Increased levels of serum S100B protein in critically ill patients without brain injury

Shock

Volumn 26, Issue 1, 2006, Pages 20-24

  Routsi, Christina ^a,b   Stamataki, Elisabeth ^b   Nanas, Seraphim ^a   Psachoulia, Christina ^b   Stathopoulos, Anastasios ^b   Koroneos, Apostolos ^a   Zervou, Maria ^a   Jullien, Gerard ^b   Roussos, Charis ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b EVANGELISMOS HOSPITAL   (Greece)

Author keywords

Critically ill; Hemoglobin; Lactate; Mechanical ventilation; Oxygen content; S100B; Tissue hypoperfusion

Indexed keywords

HEMOGLOBIN; LACTIC ACID; PROTEIN S100B; BIOLOGICAL MARKER; NERVE GROWTH FACTOR; PROTEIN S 100; S 100 CALCIUM BINDING PROTEIN BETA SUBUNIT; S-100 CALCIUM-BINDING PROTEIN BETA SUBUNIT;

ADULT; AGED; ARTERIAL PRESSURE; ARTICLE; ARTIFICIAL VENTILATION; BLOOD GAS ANALYSIS; BRAIN INJURY; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CRITICALLY ILL PATIENT; DEPENDENT VARIABLE; DISEASE ASSOCIATION; FEMALE; HEMOGLOBIN BLOOD LEVEL; HOSPITAL ADMISSION; HUMAN; INDEPENDENT VARIABLE; INTENSIVE CARE UNIT; LACTATE BLOOD LEVEL; MALE; MULTIPLE ORGAN FAILURE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PH; PROTEIN BLOOD LEVEL; SCORING SYSTEM; TISSUE PERFUSION; ADOLESCENT; BLOOD; CRITICAL ILLNESS; HOSPITALIZATION; MIDDLE AGED;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BRAIN INJURIES; CRITICAL ILLNESS; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; NERVE GROWTH FACTORS; RESPIRATION, ARTIFICIAL; S100 PROTEINS; SEVERITY OF ILLNESS INDEX;

EID: 33747161910     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000209546.06801.d7     Document Type: Article

References (35)

