Relationship between the adiponectin-leptin ratio and parameters of insulin resistance in subjects without hyperglycemia

Metabolism: Clinical and Experimental

Volumn 55, Issue 9, 2006, Pages 1248-1254

  Inoue, Minoru ^a   Yano, Masao ^b   Yamakado, Minoru ^b   Maehata, Eisuke ^c   Suzuki, Seiji ^d  

^a PL Tokyo Health Care Center   (Japan)

^b MITSUI MEMORIAL HOSPITAL   (Japan)

^c Prev Clin Laboratory Corporation   (Japan)

^d SHOWA UNIVERSITY FUJIGAOKA HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; GLUCOSE; HEPARIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LEPTIN; LIPOPROTEIN LIPASE; TRIACYLGLYCEROL;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; BODY MASS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DIET RESTRICTION; ENZYME BLOOD LEVEL; FEMALE; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; HUMAN; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INTERMETHOD COMPARISON; JAPAN; LIPID ANALYSIS; MAJOR CLINICAL STUDY; MALE; MODEL; MULTIPLE LINEAR REGRESSION ANALYSIS; PRIORITY JOURNAL; REGRESSION ANALYSIS; SEX DIFFERENCE; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPONECTIN; ADULT; BIOLOGICAL MARKERS; BLOOD GLUCOSE; FEMALE; HUMANS; HYPERGLYCEMIA; INSULIN; INSULIN RESISTANCE; JAPAN; LEPTIN; LIPIDS; MALE; MIDDLE AGED;

EID: 33747073136     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2006.05.010     Document Type: Article

References (54)

