Relevance of Calcium Homeostasis in Glial Cell Swelling from Acidosis

Acta Neurochirurgica, Supplement

Volumn 1998, Issue SUPPL. 71, 1998, Pages 203-205

  Plesnila, N ^a   Ringel, F ^a   Chang, R C C ^a   Staub, F ^b   Baethmann, Alexander ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b University of Munich ^*

Author keywords

Acidosis; Calcium homeostasis; Cytotoxic brain; Glial cell swelling

Indexed keywords

CALCIUM; CALCIUM CHANNEL;

ACID BASE BALANCE; ARTICLE; BRAIN TUMOR; CELL CULTURE; CELL DEATH; CELL SIZE; GLIA; GLIOMA; HOMEOSTASIS; HUMAN; LACTIC ACIDOSIS; METABOLISM; PATHOPHYSIOLOGY; PH; PHYSIOLOGY;

ACID-BASE EQUILIBRIUM; ACIDOSIS, LACTIC; BRAIN NEOPLASMS; CALCIUM; CALCIUM CHANNELS; CELL DEATH; CELL SIZE; GLIOMA; HOMEOSTASIS; HUMANS; HYDROGEN-ION CONCENTRATION; NEUROGLIA; TUMOR CELLS, CULTURED;

EID: 0032238806     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-6475-4_58     Document Type: Article

References (13)

1. Kachel V, Glossner E, Kordwig G, Ruhenstroth-Bauer G (1977) Fluvo-Metricell, a combined cell volume and cell fluorescence analyzer. J Histochem Cytochem 25: 804-812
2. Lohr JW, Yohe LA (1994) Mechanisms of hypoosmotic volume regulation in glioma cells. Brain Res 667: 263-268
3. Kempski O, Staub F, v Rosen F, Zimmer M, Neu A, Baethmann A (1988) Molecular mechanisms of glial swelling in vitro. Neurochem Pathol 9: 109-125
4. Kraig RP, Pulsinelli WA, Plum F (1985) Heterogenous distribution of hydrogen and bicarbonate ions during complete brain ischemia. In: Kogure K, Hossmann K-A, Siesjö BK, Welch FA (eds) Progress in brain research. Elsevier, Amsterdam
5. Kraig RP, Petito CK, Plum F, Pulsinelli WA (1987) Hydrogen ions kills brain at concentrations reached in ischemia. J Cereb Blood Flow Metab 7: 379-386
6. Kimelberg HK (1995) Current concepts of brain edema. Review of laboratory investigations. J Neurosurg 83: 1051-1059
7. McCarty NA, O'Neil RG (1992) Calcium signalling in cell volume regulation. Physiol Rev 72: 1037-1061
8. Neary JT, Fu Q, Bender AS, Norenberg MD (1993) Effect of external acidosis on basal and ATP-evoked calcium influx in cultured astrocytes. Brain Res 603: 211-216
9. 2+ transients evoked by lactic acid in cultured mammalian neurons. Am J Physiol 268: R506-R513
10. O'Connor E, Kimelberg HK (1993) Role of calcium in astrocyte volume regulation and in the release of ions and amino acids. J Neurosci 13: 2638-2650
11. Siesjö BK, Katsura K, Mellergard P, Ekholm A, Lundgren J, Smith M-L (1993) Acidosis-related brain damage. In: Kogure K, Hossmann K-A, Siesjö BK (eds) Progress in brain research. Elsevier, Amsterdam
12. Staub F, Baethmann A, Peters J, Weigt H, Kempski O (1990) Effects of lactacidosis on glial cell volume and viability. J Cereb Blood Flow Metab 10: 866-876
13. Staub F, Winkler A, Peters J, Kempski O, Kachel V, Baethmann A (1994) Swelling, acidosis, and irreversible damage of glial cells from exposure to arachidonic acid in vitro. J Cereb Blood Flow Metab 14: 1030-1039