-
1
-
-
0032841181
-
Growth factor independence and BCR-ABL transformation: promise and pitfalls of murine model systems and assays
-
Ghaffari S., et al. Growth factor independence and BCR-ABL transformation: promise and pitfalls of murine model systems and assays. Leukemia 13 (1999) 1200-1206
-
(1999)
Leukemia
, vol.13
, pp. 1200-1206
-
-
Ghaffari, S.1
-
2
-
-
0000286732
-
A minute chromosome in human chronic granulocytic leukemia
-
Nowell P.C., and Hungerford D.A. A minute chromosome in human chronic granulocytic leukemia. Science 132 (1960) 1497
-
(1960)
Science
, vol.132
, pp. 1497
-
-
Nowell, P.C.1
Hungerford, D.A.2
-
3
-
-
0015694748
-
A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
-
Rowly J.D. A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature 243 (1973) 290-293
-
(1973)
Nature
, vol.243
, pp. 290-293
-
-
Rowly, J.D.1
-
4
-
-
0021802841
-
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
-
Shtivelman E., et al. Fused transcript of abl and bcr genes in chronic myelogenous leukaemia. Nature 315 (1985) 550-554
-
(1985)
Nature
, vol.315
, pp. 550-554
-
-
Shtivelman, E.1
-
5
-
-
0023636773
-
Novel chimaeric protein expressed in Philadelphia positive acute lymphoblastic leukaemia
-
Walker L.C., et al. Novel chimaeric protein expressed in Philadelphia positive acute lymphoblastic leukaemia. Nature 329 (1987) 851-853
-
(1987)
Nature
, vol.329
, pp. 851-853
-
-
Walker, L.C.1
-
6
-
-
2542441665
-
The BCR-ABL story: bench to bedside and back
-
Wong S., and Witte O.N. The BCR-ABL story: bench to bedside and back. Annu. Rev. Immunol. 22 (2004) 247-306
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 247-306
-
-
Wong, S.1
Witte, O.N.2
-
7
-
-
0017653321
-
Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage
-
Fialkow P.J., et al. Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage. Am. J. Med. 63 (1977) 125-130
-
(1977)
Am. J. Med.
, vol.63
, pp. 125-130
-
-
Fialkow, P.J.1
-
8
-
-
0014143533
-
Clonal origin of chronic myelocytic leukemia in man
-
Fialkow P.J., et al. Clonal origin of chronic myelocytic leukemia in man. Proc. Natl. Acad. Sci. U S A 58 (1967) 1468-1471
-
(1967)
Proc. Natl. Acad. Sci. U S A
, vol.58
, pp. 1468-1471
-
-
Fialkow, P.J.1
-
9
-
-
14644425319
-
Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia
-
Ren R. Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia. Nat. Rev. Cancer 5 (2005) 172-183
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 172-183
-
-
Ren, R.1
-
10
-
-
33745888156
-
Combined effects of novel tyrosine kinase inhibitor AMN107 and histone deacetylase inhibitor LBH589 against BCR-ABL expressing human leukemia cells
-
Fiskus W., et al. Combined effects of novel tyrosine kinase inhibitor AMN107 and histone deacetylase inhibitor LBH589 against BCR-ABL expressing human leukemia cells. Blood 108 2 (2006) 645-652
-
(2006)
Blood
, vol.108
, Issue.2
, pp. 645-652
-
-
Fiskus, W.1
-
11
-
-
0030853063
-
The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL-positive cells
-
Deininger M.W., et al. The tyrosine kinase inhibitor CGP57148B selectively inhibits the growth of BCR-ABL-positive cells. Blood 90 (1997) 3691-3698
-
(1997)
Blood
, vol.90
, pp. 3691-3698
-
-
Deininger, M.W.1
-
12
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of BCR-ABL positive cells
-
Druker B.J., et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of BCR-ABL positive cells. Nat. Med. 2 (1996) 561-566
-
(1996)
Nat. Med.
