Determination of protein-ligand affinity constants from direct migration time in capillary electrophoresis

Electrophoresis

Volumn 25, Issue 12, 2004, Pages 1829-1836

  Nilsson, Mikael ^a   Harang, Valerie ^b,c   Bergström, Maria ^a   Ohlson, Sten ^a   Isaksson, Roland ^a   Johansson, Gunnar ^b  

^a LINNAEUS UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

Capillary electrophoresis; Cellobiohydrolase; Dissociation constant; Enantiomer; Migration time; Partial filling; 1 acid glycoprotein

Indexed keywords

CAPILLARY ELECTROPHORESIS; DISSOCIATION; ELECTROOSMOSIS; FILLING; LIGANDS; PROTEINS;

AFFINITY CONSTANTS; CELLOBIOHYDROLASES; DETERMINATION OF PROTEINS; DISSOCIATION CONSTANT; LIGAND AFFINITY; MIGRATION TIME; PARTIAL FILLING; PROTEIN LIGANDS; SIMPLE METHOD; Α1-ACID GLYCOPROTEIN;

GLYCOPROTEINS;

CELLULASE; CHLORPHENIRAMINE; MEPIVACAINE; OROSOMUCOID; PROPRANOLOL;

ARTICLE; BINDING AFFINITY; CALCULATION; CAPILLARY ELECTROPHORESIS; CHIRALITY; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG STRUCTURE; ELECTRIC FIELD; ELECTROOSMOSIS; ELECTROPHORETIC MOBILITY; ENANTIOMER; IONIC STRENGTH; LINEAR SYSTEM; MEASUREMENT; MIGRATION; PROTEIN PROTEIN INTERACTION; SEPARATION TECHNIQUE; THEORETICAL STUDY; TIME;

EID: 3543034005     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/elps.200405918     Document Type: Article

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