Immediate S-100B and neuron-specific enolase plasma measurements for rapid evaluation of primary brain damage in alcohol-intoxicated, minor head-injured patients

Shock

Volumn 18, Issue 5, 2002, Pages 395-400

  Mussack, Thomas ^a   Biberthaler, Peter ^a   Kanz, Karl Georg ^a   Heckl, Ute ^a   Gruber, Rudolf ^a   Linsenmaier, Ulrich ^a   Mutschler, Wolf ^a   Jochum, Marianne ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Alcohol intoxication; Cerebral computed tomography; Minor head injury; NSE; ROC analysis; S 100B; Screening test; Traumatic brain injury

Indexed keywords

ALCOHOL; BIOLOGICAL MARKER; ENOLASE; NERVE GROWTH FACTOR; PROTEIN S 100; S 100 CALCIUM BINDING PROTEIN BETA SUBUNIT; S-100 CALCIUM-BINDING PROTEIN BETA SUBUNIT;

ADULT; AGED; ALCOHOL INTOXICATION; ARTICLE; BLOOD; BRAIN INJURY; CASE CONTROL STUDY; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; HEAD INJURY; HUMAN; MALE; MIDDLE AGED; ROC CURVE; VALIDATION STUDY;

ADULT; AGED; ALCOHOLIC INTOXICATION; BIOLOGICAL MARKERS; BRAIN INJURIES; CASE-CONTROL STUDIES; CRANIOCEREBRAL TRAUMA; ETHANOL; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE GROWTH FACTORS; PHOSPHOPYRUVATE HYDRATASE; ROC CURVE; S100 PROTEINS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0036835395     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-200211000-00002     Document Type: Article

References (36)