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
-
13
-
-
0016640079
-
Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome
-
Lozzio C.B., and Lozzio B.B. Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood 45 (1975) 321-334
-
(1975)
Blood
, vol.45
, pp. 321-334
-
-
Lozzio, C.B.1
Lozzio, B.B.2
-
14
-
-
0026648901
-
Selective interactions of transforming and normal abl proteins with ATP, tyrosine-copolymer substrates, and tyrphostins
-
Anafi M., et al. Selective interactions of transforming and normal abl proteins with ATP, tyrosine-copolymer substrates, and tyrphostins. J. Biol. Chem. 267 (1992) 4518-4523
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 4518-4523
-
-
Anafi, M.1
-
15
-
-
0027332537
-
Tyrphostin-induced inhibition of p210BCR-ABL tyrosine kinase activity induces K562 to differentiate
-
Anafi M., et al. Tyrphostin-induced inhibition of p210BCR-ABL tyrosine kinase activity induces K562 to differentiate. Blood 82 (1993) 3524-3529
-
(1993)
Blood
, vol.82
, pp. 3524-3529
-
-
Anafi, M.1
-
16
-
-
0030031766
-
Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative
-
Buchdunger E., et al. Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. Cancer Res. 56 (1996) 100-104
-
(1996)
Cancer Res.
, vol.56
, pp. 100-104
-
-
Buchdunger, E.1
-
17
-
-
15944404601
-
The development of imatinib as a therapeutic agent for chronic myeloid leukemia
-
Deininger M., et al. The development of imatinib as a therapeutic agent for chronic myeloid leukemia. Blood 105 (2005) 2640-2653
-
(2005)
Blood
, vol.105
, pp. 2640-2653
-
-
Deininger, M.1
-
18
-
-
0034032012
-
BCR-ABL tyrosine kinase activity regulates the expression of multiple genes implicated in the pathogenesis of chronic myeloid leukemia
-
Deininger M.W., et al. BCR-ABL tyrosine kinase activity regulates the expression of multiple genes implicated in the pathogenesis of chronic myeloid leukemia. Cancer Res. 60 (2000) 2049-2055
-
(2000)
Cancer Res.
, vol.60
, pp. 2049-2055
-
-
Deininger, M.W.1
-
19
-
-
0032913704
-
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia
-
Drexler H.G., et al. Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia. Leuk. Res. 23 (1999) 207-215
-
(1999)
Leuk. Res.
, vol.23
, pp. 207-215
-
-
Drexler, H.G.1
-
20
-
-
0018688025
-
"Pre-B" phenotypes in blast crisis of Ph1 positive CML: evidence for a pluripotential stem cell "target"
-
Greaves M.F., et al. "Pre-B" phenotypes in blast crisis of Ph1 positive CML: evidence for a pluripotential stem cell "target". Leuk. Res. 3 (1979) 181-191
-
(1979)
Leuk. Res.
, vol.3
, pp. 181-191
-
-
Greaves, M.F.1
-
21
-
-
0017412602
-
A non-T, non-B human leukemia cell line (NALM-1): establishment of the cell line and presence of leukemia-associated antigens
-
Minowada J., et al. A non-T, non-B human leukemia cell line (NALM-1): establishment of the cell line and presence of leukemia-associated antigens. J. Natl. Cancer Inst. 59 (1977) 83-87
-
(1977)