1. Matsuzawa Y., Funahashi T., and Nakamura T. Molecular mechanism of metabolic syndrome X: contribution of adipocyte-derived bioactive substance. Ann NY Acad Sci 892 (1999) 146-154
2. Scherer P.E., Williams S., Fogliano M., Baldini G., and Lodish H.F. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 270 (1995) 26746-26749
3. Hu E., Liang P., and Spigelman B.M. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 271 (1996) 10697-10703
4. Maeda K., Okubo K., Shimomura I., Funahashi T., Matsuzawa Y., and Matsubara K. cDNA cloning and expression of a novel adipose-specific collagen-like factor, apM1 (adipose most abundant gene transcript 1). Biochem Biophys Res Commun 221 (1996) 286-289
5. Nakano Y., Tobe T., Choi-Miura N.H., Mazda T., and Tomita M. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biol Chem 120 (1996) 803-812
6. Arita Y., Kihara S., Ouchi N., et al. Paradoxical decrease of an adipose-specific protein, adiponectin in obesity. Biochem Biophys Res Commun 257 (1999) 79-83
7. Hotta K., Funahashi T., Arita Y., et al. Plasma concentration of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 20 (2000) 1595-1599
8. Weyer c., Funahashi T., Tanaka, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 24 (2001) 1930-1935
9. Inoue M., Maehata E., Taniyama M., and Suzuki S. The role of adiponectin in patients with type 2 diabetes mellitus. J Anal Biosci 25 (2003) 145-152
10. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., and Friedman J.F. Positional cloning of mouse obese gene and its human homologue. Nature 372 (1994) 425-432
11. Considine R.V., Sinha M.K., Heiman M.L., et al. Serum immunoreactive-leptin concentration in normal-weight and obese humans. N Engl J Med 334 (1996) 292-295
12. Shimomura I., Hammer R.E., Ikemoto S., Brown M.S., and Goldstein J.L. Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature 401 (1999) 73-76
13. Chen Y., Ogawa H., Narita H., Ohtoh K., Yoshida T., and Yoshikawa Y. Ratio of leptin to adiponectin as an obesity index of cynomolgus monkeys (Macaca fascicularis). Exp Anim 52 (2003) 137-143
14. Satoh N., Naruse M., Usui T., et al. Leptin-to-adiponectin ratio as a potential atherogenic index in obese type 2 diabetic patients. Diabetes Care 27 (2004) 2488-2490
15. Kotani K., Sakane N., Saiga K., and Kurozawa Y. Leptin:adiponectin ratio as an atherosclerotic index in patients with type 2 diabetes: relationship of the index to carotid intima-media thickness. Diabetologia 1 (2005) 1-3
16. Inoue M., Maehata E., Yano M., Taniyama M., and Suzuki S. Correlation between the adiponectin/leptin ratio and parameters of insulin resistance in patients with type 2 diabetes. Metabolism 54 (2005) 281-286
17. Vigouroux C., Maachi M., Nguyen T.H., et al. Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy. AIDS 17 (2003) 1503-1511
18. DeFronzo R.A., Tobin J.D., and Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237 (1979) E214-E223
19. Matsuda M., and DeFronzo R.A. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetologia 28 (1999) 412-419
20. Shen S.W., Reaven G.M., and Farquhar L.W. Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes. J Clin Invest 49 (1970) 2151-2160
21. Turner R.C., Holman R.R., Matthews D., Hockaday T.D.R., and Peto J. Insulin deficiency and insulin resistance interaction in diabetes: estimation of their relative contribution by feedback analysis from basal plasma insulin and glucose concentrations. Metabolism 28 (1979) 1086-1096
22. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., and Turner R.C. Homeostasis model assessment: insulin resistance and B-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
23. Prato S.D., and Pozzilli P. FIRI fasting or false insulin resistance index?. Lancet 347 (1996) 132
24. Ono T., Shiga N., Tanabe Y., and Umemura S. The fasting-plasma glucose range in which insulin resistance measured by homeostasis model assessment correlates with euglycemic clamping. J Jpn Diabetes Soc 42 (1999) 1005-1011
25. Rossetti L., Giaccari A., and DeFrozo R.A. Glucose toxicity. Diabetes Care 13 (1990) 610-630
26. Marshall S., Bacote V., and Traxinhger R.R. Discovery of a metabolic pathway mediating glucose-induce desensitization of the glucose transport system. J Biol Chem 266 (1991) 4706-4712
27. Rossetti L., Hawkins M., Chen W., Gindi J., and Barzililai N. In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious rats. J Clin Invest 96 (1995) 132-140
28. Mclain D.A., and Crook E.D. Hexosamines and insulin resistance. Diabetes 45 (1996) 1003-1009
29. Crook E.D., Zhou J., Daniels M., Neidigh J.L., and McClain D.A. Regulation of glycogen synthase by glucose, glucosamine, and glutamine: fructose-6-phosphate aminotransferase. Diabetes 44 (1995) 314-320
30. Lee T.S., Saltaman K.A., Ohashi H., and King G.L. Activation of protein kinase C by glucose. Proc Natl Acad Sci U S A 86 (1989) 5141-5145
31. Berti L., Mosthaf L., Kroder G., et al. Glucose-induced translocation of protein kinase C isoforms in rat-l fibroblasts is paralleled by inhibition of the insulin receptor tyrosine kinase. J Biol Chem 269 (1994) 3381-3386
32. Kaplan N.M. The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. Arch Intern Med 49 (1989) 1514-1520
33. DeFronzo R.A. Insulin resistance: multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerosis. Neth J Med 50 (1997) 191-197
34. Moller D.E., and Kaufman K.D. Metabolic syndrome: a clinical and molecular perspective. Annu Rev Med 56 (2005) 45-62
35. Grundy S.M. Hypertriglyceridemia, insulin resistance, and the metabolic syndrome. Am J Cardiol 83 (1999) 25F-29F
36. Arita Y., Kihara S., Ouchi N., Takahashi M., Maeda K., Miyagawa J., et al. Paradoxical decrease of an adipose-specific protein, adiponectin in obesity. Biochem Biophys Res Comm 257 (1999) 79-83
37. Kobayashi J., Hashimoto H., Fukamachi I., Tashiro J., Shirai K., Saito Y., et al. Lipoprotein lipase mass and activity in severe hypertriglyceridemia. Clin Chim Acta 216 (1993) 113-123
38. Jebb S.A., Cole T.J., Doman D., Murgatroyd P.R., and Prentice A.M. Evaluation of the novel Tanita body-fat analyzer to measure body composition by comparison with a four-compartment model. Br J Nutr 83 (2000) 115-122
39. Folson A.R., Prineas R.J., Kaye S.A., and Munger R.G. Incidence of hypertension and stroke in relation to body fat distribution and other risk factors in older women. Stroke 21 (1990) 701-706
40. Cassano P.A., Segal M.R., Vokonas P.S., and Weiss S.T. Body fat distribution, blood pressure, and hypertension. A prospective cohort study of men in the normative aging study. Ann Epidemiol 1 (1990) 33-48
41. Kissebah A.H., and Peiris A.N. Biology of regional body fat distribution: relationship to non-insulin dependent diabetes mellitus. Diabetes Metab Rev 5 (1989) 83-109
42. Chan J.M., Rimm E.B., Colditz G.A., Stamfer M.J., and Willtt W.C. Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men. Diabetes Care 17 (1994) 961-969
43. Folsom A.R., Stevens J., Schereiner P.J., and McGovern P.G. Body mass index, waist-hip ratio, and coronary heart disease incidence in African Americans and whites. Am J Epidemiol 148 (1998) 1187-1194
44. Megnein J.L., Denarie N., Cocaul M., Simon A., and Levenson J. Predictive value of waist-to-hip ratio on cardiovascular risk events. Int J Obes Relat Metab Disord 23 (1999) 90-97
45. Reaven G.M. Pathophysiology of insulin resistance in human disease. Physiol Rev 75 (1995) 473-486
46. Ferrara C.M., and Goldberg A.P. Limited value of the homeostasis model assessment to predict insulin resistance in older men with impaired glucose tolerance. Diabetes Care 24 (2001) 245-249
47. Katsuki A., Sumida Y., Urakawa H., et al. Neither homeostasis model assessment nor quantitative insulin sensitivity check index can predict insulin resistance in elderly patients with poorly controlled type 2 diabetes mellitus. J Clin Endocrinol Metab 87 (2002) 5332-5335
48. Ahima R.S., and Flier J.S. Adipose tissue as an endocrine organ. Trends Endocrinol Metab 11 (2000) 327-331
49. Berg A.H., Combs T.P., and Scherer P.E. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 13 (2002) 84-89
50. Fruebis J., Tsao T.S., Javorschi S., Ebbets-Reed D., Erickson M.R., Yen F.T., et al. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Nalt Acad Sci U S A 98 (2001) 2005-2010
51. Baskin D.G., Blevins J.E., and Schwatz M.W. How the brain regulates food intake and body weight: the role of leptin. J Pediatr Endocrinol Metab 14 (2001) 1417-1419
52. Brabant G., Nave H., Mayr B., Behrend M., Harmelen V., and Arner P. Secretion of free and protein-bound leptin from subcutaneous adipose tissue of lean obese women. J Clin Endocrinol Metab 87 (2002) 3966-3970
53. Yang W.S., Lee W.J., Funahashi T., Tanaka S., Matsuzawa Y., Chao C.L., et al. Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J Clin Endocrinol Metab 86 (2001) 3815-3819
54. Yamauchi T., Kamon J., Waki H., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7 (2001) 941-946