Animal models of cavitation in pulmonary tuberculosis

Tuberculosis

Volumn 86, Issue 5, 2006, Pages 337-348

  Helke, Kris L ^a   Mankowski, Joseph L ^a   Manabe, Yukari C ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Animal models; Cavitation; Guinea pig; Monkey; Rabbit; Review; Tuberculosis

Indexed keywords

BACTERIAL PROTEIN; BCG VACCINE; GAMMA INTERFERON; INACTIVATED VACCINE; INTERLEUKIN 4; LIPOPROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; BACTERIAL TRANSMISSION; BACTERIAL VIRULENCE; CATTLE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; COMPARATIVE STUDY; DISEASE TRANSMISSION; GUINEA PIG; HOST PATHOGEN INTERACTION; HUMAN; IMMUNE DEFICIENCY; IMMUNE SYSTEM; IMMUNIZATION; IMMUNOCOMPETENCE; INFECTION SENSITIVITY; LUNG CAVITATION; LUNG GRANULOMA; LUNG TUBERCULOSIS; MONKEY; MYCOBACTERIUM AVIUM; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENESIS; PRIMATE; PRIORITY JOURNAL; PROVOCATION TEST; RABBIT; REVIEW; TH1 CELL; TH2 CELL; TISSUE NECROSIS; TUBERCULIN TEST;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CATTLE; DISEASE MODELS, ANIMAL; DOGS; ELEPHANTS; GOATS; GUINEA PIGS; HAPLORHINI; HORSES; HUMANS; MICE; MYCOBACTERIUM TUBERCULOSIS; RABBITS; SHEEP; SWINE; TUBERCULOSIS, PULMONARY;

EID: 33747068829     PISSN: 14729792     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tube.2005.09.001     Document Type: Review

References (99)

