The antihypertensive activity of angiotensin-converting enzyme inhibitory peptide containing in bovine lactoferrin

Chinese Journal of Physiology

Volumn 49, Issue 2, 2006, Pages 67-73

  Lee, Nai Yuan ^a   Cheng, Juei Tang ^b   Enomoto, Toshiki ^c   Nakamura, Ichiro ^d  

^a Taiwan Livestock Research Institute   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c ISHIKAWA PREFECTURAL UNIVERSITY   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Angiotensin converting enzyme (ACE) inhibitory peptide; Bovine lactoferrin; Captopril; Spontaneously hypertensive rat

Indexed keywords

CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LACTOFERRIN; LEUCYLARGINYLPROLYLVALYLALANYLALANINE; PEPTIDE DERIVATIVE; PROTEIN HYDROLYSATE; UNCLASSIFIED DRUG; ANTIHYPERTENSIVE AGENT; PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; HYPERTENSION; IC 50; IN VITRO STUDY; MALE; NONHUMAN; PROTEIN HYDROLYSIS; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; ANIMAL; BLOOD PRESSURE; CATTLE; CHEMISTRY; DRUG EFFECT; PATHOPHYSIOLOGY; TREATMENT OUTCOME; WISTAR RAT;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERTENSION; LACTOFERRIN; PEPTIDES; RATS; RATS, INBRED SHR; RATS, WISTAR; TREATMENT OUTCOME;

