleotides and integration of their action as P2X- and P2Y-receptor activating molecules. Mol Pharmacol 64:785-795
24. Lazarowski ER, Shea DA, Boucher RC, Harden TK 2003b Release of cellular UDP-glucose as a potential extracellular signaling molecule. Mol Pharmacol 63:1190-1197
25. Lazarowski ER, Tarran R, Grubb BR, van Heusden CA, Okada S, Boucher RC 2004 Nucleotide release provides a mechanism for airway surface liquid homeostasis. J Biol Chem 279:36855-36864
26. Leloir LF 1971 Two decades of research on the biosynthesis of saccharides. Science 172:1299-1303
27. Moore DJ, Murdock PR, Watson JM et al 2003 GPR105, a novel Gi/o-coupled UDP-glucose receptor expressed on brain glia and peripheral immune cells, is regulated by immunologic challenge: possible role in neuroimmune function. Brain Res Mol Brain Res 118:10-23
28. Norambuena L, Marchant L, Berninsone P, Hirschberg CB, Silva H, Orellana A 2002 Transport of UDP-galactose in plants. Identification and functional characterization of AtUTr1, an Arabidopsis thaliana UDP-galactos/UDP-glucose transporter. J Biol Chem 277:32923-32929
29. Parodi AJ 2000 Protein glucosylation and its role in protein folding. Annu Rev Biochem 69:69-93
30. Ryu J, Pyo H, Jou I, Joe E 2000 Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B. J Biol Chem 275:29955-29959
31. Striggow F, Riek M, Breder J, Henrich-Noack P, Reymann KG, Reiser G 2000 The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations. Proc Natl Acad Sci USA 97:2264-2269
32. Suda T, Kamiyama S, Suzuki M et al 2004 Molecular cloning and characterization of a human multisubstrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection. J Biol Chem 279:26469-26474