Transient change in GABAA receptor subunit mRNA expression in Lurcher cerebellar nuclei during Purkinje cell degeneration

BMC Neuroscience

Volumn 7, Issue , 2006, Pages

  Linnemann, Christoph ^a   Schmeh, Isabella ^a   Thier, P ^a   Schwarz, Cornelius ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CORTICOSTERONE; IODINE 125; MESSENGER RNA; RECEPTOR SUBUNIT;

ANIMAL CELL; ARTICLE; CEREBELLUM NUCLEUS; CONTROLLED STUDY; DEAFFERENTATION; DOWN REGULATION; FEMALE; FOREBRAIN; HETEROZYGOSITY; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL DEGENERATION; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROTRANSMISSION; NONHUMAN; PROTEIN EXPRESSION; PURKINJE CELL; RADIOIMMUNOASSAY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNAPSE;

AGING; ANIMALS; ANIMALS, NEWBORN; CEREBELLAR NUCLEI; COMPUTER SYSTEMS; DOWN-REGULATION; GENE EXPRESSION; MICE; MICE, NEUROLOGIC MUTANTS; NERVE DEGENERATION; PROTEIN ISOFORMS; PURKINJE CELLS; RECEPTORS, GABA-A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS;

EID: 33747334039     PISSN: 14712202     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-7-59     Document Type: Article

References (43)