EID: 33747099989     PISSN: 03044920     EISSN: 26660059     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Anderson, B.F., Baker, H.M., Norris, G.E., Rice, D.W. and Baker, E.N. Structure of human lactoferrin: crystallographic structure analysis and refinement at 2.8 A resolution. J. Mol. Biol. 209: 711-734, 1989.
2. Ariyoshi, Y. Angiotensin-converting enzyme inhibitors derived from food proteins. Trends Food Sci. Technol. 4: 139-143, 1993.
3. Bellamy, W., Mitsunori, T., Yamauchi, K., Wakabayashi, H., Kawase, K. and Tomita, M. Identification of the bactericidal domain of lactoferrin. Biochimica. et Biophysica. Acta. 1121: 130-136, 1992.
4. Bellamy, W.R., Wakabayashi, H., Takase, M., Kawase, K., Shimamura, S. and Tomita, M. Role of cell-binding in the antibacterial mechanism of Lactoferricin B. J. Appl. Bacteriol. 75: 478-484, 1993.
5. Brock, J.H. The physiology of lactoferrin. Biochem. Cell. Biol. 80: 1-6, 2002.
6. Byers, L.D. and Wolfenden, R. Binding of the by-product analog benzylsuccinic acid by carboxypeptidase A. Biochemistry 12: 2070-2078, 1973.
7. Case, D.B., Atlas, S.A., Laragh, J.H., Sealey, J.E., Sullivan, P.A. and Mckinstry, D.N. Clinical experience with blockade of the rennin-angiotension-aldosterone system by an oral convertingenzyme inhibitor (captopril) in hypertensive patients. Prog. Cardiovasc. Dis. 21: 195-206, 1978.
8. Choi, H.S., Cho, H.Y., Yang, H.C., Ra, K.S. and Suh, H.J. Angiotensin I-converting enzyme inhibitor from Grifola frondosa. Food Res. Int. 34: 177-182, 2001.
9. Cushman, D.W. and Cheung, H.S. Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung. Biochem. Phamacol. 20: 1637-1648, 1971.
10. Ehlers, M.R. and Riordan, J.F. Angiotensin-converting enzyme new concepts converting its biological role. Biochemistry 28: 5311-5317, 1989.
11. Fiat, A.M., Daniele, M.S. and Pierre, J. Biological active peptides from milk proteins with emphasis on two examples concerning antithrombotic and immunomodulating activities. J. Dairy Sci. 76: 301-310, 1993.
12. Gohlke, P., Linz, W., Schokens, B.A., Kuwer, I., Bartenbach, S. and Chell, A. Angiotensin converting enzyme inhibition improves cardiac function. Hypertension 26: 411-418, 1994.
13. Greene, A.S. and Amaral, S.L. Microvascular angiogenesis and the renin-angiotensin system. Curr. Hypertens. Rep. 4: 56-62, 2002.
14. Kim, S.K., Bynn, H.G., Park, P.J. and Shahidi, F. Angiotensin I converting enzyme inhibitory peptides purified from bovine skin gelatin hydrolysate. J. Agric. Food Chem. 49: 2992-2997, 2001.
15. Kohama, Y., Matsumoto, S., Oka, H., Teramoto, T., Okabe, M. and Mimura, T. Isolation of angiotensin-converting enzyme inhibitor from tuna muscle. Biochem. Biophys. Res. Commun. 155: 332-337, 1988.
16. Kohmura, M., Nio, N., Kubo, K., Minoshima, Y., Munekata, E. and Ariyoshi, Y. Inhibition of angiotensin-converting enzyme by synthetic peptide fragments of human β-casein. Agric. Biol. Chem. 53: 2107-2114, 1989.
17. Liu, J.C., Hsu, F.L., Tsai, J.C., Chan, P., Liu, J.Y.H., Thomas, G.N., Tomlinson, B., Lo, M.Y. and Lin, J.Y. Antihypertensive effects of tannins isolated from traditional Chinese herbs as non-specific inhibitors of angiotensin converting enzyme. Life Sci. 73: 1543-1555, 2003.
18. Maruyama, S., Mitachi, S., Tanaka, H., Tomizuka, N. and Suzuki, H. Studies on the active site antihypertensive activity of angiotensin I-converting enzyme inhibitor derived from casein. Agric. Biol. Chem. 51: 1581-1586, 1987.
19. Matoba, N., Doyama, N., Yamada, Y., Maruyama, N., Utsumi, S. and Yoshikawa, M. Design and production of genetically modified soybean protein with anti-hypertensive activity by incorporating potent analogue of ovokinin(2-7). FEBS Lett. 497: 50-54, 2001.
20. Matsas, R., Kenny, A.J. and Turner, A.J. The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11. Biochem. J. 223: 433-440, 1984.
21. Matsumura, N., Fujii, M., Takeda, Y. and Shimizu, T. Angiotensin I-converting enzyme inhibitory peptides derived from bonito bowels autolysate. Biosci. Biotech. Biochem. 57: 1743-1744, 1993.
22. Miyoshi, S., Kaneko, T., Yoshizawa, Y., Fukui, F., Tanaka, H. and Maruyama, S. Hypertensive activity of enzymatic α-zein hydrolysate. Agric. Biol. Chem. 5: 1407-1408, 1991.
23. Miyoshi, S., Ishikawa, H., Kaneko, T., Fukui, F., Tanaka, H. and Maruyama, S. Structures and activity of angiotensin-converting enzyme inhibitors in an α-zein hydrolysate. Agric. Biol. Chem. 55: 1313-1318, 1991.
24. Nakagomi, K., Yamada, R., Ebisu, H., Sadakane, Y., Akizawa, T. and Tanimura, T. Isolation of acein-2, a novel angiotensin I-converting enzyme inhibitory peptide derived from a tryptic hydrolysate of human plasma. FEBS Lett. 467: 235-238, 2000.
25. Nakamura, Y., Yamamoto, N., Sakai, K. and Takano, T. Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-converting enzyme. J. Dairy Sci. 78: 1253-1257, 1995.
26. Ni, L., Tao, G.J., Dai, J., Wang, Z. and Xu, S.Y. Separation, purification and identification of angiotensin converting enzyme inhibitory silk fibroin peptide. Se Pu 19: 222-225 (in Chinese), 2001.
27. Parker, F., Migliore-Samour, O., Floch, F., Zerial, A., Werner, G.H., Jolles, J., Casaretto, M., Zahn, H. and Jolles, P. Immunostimulating hexapeptide from human case in amino acid sequence, synthesis and biological properties. Eur. J. Biochem. 145: 677-682, 1984.
28. Pihlanto-Leppala, A., Koskinen, P., Piilola, K., Tupasela, T. and Korhonen, H. Angiotensin I-converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides. J. Dairy Res. 67: 53-64, 2000.
29. Ramabadran, K. and Bansinath, M. Pharmacology of β-casomorphins, opioid peptides derived from milk protein. Asia Pac. J. Pharmacol. 4: 45-49, 1989.
30. Scarborough, R.H., Rose, J.W., Hsu, M.H., Phillips, D.R., Fried, V.A., Campbell, A.M., Manniaai, L. and Charo, I.F. Barbourin AGpIIb-IIIa specific integrin antagonist from the venom of sistrurus M, Barbouri. J. Biol. Chem. 266: 9359-9360, 1991.
31. Sipola, M., Finckenberg, P., Santisteban, J., Korpela, R., Vapaatalo, H. and Nurminen, M.L. Long-term intake of milk peptides attenuates development of hypertension in spontaneously hypertensive rats. J. Physiol. Phatmacol. 52: 745-754, 2001.
32. Studdy, P.R., Lapworth, R. and Bird, R. Angiotension-converting enzyme and its clinical significance review. J. Clin. Pathol. 36: 938-947, 1983.
33. s2 -casein. FEBS Lett. 6: 369-374, 2002.
34. Yokoyama, K., Chiba, H. and Yoshikawa, M. Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito. Biosci. Biotechnol. Biochem. 56: 1541-1545, 1992.
35. Yoshii, H., Tachi, N., Ohba, R., Sakamura, O., Takeyama, H. and Itani, T. Antihypertensive effect of ACE inhibitory oligopeptides from chicken egg yolks. Comp. Biochem. Physiol. C: Toxicol. Pharmacol. 128: 27-33, 2001.
36. Zioudrou, C., Streaty, R.A. and Klee, W.A. Opioid peptides derived from food proteins. J. Biol. Chem. 254: 2446-2449, 1979.