1. Raabe A, Grolms C, Keller M, Dohnert J, Sorge O, Seifert V: Correlation of computed tomography findings and serum brain damage markers following severe head injury. Acta Neurochir (Wien) 140:787-791, 1998.
2. Stein SC, Ross SE: The value of computed tomographic scans in patients with low-risk head injuries. Neurosurgery 26:638-640, 1990.
3. Murray GD, Teasdale GM, Braakman R, Cohadon F, Dearden M, Iannotti F, Karimi A, Lapierre F, Maas A, Ohman J, Persson L, Servadei F, Stocchetti N, Trojanowski T, Unterberg A: The European Brain Injury Consortium survey of head injuries. Acta Neurochir (Wien) 141:223-236, 1999.
4. Klauber MR, Marshall LF, Luerssen TG, Frankowski R, Tabaddor K, Eisenberg HM: Determinants of head injury mortality: importance of the low risk patient [see comments]. Neurosurgery 24:31-36, 1989.
5. Baethmann A, Chapuis D, Wirth A: System analysis of patient management during the pre- and early clinical phase in severe head injury. Acta Neurochir Suppl (Wien) 73:93-97, 1999.
6. Baethmann A, Lehr D, Wirth A: Prospective analysis of patient management in severe head injury. Acta Neurochir Suppl (Wien) 71:107-110, 1998.
7. Lehr D, Baethmann A, Reulen HJ, Steiger HJ, Lackner C, Stummer W, Wirth A, Holzel D, Stolpe E, Assal J, Belg A, Schrodel M, Muller N, Ueblacker P, Chlistalla A, Schneider G, Schweiberer L, Dietz HG, Trappe A, Gobel WE, Jaksche H, Messner V, Grumme T, Wenger P, Weess T: Management of patients with severe head injury in the preclinical phase: a prospective analysis. J Trauma 42:S71-S75, 1997.
8. Borczuk P: Predictors of intracranial injury in patients with mild head trauma. Ann Emerg Med 25:731-736, 1995.
9. Kelly DF: Alcohol and head injury: an issue revisited. J Neurotrauma 12:883-890, 1995.
10. Nagy KK, Joseph KT, Krosner SM, Roberts RR, Leslie CL, Dufty K, Smith RF, Barrett J: The utility of head computed tomography after minimal head injury. J Trauma 46:268-270, 1999.
11. Ingebrigtsen T, Romner B, Kongstad P, Langbakk B: Increased serum concentrations of protein S-100 after minor head injury: a biochemical serum marker with prognostic value? [letter]. J Neurol Neurosurg Psychiatry 59:103-104, 1995.
12. Raabe A, Seifert V: Fatal secondary increase in serum S-100B protein after severe head injury: report of three cases. J Neurosurg 91:875-877, 1999.
13. Rothoerl RD, Woertgen C, Holzschuh M, Metz C, Brawanski A: S-100 serum levels after minor and major head injury. J Trauma 45:765-767, 1998.
14. Biberthaler P, Mussack T, Wiedemann E, Kanz KG, Koelsch M, Gippner-Steppert C, Jochum M: Evaluation of S-100b as a specific marker for neuronal damage due to minor head trauma. World J Surg 25:93-97, 2001.
15. Mussack T, Biberthaler P, Wiedemann E, Kanz KG, Englert A, Gippner-Steppert C, Jochum M: S-100b as a screening marker of the severity of minor head trauma (MHT): a pilot study. Acta Neurochir Suppl 76:393-396, 2000.
16. Mussack T, Biberthaler P, Gippner-Steppert C, Kanz KG, Wiedemann E, Mutschler W, Jochum M: Early cellular brain damage and systemic inflammatory response after cardiopulmonary resuscitation or isolated severe head trauma: a comparative pilot study on common pathomechanisms. Resuscitation 49:193-199, 2001.
17. Pleines UE, Morganti-Kossmann MC, Rancan M, Joller H, Trentz O, Kossmann T: S-100β reflects the extent of injury and outcome, whereas neuronal-specific enolase is a better indicator of neuroinflammation in patients with severe traumatic brain injury. J Neurotrauma 18:491-498, 2001.
18. Haimoto H, Hosoda S, Kato K: Differential distribution of immunoreactive S100-α and S100-β proteins in normal non-nervous human tissues. Lab Invest 57:489-498, 1987.
19. Donato R: Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type. Biochim Biophys Acta 1450:191-231, 1999.
20. Fogel W, Krieger D, Veith M, Adams HP, Hund E, Storch-Hagenlocher B. Buggle F, Mathias D, Hacke W: Serum neuron-specific enolase as early predictor of outcome after cardiac arrest. Crit Care Med 25:1133-1138, 1997.
21. Ross SA, Cunningham RT, Johnston CF, Rowlands BJ: Neuron-specific enolase as an aid to outcome prediction in head injury. Br J Neurosurg 10: 471-476, 1996.
22. Marangos PJ, Schmechel DE: Neuron specific enolase, a clinically useful marker for neurons and neuroendocrine cells. Annu Rev Neurosci 10:269-295, 1987.
23. Woertgen C, Rothoerl RD, Holzschuh M, Metz C, Brawanski A: Comparison of serial S-100 and NSE serum measurements after severe head injury. Acta Neurochir (Wien) 139:1161-1164, 1997.
24. Herrmann M, Jost S, Kutz S, Ebert AD, Kratz T, Wunderlich MT, Synowitz H: Temporal profile of release of neurobiochemical markers of brain damage after traumatic brain injury is associated with intracranial pathology as demonstrated in cranial computerized tomography. J Neurotrauma 17:113-122, 2000.
25. Romner B, Ingebrigtsen T, Kongstad P, Borgesen SE: Traumatic brain damage: serum S-100 protein measurements related to neuroradiological findings. J Neurotrauma 17:641-647, 2000.
26. Haydel MJ, Preston CA, Mills TJ, Luber S, Blaudeau E, DeBlieux PM: Indications for computed tomography in patients with minor head injury [see comments]. N Engl J Med 343:100-105, 2000.
27. Biberthaler P, Mussack T, Wiedemann E, Gilg T, Soyka M, Koller G, Pfeifer KJ, Linsenmaier U, Mutschler W, Gippner-Steppert C, Jochum M: Elevated serum levels of S-100B reflect the extent of brain injury in alcohol intoxicated patients after mild head trauma. Shock 16:97-101, 2001.
28. Hammon JW Jr, Stump D: Commentary: biochemical markers of brain injury after cardiac surgery. J Thorac Cardiovasc Surg 119:130-131, 2000.
29. Griner PF, Mayewski RJ, Mushlin AI, Greenland P: Selection and interpretation of diagnostic tests and procedures: principles and applications. Ann Intern Med 94:557-592, 1981.
30. Brickley MR, Shepherd JP: The relationship between alcohol intoxication, injury severity and Glasgow Coma Score in assault patients. Injury 26:311-314, 1995.
31. Skogseid IM, Nordby HK, Urdal P, Paus E, Lilieaas F: Increased serum creatine kinase BB and neuron-specific enolase following head injury indicates brain damage. Acta Neurochir (Wien) 115:106-111, 1992.
32. Fassbender K, Schmidt R, Schreiner A, Fatar M, Muhlhauser F, Daffertshofer M, Hennerici M: Leakage of brain-originated proteins in peripheral blood: temporal profile and diagnostic value in early ischemic stroke. J Neurol Sci 148:101-105, 1997.
33. Wunderlich MT, Ebert AD, Kratz T, Goertler M, Jost S, Herrmann M: Early neurobehavioral outcome after stroke is related to release of neurobiochemical markers of brain damage. Stroke 30:1190-1195, 1999.
34. Johnsson P, Blomquist S, Luhrs C, Malmkvist G, Alling C, Solem JO, Stahl E: Neuron-specific enolase increases in plasma during and immediately after extracorporeal circulation. Ann Thorac Surg 69:750-754, 2000.
35. Zimmer DB, Cornwall EH, Landar A, Song W: The S100 protein family: history, function, and expression. Brain Res Bull 37:417-429, 1995.
36. Kahn HJ, Baumal R, Van Eldik LJ, Dunn RJ, Marks A: Immunoreactivity of S100β in heart, skeletal muscle, and kidney in chronic lung disease: possible induction by cAMP. Mod Pathol 4:698-701, 1991.