J. Natl. Cancer Inst.
, vol.59
, pp. 83-87
-
-
Minowada, J.1
-
22
-
-
0034670036
-
The molecular biology of chronic myeloid leukemia
-
Deininger M.W., et al. The molecular biology of chronic myeloid leukemia. Blood 96 (2000) 3343-3356
-
(2000)
Blood
, vol.96
, pp. 3343-3356
-
-
Deininger, M.W.1
-
23
-
-
0037049763
-
Studying the pathogenesis of BCR-ABL+ leukemia in mice
-
Van Etten R.A. Studying the pathogenesis of BCR-ABL+ leukemia in mice. Oncogene 21 (2002) 8643-8651
-
(2002)
Oncogene
, vol.21
, pp. 8643-8651
-
-
Van Etten, R.A.1
-
24
-
-
0023410428
-
In vitro transformation of immature hematopoietic cells by the P210 BCR-ABL oncogene product of the Philadelphia chromosome
-
McLaughlin J., et al. In vitro transformation of immature hematopoietic cells by the P210 BCR-ABL oncogene product of the Philadelphia chromosome. Proc. Natl. Acad. Sci. U S A 84 (1987) 6558-6562
-
(1987)
Proc. Natl. Acad. Sci. U S A
, vol.84
, pp. 6558-6562
-
-
McLaughlin, J.1
-
25
-
-
0013769967
-
An assay for cellular transformation by SV40
-
Tordaro G.J., and Green H. An assay for cellular transformation by SV40. Virology 23 (1964) 117-119
-
(1964)
Virology
, vol.23
, pp. 117-119
-
-
Tordaro, G.J.1
Green, H.2
-
26
-
-
0023263055
-
The CML-specific P210 bcr/abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts
-
Daley G.Q., et al. The CML-specific P210 bcr/abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts. Science 237 (1987) 532-535
-
(1987)
Science
, vol.237
, pp. 532-535
-
-
Daley, G.Q.1
-
27
-
-
0024603114
-
The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc
-
Lugo T.G., and Witte O.N. The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc. Mol. Cell. Biol. 9 (1989) 1263-1270
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 1263-1270
-
-
Lugo, T.G.1
Witte, O.N.2
-
28
-
-
0026739538
-
Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context
-
Renshaw M.W., et al. Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context. Embo. J. 11 (1992) 3941-3951
-
(1992)
Embo. J.
, vol.11
, pp. 3941-3951
-
-
Renshaw, M.W.1
-
29
-
-
0025348013
-
Tyrosine kinase activity and transformation potency of BCR-ABL oncogene products
-
Lugo T.G., et al. Tyrosine kinase activity and transformation potency of BCR-ABL oncogene products. Science 247 (1990) 1079-1082
-
(1990)
Science
, vol.247
, pp. 1079-1082
-
-
Lugo, T.G.1
-
30
-
-
0033959024
-
Abl kinase but not PI3-kinase links to the cytoskeletal defects in BCR-ABL transformed cells
-
Gaston I., et al. Abl kinase but not PI3-kinase links to the cytoskeletal defects in BCR-ABL transformed cells. Exp. Hematol. 28 (2000) 351
-
(2000)
Exp. Hematol.
, vol.28
, pp. 351
-
-
Gaston, I.1
-
31
-
-
0034649515
-
BCR-ABL has a greater intrinsic capacity than v-Abl to induce the neoplastic expansion of myeloid cells in vivo
-
Gross A.W., and Ren R. BCR-ABL has a greater intrinsic capacity than v-Abl to induce the neoplastic expansion of myeloid cells in vivo. Oncogene 19 (2000) 6286-6296
-
(2000)
Oncogene
, vol.19
, pp. 6286-6296
-
-
Gross, A.W.1
Ren, R.2
-
32
-
-
0029790791
-
The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene
-
Senechal K., et al. The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene. J. Biol. Chem. 271 (1996) 23255-23261
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 23255-23261
-
-
Senechal, K.1
-
33
-
-
0031038399
-
Direct binding of CRKL to BCR-ABL is not required for BCR-ABL transformation
-
Heaney C., et al. Direct binding of CRKL to BCR-ABL is not required for BCR-ABL transformation. Blood 89 (1997) 297-306
-
(1997)
Blood
, vol.89
, pp. 297-306
-
-
Heaney, C.1
-
34
-
-
0034652159
-
Regulated expression of P210 BCR-ABL during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate
-
Era T., and Witte O.N. Regulated expression of P210 BCR-ABL during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate. Proc. Natl. Acad. Sci. U S A 97 (2000) 1737-1742
-
(2000)
Proc. Natl. Acad. Sci. U S A
, vol.97
, pp. 1737-1742
-
-
Era, T.1
Witte, O.N.2
-
35
-
-
0027280685
-
ABL oncogenes directly stimulate two distinct target cells in bone marrow from 5-fluorouracil-treated mice
-
