SHP-2-Erk signaling regulates Concanavalin A-dependent production of TIMP-2

Biochemical and Biophysical Research Communications

Volumn 348, Issue 3, 2006, Pages 1145-1149

  Helal Uddin Biswas, Md ^a   Hasegawa, Hitoki Hitoki ^a   Aminur Rahman, M ^a   Huang, Pengyu ^a   Mon, Naing Naing ^a   Ruhul Amin, A R M ^a   Senga, Takeshi ^a   Kannagi, Reiji ^b   Hamaguchi, Michinari ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b AICHI CANCER CENTER HOSPITAL   (Japan)

Author keywords

Concanavalin A; MAPK pathway; MMP 2; SHP 2; Signaling; TIMP 2

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; AMINO ACID; CONCANAVALIN A; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN INHIBITOR; PROTEIN TYROSINE PHOSPHATASE SHP 2; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL CELL; ARTICLE; CELL LINE; CELL MUTANT; FIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WILD TYPE;

CELLS, CULTURED; CONCANAVALIN A; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE KINASE 1; PROTEIN-TYROSINE-PHOSPHATASE; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 33747176812     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.07.173     Document Type: Article

References (26)

1. Stetler-Stevenson W.G., Krutzsch H.C., Wacher M.P., Margulies I.M.K., and Liotta L.A. The activation of human type IV collagenase proenzyme: sequence identification of the major conversion product following organomercurial activation. J. Biol. Chem. 264 (1989) 1353-1356
2. Butler G.S., Butler M.J., Atkinson S.J., Will H., Tamura T., Westrum S.S.V., Crabbe T., Clements J., d'Ortho M.P., and Murphy G. The TIMP-2 membrane type 1 metalloproteinase "Receptor" regulates the concentration and efficient activation of progelatinase-A. J. Biol. Chem. 273 (1998) 871-880
3. Jo Y., Yeon J., Kim H.J., and Lee S.T. Analysis of tissue inhibitor of metalloproteinase-2 effect on pro-matrix metalloproteinase-2 activation by membrane-type 1 matrix metalloproteinase using baculovious/insect-cell expression system. Biochem. J. 345 (2000) 3511-3519
4. Hayakawa T., Yamashita K., Ohuchi E., and Shinagawa A. Cell growth-promoting activity of tissue inhibitor of metalloproteinase-2 (TIMP-2). J. Cell Sci. 107 (1994) 2373-2379
5. Hayakawa T. Multiple functions of tissue inhibitors of metalloproteinases (TIMPs): a new aspect involving osteoclastic bone resorption. J. Bone Miner. Metab. 20 (2002) 1-13
6. Yamashita K., Suzuki M., Iwata H., Koike T., Hamaguchi M., Shinagawa A., Noguchi T., and Hayakawa T. Tyrosine phosphorylation is critical for growth signaling by tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2). FEBS Lett. 396 (1996) 103-107
7. Valente P., Fassina G., Melchiori A., Masiello L., Cilli M., Vacca A., Onisto M., Santi L., Stetler-Stevension W.G., and Albini A. TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis. Int. J. Cancer 75 (1998) 246-253
8. Cantemir V., Cai D.H., Reedy M.V., and Brauer P.R. Tissue inhibitor of metalloproteinase-2 (TIMP-2) expression during cardiac neural cell migration and its role in pro-MMP-2 activation. Dev. Dyn. 231 (2004) 709-719
9. Chang H., Lee J., Poo H., Noda M., Diaz T., Wei B., Stetler-Stevension W.G., and Oh J. TIMP-2 promotes cell spreading and adhesion via up regulation of Rap1 signaling. Biochem. Biophys. Res. Commun. 345 (2006) 1201-1206
10. Perez-Martinez L., and Jaworski D.M. Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal. J. Neurosci. 25 20 (2005) 4917-4929