1. Phillips RJS: "Lurcher", new gene in the linkage group XI of the house mouse. J Genet 1960, 57:35-42.
2. Caddy KW, Biscoe TJ: Structural and quantitative studies on the normal C3H and Lurcher mutant mouse. Phil Trans R Soc Lond B 1979, 287:167-201.
3. Wetts R, Herrup K: Interaction of granule, Purkinje and inferior olivary neurons in Lurcher chimaeric mice. I. Qualitative studies. J Embryol Exp Morphol 1982, 68:87-98.
4. Wetts R, Herrup K: Interaction of granule, Purkinje and inferior olivary neurons in lurcher chimeric mice. II. Granule cell death. Brain Res 1982, 250:358-362.
5. Zuo J, De Jager PL, Takahashi KA, Jiang W, Linden DJ, Heintz N: Neurodegeneration in Lurcher mice caused by mutation in δ 2 glutamate receptor gene. Nature 1997, 388:769-773.
6. Yang N, Horn R: Evidence for voltage-dependent S4 movement in sodium channels. Neuron 1995, 15:213-218.
7. Dumesnil-Bousez N, Sotelo C: Early development of the Lurcher cerebellum: Purkinje cell alterations and impairment of synaptogenesis. J Neurocytol 1992, 21:506-529.
8. Heckroth JA: Quantitative morphological analysis of the cerebellar nuclei in normal and lurcher mutant mice. I. Morphology and cell number. J Comp Neurol 1994, 343:173-182.
9. Sultan F, König T, Möck M, Thier P: Quantitative organization of neurotransmitters in the deep cerebellar nuclei of the Lurcher mutant. J Comp Neurol 2002, 452:311-323.
10. Lalonde R, Botez MI, Joyal CC, Caumartin M: Motor abnormalities in lurcher mutant mice. Physiol Behav 1992, 51:523-525.
11. Lalonde R. Motor learning in lurcher mutant mice. Brain Res 1994, 639:351-353.
12. Le Marec N, Caston J, Lalonde R: Impaired motor skills on static and mobile beams in lurcher mutant mice. Exp Brain Res 1997, 116:131-138.
13. Le Marec N, Lalonde R: Sensorimotor learning and retention during equilibrium tests in Purkinje cell degeneration mutant mice. Brain Res 1997, 768:310-316.
14. Le Marec N, Lalonde R: Treadmill performance of mice with cerebellar lesions: I. Purkinje cell degeneration mutant mice. Behav Neurosci 1998, 112:225-232.
15. Porras-Garcia E, Cendelin J, Dominguez-del-Toro E, Vozeh F, Delgado-Garcia JM: Purkinje cell loss affects differentially the execution, acquisition and prepulse inhibition of skeletal and facial motor responses in Lurcher mice. Eur J Neurosci 2005, 21:979-988.
16. Caston J, Vasseur F, Stelz T, Chianale C, Delhaye-Bouchaud N, Mariani J: Differential roles of cerebellar cortex and deep cerebellar nuclei in the learning of the equilibrium behavior: studies in intact and cerebellectomized lurcher mutant mice. Brain Res Dev Brain Res 1995, 86:311-316.
17. Lalonde R, Joyall CC, Guastavino J-M, Botez MI: Hole poking and motor coordination in lurcher mutant mice. Physiol Behav 1993, 54:41-44.
18. Lalonde R, Joyal CC, Côte C, Botez MI: Simultaneous visual discrimination learning in lurcher mutant mice. Brain Res 1993, 618:19-22.
19. Hilber P, Jouen F, Delhaye-Bouchaud N, Mariani J, Caston J: Differential roles of cerebellar cortex and deep cerebellar nuclei in learning and retention of a spatial task: studies in intact and cerebellectomized lurcher mutant mice. Behav Genet 1998, 28:299-308.
20. Caston J, Vasseur F, Delhaye-Bouchaud N, Mariani J: Delayed spontaneous alternation in intact and cerebellectomized control and lurcher mutant mice: differential role of cerebellar cortex and deep cerebellar nuclei. Behav Neurosci 1997, 111:214-218.
21. A-receptor-mediated conductance in cerebellar nuclei neurons in close temporal relationship to Purkinje cell death. J Neurophysiol 2004, 91:1102-1107.
22. A channel subtypes. Mol Neurobiol 1998, 18:35-86.
23. A-receptor subtypes during postnatal development: An immunohistochemical study. J Neurosci 1994, 14:5302-5324.
24. Gutensohn W, Guroff G: Hypoxanthine-guanine-phosphoribosyltransferase from rat brain (purification, kinetic properties, development and distribution). J Neurochem 1972, 19:2139-2150.
25. Brosh S, Sperling O, Bromberg Y, Sidi Y: Developmental changes in the activity of enzymes of purine metabolism in rat neuronal cells in culture and in whole brain. J Neuruchem 1990, 54:1776-1781.
26. Frederic F, Chautard T, Brochard R, Chianale C, Wollman E, Oliver C, Delhaye-Bouchaud N, Mariani J: Enhanced endocrine response to novel environment stress and endotoxin in Lurcher mutant mice. Neuroendocrinology 1997, 66:341-347.
27. Hilber P, Lorivel T, Delarue C, Caston J: Stress and anxious-related behaviors in Lurcher mutant mice. Brain Res 2004, 1003:108-112.
28. Teschemacher A, Zeise ML, Zieglgänsberger W: Corticosterone-induced decrease of inhibitory postsynaptic potential in rat hippocampal pyramidal neurons in vitro depends on cytosolic factors. Neurosci Lett 1996, 215:83-86.
29. A Receptors: Regulation by Corticosterone. J Neurosci 2001, 21:330-339.
30. Stone DJ, Walsh JP, Sebro R, Stevens R, Pantazopolous H, Benes FM: Effects of pre- and postnatal corticosterone exposure on the rat hippocampal GABA system. Hippocampus 2001, 11:492-507.
31. A/ benzodiazepine receptor gamma 2 subunit gene expression in developing normal and mutant mouse cerebellum. Brain Res Mol Brain Res 1993, 19:9-21.
32. A receptors depend upon subunit composition. Neuron 1990, 4:919-928.
33. A receptors containing gamma 2 or delta subtypes expressed with alpha 1 and beta 3 subtypes in mouse L929 cells. J Physiol 1997, 505:283-297.
34. Neelands TR, Macdonald RL: Incorporation of the pi subunit into functional gamma-aminobutyric Acid(A) receptors. Mol Pharmacol 1999, 56:598-610.
35. A receptors from mice lacking the gamma 2 subunit. J Physiol 2000, 527:111-131.
36. A receptor composition is determined by distinct assembly signals within α and β subunits. J Biol Chem 2003, 278:4747-4755.
37. Connolly CN, Wooltorton JRA, Smart TG, Moss SJ: Subcellular localization of β-aminobutyric acid type A receptors is determined by receptor B subunits. Proc Natl Acad Sci USA 1996:9899-9904.
38. Connolly CN, Kittler JT, Thomas P, Uren JM, Brandon NJ, Smart TG, Moss SJ: Cell surface stability of γ-aminobutyric acid type A receptors. Dependence on protein kinase C activity and subunit composition. J Biol Chem 1999, 274:36565-36572.
39. A receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J Neurosci 2000, 20:7972-7977.
40. Moss SJ, Smart TG: Constructing inhibitory synapses. Nat Rev Neurosci 2001, 2:240-250.
41. A receptor subunits expression with the properties of IPSCs in the developing thalamus. J Neurosci 2000, 20:2202-2208.
42. A receptor regulates inhibitory synaptic strength. J Neurophysiol 2004, 92:1718-1727.
43. A receptor subunits in the rat CNS. J Comp Neurol 1992, 326:193-216.