Kelliher M.A., et al. ABL oncogenes directly stimulate two distinct target cells in bone marrow from 5-fluorouracil-treated mice. Oncogene 8 (1993) 1249-1256
-
(1993)
Oncogene
, vol.8
, pp. 1249-1256
-
-
Kelliher, M.A.1
-
36
-
-
0023410428
-
In vitro transformation of immature hematopoietic cells by the P210 bcr/abl oncogene product of the Philadelphia chromosome
-
McLaughlin J., et al. In vitro transformation of immature hematopoietic cells by the P210 bcr/abl oncogene product of the Philadelphia chromosome. Proc. Natl. Acad. Sci. U S A 84 (1987) 6558-6562
-
(1987)
Proc. Natl. Acad. Sci. U S A
, vol.84
, pp. 6558-6562
-
-
McLaughlin, J.1
-
37
-
-
3442885379
-
Effect of mutational inactivation of tyrosine kinase activity on BCR-ABL-induced abnormalities in cell growth and adhesion in human hematopoietic progenitors
-
Ramaraj P., et al. Effect of mutational inactivation of tyrosine kinase activity on BCR-ABL-induced abnormalities in cell growth and adhesion in human hematopoietic progenitors. Cancer Res. 64 (2004) 5322-5331
-
(2004)
Cancer Res.
, vol.64
, pp. 5322-5331
-
-
Ramaraj, P.1
-
38
-
-
0035871781
-
A model of human p210(bcr/ABL)-mediated chronic myelogenous leukemia by transduction of primary normal human CD34(+) cells with a BCR-ABL- containing retroviral vector
-
Zhao R.C., et al. A model of human p210(bcr/ABL)-mediated chronic myelogenous leukemia by transduction of primary normal human CD34(+) cells with a BCR-ABL- containing retroviral vector. Blood 97 (2001) 2406-2412
-
(2001)
Blood
, vol.97
, pp. 2406-2412
-
-
Zhao, R.C.1
-
39
-
-
0026362729
-
Human BCR-ABL gene has a lethal effect on embryogenesis
-
Heisterkamp N., et al. Human BCR-ABL gene has a lethal effect on embryogenesis. Transgenic Res. 1 (1991) 45-53
-
(1991)
Transgenic Res.
, vol.1
, pp. 45-53
-
-
Heisterkamp, N.1
-
40
-
-
0033762280
-
Consequences of BCR-ABL expression within the hematopoietic stem cell in chronic myeloid leukemia
-
Kabarowski J.H., and Witte O.N. Consequences of BCR-ABL expression within the hematopoietic stem cell in chronic myeloid leukemia. Stem Cells 18 (2000) 399-408
-
(2000)
Stem Cells
, vol.18
, pp. 399-408
-
-
Kabarowski, J.H.1
Witte, O.N.2
-
41
-
-
0025117392
-
Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome
-
Daley G.Q., et al. Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. Science 247 (1990) 824-830
-
(1990)
Science
, vol.247
, pp. 824-830
-
-
Daley, G.Q.1
-
42
-
-
0032533620
-
BCR-ABL efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: a novel model for chronic myelogenous leukemia
-
Zhang X., and Ren R. BCR-ABL efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: a novel model for chronic myelogenous leukemia. Blood 92 (1998) 3829-3840
-
(1998)
Blood
, vol.92
, pp. 3829-3840
-
-
Zhang, X.1
Ren, R.2
-
43
-
-
0032533257
-
Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow
-
Pear W.S., et al. Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow. Blood 92 (1998) 3780-3792
-
(1998)
Blood
, vol.92
, pp. 3780-3792
-
-
Pear, W.S.1
-
44
-
-
0033519238
-
The P190, P210, and P230 Forms of the BCR-ABL Oncogene Induce a Similar Chronic Myeloid Leukemia-like Syndrome in Mice but Have Different Lymphoid Leukemogenic Activity
-
Li S., et al. The P190, P210, and P230 Forms of the BCR-ABL Oncogene Induce a Similar Chronic Myeloid Leukemia-like Syndrome in Mice but Have Different Lymphoid Leukemogenic Activity. J. Exp. Med. 189 (1999) 1399-1412
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1399-1412
-
-
Li, S.1
-
45
-
-
19944426030
-
Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis
-
Koschmieder S., et al. Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis. Blood 105 (2005) 324-334
-
(2005)
Blood
, vol.105
, pp. 324-334
-
-
Koschmieder, S.1
-
46
-
-
0035052161
-
Retroviral Transduction Models of Ph+ Leukemia: Advantages and Limitations for Modeling Human Hematological Malignancies in Mice
-
Van Etten R.A. Retroviral Transduction Models of Ph+ Leukemia: Advantages and Limitations for Modeling Human Hematological Malignancies in Mice. Blood Cells Mol. Dis. 27 (2001) 201-205
-
(2001)
Blood Cells Mol. Dis.