11. Overall C.M., and Sodek J. Concanavalin A produces a matrix-degradative phenotype in human fibroblasts: induction and endogenous activation of collagenese, 72-kDa Gelatinase, and Pump-1 is accompanied by the suppression of the tissue inhibitor of matrix metalloproteinase. J. Biol. Chem. 265 (1990) 21141-21151
12. Thant A.A., Serbulea M., Kikkawa F., Liu E., Tomoda Y., and Hamaguchi M. c-Ras is required for the activation of the matrix metalloproteinases by Concanavalin A in 3Y1 cells. FEBS Lett. 406 (1997) 28-30
13. Sein T.T., Thant A.A., Hiraiwa Y., Amin A.R.M.R., Sohara Y., Liu Y., Matsuda S., Yamamoto T., and Hamaguchi M. A role for FAK in the Concanavalin A-dependent secretion of matrix metalloproteinase-2 and -9. Oncogene 19 (2000) 5539-5542
14. Amin A.R.M.R., Oo M.L., Senga T., Suzuki N., Feng G.S., and Hamaguchi M. SH2 domain containing protein tyrosine phosphatase-2 regulates Concanavalin-A-dependent secretion and activation of matrix metalloproteinase-2 via the extracellular signal-regulated kinase and p38 pathways. Cancer Research 63 (2003) 6334-6339
15. Freeman R.M., Plutzky Jr. J., and Neel B.G. Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew. Proc. Natl. Acad. Sci. USA 89 (1992) 11239-11243
16. Feng G.S. SHP-2 tyrosine phosphatase: signaling one cell or many. Exp. Cell Res. 253 (1999) 47-54
17. Wu C.J., O'Rourke D.M., Feng G.S., Johnson G.R., Wang Q., and Greene M.I. The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol-3-kinase/Akt activation by growth factors. Oncogene 20 (2001) 6018-6025
18. Hakak Y., and Martin S. Cas mediates transcriptional activation of the serum response element by Src. Mol. Cell. Biol. 19 (1999) 6953-6962
19. You M., Flick L.M., Yu D., and Feng G.S. Modulation of the nuclear factor κ B pathway by shp-2 tyrosine phosphatase in mediating the induction of interleukin (IL)-6 by IL-1 or tumor necrosis factor. J. Exp. Med. 193 (2001) 101-110
20. Hamaguchi M., Matsuyoshi N., Ohnishi Y., Gotoh B., Takeichi M., and Nagai Y. p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system. EMBO J. 12 (1993) 307-314
21. Liu E., Thant A.A., Kikkawa F., Kurata H., Tanaka S., Nawa A., Mizutani S., Matsuda S., Hanafusa H., and Hamaguchi M. The Ras-mitogen activated protein kinase pathway is critical for the activation of matrix metalloproteinase secretion and invasiveness in v-Crk-transformed 3Y1. Cancer Res. 60 (2000) 2361-2364
22. Thant A.A., Sein T.T., Liu E., Machida K., Kikkawa F., Koike T., Seiki M., Matsuda S., and Hamaguchi M. Ras pathway is required for the activation of MMP-2 secretion and for the invasion of Src-transformed 3Y1. Oncogene 18 (1999) 6555-6563
23. English J.L., Kassiri Z., Koskivirta I., Atkinson S., Grappa M.D., Soloway P.D., Nagase H., Vuorio E., Murphy G., and Khokha R. Individual Timp deficiencies differentially impact pro-MMP-2 activation. J. Biol. Chem. 281 (2006) 10337-10346
24. Jaworski D.M., Soloway P., Caterina J., and Falls W.A. Tissue inhibitor of metalloproteinase-2 (TIMP-2) deficient mice display motor deficient. J. Neurobiol. 66 (2000) 82-94
25. Jiang Y., Goldberg I.D., and Shi Y.E. Complex role of tissue inhibitors metalloproteinases in cancer. Oncogene 21 (2002) 2245-2252
26. Coussens L.M., and Werb Z. Matrix metalloproteinases and the development of cancer. Chem. Biol. 3 (1996) 895-904