Determination of drug plasma protein binding by solid phase microextraction

Journal of Pharmaceutical Sciences

Volumn 95, Issue 8, 2006, Pages 1712-1722

  Musteata, Florin Marcel ^a   Pawliszyn, Janusz ^a   Qian, Mark G ^b   Wu, Jing Tao ^b   Miwa, Gerald T ^b  

^a UNIVERSITY OF WATERLOO   (Canada)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

Albumin; Alpha 1 acid glycoprotein; Drug transport; HPLC; Human plasma; Mass spectrometry; pH shift; Protein binding; Solid phase microextraction

Indexed keywords

CAFFEINE; DIMETICONE; IBUPROFEN; PLASMA PROTEIN; POLYPYRROLE; PROPRANOLOL; VERAPAMIL; WARFARIN;

ARTICLE; BLOOD PH; CONTROLLED STUDY; DRUG BINDING; HUMAN; INTERMETHOD COMPARISON; IONIC STRENGTH; LIQUID CHROMATOGRAPHY; PLASMA PROTEIN BINDING; REPRODUCIBILITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 33747174872     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20558     Document Type: Review

References (39)

1. Kariv I, Cao H, Oldenburg KR. 2001. Development of a high throughput equilibrium dialysis method. J Pharm Sci 90:580-587.
2. Banker MJ, Clark TH, Williams JA. 2003. Development and validation of a 96-well equilibrium dialysis apparatus for measuring plasma protein binding. J Pharm Sci 92:967-974.
3. Sarre S, Van Belle K, Smolder sI, Krieken G, Michotte Y. 1992. The use of microdialysis for the determination of plasma protein binding of drugs. J Pharm Biomed Anal 10:735-739.
4. Olson RE, Christ DD. 1996. Plasma protein binding of drugs. Annu Rep Med Chemistry 31:327-336.
5. Blodgett J, Lynch J. 2003. MultiScreen filter assembly with ultracel-PPB membrane. Millipore Application Note AN1732EN00.
6. Smith QR, Fisher C, Allen DD. 2001. Blood-brain barrier: drug delivery and brain physiology. Proceedings of the OHOLO Conference on Blood-Brain Barrier, 44th, Israel, p 311-321.
7. Tanaka H, Mizojiri K. 1999. Drug-protein binding and blood-brain barrier permeability. J Pharmacol Exp Ther 288:912-918.
8. Fung EN, Chen Y-H, Lau YY. 2003. Semi-automatic high-throughput determination of plasma protein binding using a 96-well plate filtrate assembly and fast liquid chromatography-tandem mass spectrometry. J Chromat B 795:187-194.
9. Cheng Y, Ho E, Subramanyam B, Tseng J-L. 2004. Measurements of drug-protein binding by using immobilized human serum albumin liquid chromatography-mass spectrometry. J Chrom B 809:67-73.
10. Klotz IM. 1997. Ligand-receptor energetics: A guide for the Perplexed, ed. New York: Wiley. 170p.
11. Oravcova J, Bohs B, Lindner W. 1996. Drug-protein binding sites. New trends in analytical and experimental methodology. J Chrom B 677:1-28.
12. Ostergaard J, Schou C, Larsen C, Heegaard Niels HH. 2002. Evalution of capillary electrophoresis-frontal analysis for the study of low molecular weight drug-human serum albumin interactions. Electrophoresis 23:2842-2853.
13. Wright JD, Boudinot FD, Ujhelyi MR. 1996. Measurement and analysis of unbound drug concentrations. Clin Pharmacokinet 30:445-462.
14. Buchholz L, Cai C-H, Andress L, Cleton A, Brodfuehrer J, Cohen L. 2002. Evaluation of the human serum albumin column as a discovery screening tool for plasma protein binding. Eur J Pharm Sci 15:209-215.
15. Liu H, Sabus C, Carter GT, Tischler M. 2002. Use of a linear gradient flow program for liquid chromatography-mass spectrometry protein-binding studies. J Chrom A 955:237-243.
16. Nilsson M, Harang V, Bergstrom M, Ohlson S, Isaksson R, Johansson G. 2004. Determination of protein-ligand affinity constants from direct migration time in capillary electrophoresis. Electrophoresis 25:1829-1836.
17. Ishihama Y, Miwa T, Asakawa N. 2002. Drug-plasma protein binding assay by electrokinetic chromatography-frontal analysis. Electrophoresis 23:951-955.