, vol.27
, pp. 201-205
-
-
Van Etten, R.A.1
-
47
-
-
0028385758
-
Versatile retroviral vectors for potential use in gene therapy
-
Hawley R.G., et al. Versatile retroviral vectors for potential use in gene therapy. Gene Ther. 1 (1994) 136-138
-
(1994)
Gene Ther.
, vol.1
, pp. 136-138
-
-
Hawley, R.G.1
-
48
-
-
0035839842
-
Modeling Philadelphia chromosome positive leukemias
-
Wong S., and Witte O.N. Modeling Philadelphia chromosome positive leukemias. Oncogene 20 (2001) 5644-5659
-
(2001)
Oncogene
, vol.20
, pp. 5644-5659
-
-
Wong, S.1
Witte, O.N.2
-
49
-
-
0035525787
-
Establishment of a murine model for therapy-treated chronic myelogenous leukemia using the tyrosine kinase inhibitor STI571
-
Wolff N.C., and Ilaria Jr. R.L. Establishment of a murine model for therapy-treated chronic myelogenous leukemia using the tyrosine kinase inhibitor STI571. Blood 98 (2001) 2808-2816
-
(2001)
Blood
, vol.98
, pp. 2808-2816
-
-
Wolff, N.C.1
Ilaria Jr., R.L.2
-
50
-
-
2442465000
-
Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia
-
Hu Y., et al. Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia. Nat. Genet. 36 (2004) 453-461
-
(2004)
Nat. Genet.
, vol.36
, pp. 453-461
-
-
Hu, Y.1
-
51
-
-
85014195943
-
Elucidating critical mechanisms of deregulated stem cell turnover in the chronic phase of chronic myeloid leukemia
-
Holyoake T.L., et al. Elucidating critical mechanisms of deregulated stem cell turnover in the chronic phase of chronic myeloid leukemia. Leukemia 16 (2002) 549-558
-
(2002)
Leukemia
, vol.16
, pp. 549-558
-
-
Holyoake, T.L.1
-
52
-
-
0039970000
-
Chronic myelogenous leukemia and related disorders
-
Beutler E., et al. (Ed), McGraw-Hill
-
Lichtman M. Chronic myelogenous leukemia and related disorders. In: Beutler E., et al. (Ed). Williams Helatology (1995), McGraw-Hill 298-324
-
(1995)
Williams Helatology
, pp. 298-324
-
-
Lichtman, M.1
-
53
-
-
0346374772
-
Hematopoietic stem cells in chronic myeloid leukemia
-
Petzer A.L., and Gunsilius E. Hematopoietic stem cells in chronic myeloid leukemia. Arch. Med. Res. 34 (2003) 496-506
-
(2003)
Arch. Med. Res.
, vol.34
, pp. 496-506
-
-
Petzer, A.L.1
Gunsilius, E.2
-
54
-
-
19944385935
-
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors
-
Huntly B.J., et al. MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors. Cancer Cell 6 (2004) 587-596
-
(2004)
Cancer Cell
, vol.6
, pp. 587-596
-
-
Huntly, B.J.1
|