1. Moore BW: A soluble protein characteristic of the nervous system. Biochem Biophys Res Commun 19:739-744, 1965.
2. Zimmer DB, Cornwall EH, Landar A, Song W: The S100 protein family: history, function, and expression. Brain Res Bull 37:417-429, 1995.
3. Donato R: S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int J Biochem Cell Biol 33:637-668, 2001.
4. Schafer BW, Heizmann CW: Ca2+ -binding S100 proteins in the central nervous system. Neurochem Res 24:1097-1100, 1999.
5. Petzold A, Green AJ, Keir G, Fairley S, Kitchen N, Smith M, Thompson EJ: Role of serum S100B as an early predictor of high intracranial pressure and mortality in brain injury: a pilot study. Crit Care Med 30:2705-2710, 2002.
6. Raabe A, Grolms C, Seifert V: Serum markers of brain damage and outcome prediction after severe head injury. Br J Neurosurg 13:56-59, 1999.
7. Ingebrigtsen T, Waterloo K, Jacobsen EA, Langbakk B, Romner B: Traumatic brain damage in minor head injury: relation of serum S100 protein measurements to magnetic resonance imaging and neurobehavioral outcome. Neurosurgery 45:468-476, 1999.
8. Mussack T, Biberthaler P, Kanz KG, Heckl U, Gruber R, Linsenmaier P, Mutschler W, Jochum M: Immediate S100B and neuron-specific enolase plasma measurements or rapid evaluation of primary brain damage in alcohol-intoxicated, minor head-injured patients. Shock 18:395-400, 2002.
9. Bottiger BW, Mobes S, Glatzer R, Bauer H, Gries A, Bartsch P, Motsch J, Martin E: Astroglial protein S100B is an early and sensitive marker of hypoxic brain damage and outcome after cardiac arrest in humans. Circulation 103:2694-2698, 2001.
10. Mussack T, Biberthaler P, Kanz KG, Wiedemann E, Gippner-Steppert C, Mutschler W, Jochum M: Serum S100B and interleukin-8 as predictive markers for comparative neurologic outcome analysis of patients after cardiac arrest and severe traumatic brain injury. Crit Care Med 30:2669-2674, 2002.
11. Shaaban Ali M, Harmer R: Serum S100 protein as a marker of cerebral damage during cardiac surgery. Br J Anaesth 85:287-298, 2000.
12. Jonsson H, Johnsson P, Alling C, Westaby S, Blomquist S: Significance of serum S100 release after coronary artery bypass grafting. Ann Thorac Surg 65:1639-1644, 1998.
13. Missler U, Wiesmann M, Friedrich C, Kaps M: S100 protein and neuron-specific enolase concentrations in blood as indicators of infarction volume and prognosis in acute ischemic stroke. Stroke 28:1956-1960, 1997.
14. Wiesmann M, Missler U, Hagenstrom H, Gottmann D: S-100 protein plasma levels after aneurysmal subarachnoid haemorrhage. Acta Neurochir (Wien) 139:1155-1160, 1997.
15. Snyder-Ramos SA, Gruhike T, Bauer H, Bauer M, Luntz AP, Motsch J, Martin E, Vahl CF, Missler U, Wiesmann M, et al: Cerebral and extracerebral release of protein S100B in cardiac surgical patients. Anesthesia 59:344-349, 2004.
16. Anderson RA, Hansson LO, Nilsson O, Liska J, Settergren G, Vaage J: Increase in serum S100A1-B and S100BB during cardiac surgery arises from extracerebral sources. Ann Thorac Surg 71:1512-1517, 2001.
17. Pelinka LE, Toegel E, Mauritz W, Redl H: Serum S100B: a marker of brain damage in traumatic brain injury with and without multiple trauma. Shock 19:195-200, 2003.
18. Anderson RE, Hansson LO, Nilson O, Dijlai-Merzong R, Settergren G: High serum S100B levels for trauma patients without head injuries. Neurosurgery 48:1255-1258, 2001.
19. Savola O, Pyhtinen J, Leino T, Sittonen S, Niemela O, Hllbom M: Effects of head and extracranial injuries on serum protein S100B levels in trauma patients. J Trauma 56:1229-1234, 2004.
20. Pelinka LE, Szalay L, Jafarmadar M, Schidhammer R, Redl H, Bahrami S: Circulated S100B is increased after bilateral femur fracture without brain injury in the rat. Br J Anaesth 91:595-597, 2003.
21. Pelinka LE, Bahrami S, Szalay L, Umar F, Redl H: Hemorrhagic shock induces an S100B increase associated with shock severity. Shock 19:422-426, 2003.
22. Vincent JL, De Mendonca A, Cantraine F, Moreno R, Takala J, Suter PM, Sprung CL, Colardyn F, Blecher S: Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units. Results of a multicenter, prospective study. Crit Care Med 26:1793-1800, 1998.
23. Murray JF, Matthay MA, Luce JM: An expanded definition of the adult respiratory distress syndrome. Am Rev Resp Dis 138:720-723, 1998.
24. Herbert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisir E: A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 340:409-417, 1999.
25. Tsao N, Hsu HP, Wu CM, Liu CC, Lei HY: TNFa causes an increase in bloodbrain barrier permeability during sepsis. J Med Microbiol 50:812-821, 2001.
26. Fries M, Bickenbach J, Henzler D, Beckers S, Dembinski R, Sellhaus B, Rossaint R, Kuhlen R: S-100 protein and neurohistopathologic changes in a porcine model of acute lung injury. Anesthesiology 102:761-767, 2005.
27. Otto M, Holthusen S, Bahn E, Sohnchen N, Wiltfang J, Geese R, Fischer A, Reimers CD: Boxing and running lead to a rise in serum levels of S100B protein. Int J Sports Med 21:551-555, 2000.
28. Dietrich MO, Tort AB, Schaf DV, Farina M, Goncalves CA, Souza D, Portela LV: Increase in serum S100B protein level after a swimming race. Can J Appl Physiol 28:710-716, 2003.
29. Scaccianoce S, Del Bianco P, Pannitteri G, Passarelli F: Relationship between stress and circulating levels of S100B protein. Brain Res 1004:208-211, 2004.
30. Plesnila N, Ringel F, Chang CC, Staub F, Baethmann A: Relevance of calcium homeostasis in glial cell swelling from acidosis. Acta Neurochir 71:S203-S205, 1998.
31. Staub F, Baethmann A, Peters J, Weigt H, Kempski O: Effects of lactacidosis on glial cell volume and viability. J Biol Chem 267:9684-9689, 1992.
32. Pelinka LE, Harada N, Szalay L, Jafarmadar M, Redi H, Bahrami S: Release of S100B differs during ischemia and reperfusion of the liver, the gut, and the kidney in rats. Shock 21:72-76, 2004.
33. Usui A, Kato K, Abe T, Murase M, Tanaka M, TackEuchi E: S100 protein in blood and urine during open-heart surgery. Clin Chem 35:1942-1944, 1989.
34. Jonsson H, Johnsson P, Hoglund P, Alling C, Blomquist S: Elimination of S100B and renal function after cardiac surgery. J Cardiothorac Vasc Anesth 14:698-701, 2000.
35. Strauss GI, Christiansen M, Moller K, Clemmesen JO, Larsen FS, Knudsen GM: S-100b and neuron-specific enolase in patients with fulminant hepatic failure. Liver Transpl 7:964-970, 2001.