18. Schuhmacher J, Buhner K, Witt-Laido A. 2000. Determination of the free fraction and relative free fraction of drugs strongly bound to plasma proteins. J Pharm Sci 89:1008-1021.
19. Schuhmacher J, Kohlsdorfer C, Buehner K, Brandenburger T, Kruk R. 2004. High-throughput determination of the free fraction of drugs strongly bound to plasma proteins. J Pharm Sci 93:816-830.
20. Koster EHM, Wemes C, Morsink JB, de Jong GJ. 2000. Determination of lidocaine in plasma by direct solid-phase microextraction combined with gas chromatography. J Chrom B 739:175-182.
21. Krogh M, Johansen K, Tonnesen F, Rasmussen KE. 1995. Solid-phase microextraction for the determination of the free concentration of valproic acid in human plasma by capillary gas chromatography. J Chrom B 673:299-305.
22. Vaes WHJ, Ramos EU, Verhaar HJM, Seinen W, Hermens JLM. 1996. Measurement of the free concentration using solid-phase microextraction: binding to protein. Anal Chem 68:4463-4467.
23. Yuan H, Pawliszyn J. 2001. Application of solid-phase microextraction in the determination of diazepam binding to human serum albumin. Anal Chem 73:4410-4416.
24. Pawliszyn J. 2003. Sample preparation: quo vadis? Anal Chem 75:2543-2558.
25. Pawliszyn J, editor. 1999. Applications of solid phase microextraction, ed. Cambridge, UK: Royal Soc Chem. 655p.
26. Pawliszyn J, editor. 2002. Comprehensive analytical chemistry, Vol. 37. Sampling and Sample Preparation for Field and Laboratory: fundamentals and new directions in sample preparation, ed. Amsterdam: Elsevier. 1131p.
27. Mullett WM, Pawliszyn J. 2002. Direct determination of benzodiazepines in biological fluids by restricted-access solid-phase microextraction. Anal Chem 74:1081-1087.
28. Musteata FM, Walles M, Pawliszyn J. 2005. Fast assay of angiotensin 1 from whole blood by cation-exchange restricted-access solid-phase microextraction. Anal Chim Acta 537:231-237.
29. Koster EHM, Crescenzi C, den Hoedt W, Ensing K, de Jong GJ. 2001. Fibers coated with molecularly imprinted polymers for solid-phase microextraction. Analytical Chemistry 73:3140-3145.
30. Guzman NA. 2003. Improved solid-phase microextraction device for use in on-line immunoaffinity capillary electrophoresis. Electrophoresis 24:3718-3727.
31. Yuan H, Mullett WM, Pawliszyn J. 2001. Biological sample analysis with immunoaffinity solid-phase microextraction. Analyst 126:1456-1461.
32. Musteata FM, Pawliszyn J. 2005. Study of ligand-receptor binding using SPME: investigation of receptor, free, and total ligand concentrations. J Proteome Res 4:789-800.
33. Lord HL, Grant RP, Walles M, Incledon B, Fahie B, Pawliszyn JB. 2003. Development and evaluation of a solid-phase microextraction probe for in vivo pharmacokinetic studies. Anal Chem 75:5103-5115.
34. Musteata FM, Pawliszyn J. 2005. Assay of stability, free and total concentration of chlorhexidine in saliva by solid phase microextraction. J Pharm Biomed Anal 37:1015-1024.
35. Fur a A, Harper TW, Zhang H, Fung L, Shyu WC. 2003. Shift in pH of biological fluids during storage and processing: effect on bioanalysis. J Pharm Biomed Anal 32:513-522.
36. Hardman JG, Limbird LE, Gilman AG, Goodman LS, editors. 2001. Goodman and Gilman's the pharmacological basis of therapeutics, 10th ed. New York: McGraw-Hill, 2148p.
37. Paliwal JK, Smith DE, Cox SR, Berardi RR, Dunn-Kucharski VA, Elta GH. 1993. Stereoselective, competitive, and nonlinear plasma protein binding of ibuprofen enantiomers as determined in vivo in healthy subjects. J Pharm Biopharm 21:145-161.
38. Johnson JA, Lingston TN. 1997. Differences between blacks and whites in plasma protein binding of drugs. Eur J Clin Pharmacol 51:485-488.
39. Blanchard J. 1982. Protein binding of caffeine in young and elderly males. J Pharm Sci 71:1415-1418.