1. Rich A.R. The pathogenesis of tuberculosis (1991), Charles C. Thomas, Springfield, Illinois
2. Dannenberg Jr. A.M., and Sugimoto M. Liquefaction of caseous foci in tuberculosis. Am Rev Respir Dis 113 (1976) 257-259
3. Converse P.J., et al. Pulmonary bovine-type tuberculosis in rabbits: bacillary virulence, inhaled dose effects, tuberculin sensitivity, and Mycobacterium vaccae immunotherapy. Clin Diagn Lab Immunol 5 (1998) 871-881
4. Canetti G. The tubercle bacillus (1955), Springer Publishing company, Inc., New York
5. Blanchard J.S. Molecular mechanisms of drug resistance in Mycobacterium tuberculosis. Annu Rev Biochem 65 (1996) 215-239
6. Grosset J. Mycobacterium tuberculosis in the extracellular compartment: an underestimated adversary. Antimicrob Agents Chemother 47 (2003) 833-836
7. Rouillon A., Perdrizet S., and Parrot R. Transmission of tubercle bacilli: the effects of chemotherapy. Tubercle 57 (1976) 275-299
8. Rose Jr. C.E., Zerbe G.O., Lantz S.O., and Bailey W.C. Establishing priority during investigation of tuberculosis contacts. Am Rev Respir Dis 119 (1979) 603-609
9. Capewell S., and Leitch A.G. The value of contact procedures for tuberculosis in Edinburgh. Br J Dis Chest 78 (1984) 317-329
10. Mitchison D.A. Assessment of new sterilizing drugs for treating pulmonary tuberculosis by culture at 2 months. Am Rev Respir Dis 147 (1993) 1062-1063
11. Rieder H.L. Sputum smear conversion during directly observed treatment for tuberculosis. Tuberc Lung Dis 77 (1996) 124-129
12. Hiyama J., Marukawa M., Shiota Y., Ono T., and Mashiba H. Factors influencing response to treatment of pulmonary tuberculosis. Acta Med Okayama 54 (2000) 139-145
13. Lienhardt C., et al. Factors determining the outcome of treatment of adult smear-positive tuberculosis cases in The Gambia. Int J Tuberc Lung Dis 2 (1998) 712-718
14. Dominguez-Castellano A., et al. Factors associated with time to sputum smear conversion in active pulmonary tuberculosis. Int J Tuberc Lung Dis 7 (2003) 432-438
15. Singla R., et al. Factors predicting persistent sputum smear positivity among pulmonary tuberculosis patients 2 months after treatment. Int J Tuberc Lung Dis 7 (2003) 58-64
16. Benator D., et al. Rifapentine and isoniazid once a week versus rifampicin and isoniazid twice a week for treatment of drug-susceptible pulmonary tuberculosis in HIV-negative patients: a randomised clinical trial. Lancet 360 (2002) 528-534
17. Salaniponi F.M., Christensen J.J., Gausi F., Kwanjana J.J., and Harries A.D. Sputum smear status at two months and subsequent treatment outcome in new patients with smear-positive pulmonary tuberculosis. Int J Tuberc Lung Dis 3 (1999) 1047-1048
18. Brindle R.J., et al. Quantitative bacillary response to treatment in HIV-associated pulmonary tuberculosis. Am Rev Respir Dis 147 (1993) 958-961
19. Mazzarella G., et al. T lymphocyte phenotypic profile in lung segments affected by cavitary and non-cavitary tuberculosis. Clin Exp Immunol 132 (2003) 283-288
20. Condos R., Rom W.N., Liu Y.M., and Schluger N.W. Local immune responses correlate with presentation and outcome in tuberculosis. Am J Respir Crit Care Med 157 (1998) 729-735
21. Ozaki T., et al. Differential cell analysis in bronchoalveolar lavage fluid from pulmonary lesions of patients with tuberculosis. Chest 102 (1992) 54-59
22. Ashitani J., et al. Elevated levels of alpha-defensins in plasma and BAL fluid of patients with active pulmonary tuberculosis. Chest 121 (2002) 519-526
23. van Crevel R., et al. Increased production of interleukin 4 by CD4+ and CD8+ T cells from patients with tuberculosis is related to the presence of pulmonary cavities. J Infect Dis 181 (2000) 1194-1197
24. Somoskovi A., et al. Different cytokine patterns correlate with the extension of disease in pulmonary tuberculosis. Eur Cytokine Network 10 (1999) 135-142
25. Tsao T.C., et al. Imbalances between tumor necrosis factor-alpha and its soluble receptor forms, and interleukin-1beta and interleukin-1 receptor antagonist in BAL fluid of cavitary pulmonary tuberculosis. Chest 117 (2000) 103-109
26. Roach D.R., et al. TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection. J Immunol 168 (2002) 4620-4627
27. Mohan V.P., et al. Effects of tumor necrosis factor alpha on host immune response in chronic persistent tuberculosis: possible role for limiting pathology. Infect Immun 69 (2001) 1847-1855
28. Bean A.G., et al. Structural deficiencies in granuloma formation in TNF gene-targeted mice underlie the heightened susceptibility to aerosol Mycobacterium tuberculosis infection, which is not compensated for by lymphotoxin. J Immunol 162 (1999) 3504-3511
29. Zganiacz A., et al. TNF-alpha is a critical negative regulator of type 1 immune activation during intracellular bacterial infection. J Clin Invest 113 (2004) 401-413
30. Orme I., and Collins F.M. In: Bloom B.R. (Ed). Tuberculosis: pathogenesis, protection, and control (1994), American Society for Microbiology, Washington, DC 113-134
31. Flynn J.L., Cooper A.M., and Bishai W.R. In: Cole S.T., Eisenach K.D., McMurray D.N., and Jacobs Jr. W.R. (Eds). Tuberculosis and the tubercle bacillus (2005), American Society for Microbiology, Washington, DC 547-560
32. Dunn P.L., and North R.J. Virulence ranking of some Mycobacterium tuberculosis and Mycobacterium bovis strains according to their ability to multiply in the lungs, induce lung pathology, and cause mortality in mice. Infect Immun 63 (1995) 3428-3437
33. Flynn J.L., and Chan J. Immunology of tuberculosis. Annu Rev Immunol 19 (2001) 93-129
34. Ehlers S., Kutsch S., Ehlers E.M., Benini J., and Pfeffer K. Lethal granuloma disintegration in mycobacteria-infected TNFRp55-/- mice is dependent on T cells and IL-12. J Immunol 165 (2000) 483-492
35. Ehlers S., et al. Alphabeta T cell receptor-positive cells and interferon-gamma, but not inducible nitric oxide synthase, are critical for granuloma necrosis in a mouse model of mycobacteria-induced pulmonary immunopathology. J Exp Med 194 (2001) 1847-1859
36. Benini J., Ehlers E.M., and Ehlers S. Different types of pulmonary granuloma necrosis in immunocompetent vs. TNFRp55-gene-deficient mice aerogenically infected with highly virulent Mycobacterium avium. J Pathol 189 (1999) 127-137
37. Florido M., Cooper A.M., and Appelberg R. Immunological basis of the development of necrotic lesions following Mycobacterium avium infection. Immunology 106 (2002) 590-601
38. Wangoo A., et al. Contribution of Th1 and Th2 cells to protection and pathology in experimental models of granulomatous lung disease. J Immunol 166 (2001) 3432-3439
39. Smith D.W., McMurray D.N., Wiegeshaus E.H., Grover A.A., and Harding G.E. Host-parasite relationships in experimental airborne tuberculosis. IV. Early events in the course of infection in vaccinated and nonvaccinated guinea pigs. Am Rev Respir Dis 102 (1970) 937-949
40. Wiegeshaus E.H., McMurray D.N., Grover A.A., Harding G.E., and Smith D.W. Host-parasite relationships in experimental airborne tuberculosis. 3. Relevance of microbial enumeration to acquired resistance in guinea pigs. Am Rev Respir Dis 102 (1970) 422-429
41. Alsaadi A.I., and Smith D.W. The fate of virulent and attenuated Mycobacteria in guinea pigs infected by the respiratory route. Am Rev Respir Dis 107 (1973) 1041-1046
42. Balasubramanian V., Wiegeshaus E.H., and Smith D.W. Growth characteristics of recent sputum isolates of Mycobacterium tuberculosis in guinea pigs infected by the respiratory route. Infect Immun 60 (1992) 4762-4767
43. Balasubramanian V., Wiegeshaus E.H., and Smith D.W. Mycobacterial infection in guinea pigs. Immunobiology 191 (1994) 395-401
44. Francis J. Tuberculosis in animals and man. A study in comparative pathology (1958), Cassell and Company, Ltd., London
45. Fok J.S., Ho R.S., Arora P.K., Harding G.E., and Smith D.W. Host-parasite relationships in experimental airborne tuberculosis. V. Lack of hematogenous dissemination of Mycobacterium tuberculosis to the lungs in animals vaccinated with Bacille Calmette-Guerin. J Infect Dis 133 (1976) 137-144
46. Ho R.S., Fok J.S., Harding G.E., and Smith D.W. Host-parasite relationships in experimental airborne tuberculosis. VII. Fate of Mycobacterium tuberculosis in primary lung lesions and in primary lesion-free lung tissue infected as a result of bacillemia. J Infect Dis 138 (1978) 237-241
47. Turner O.C., Basaraba R.J., and Orme I.M. Immunopathogenesis of pulmonary granulomas in the guinea pig after infection with Mycobacterium tuberculosis. Infect Immun 71 (2003) 864-871
48. Lurie M. Experimental epidemiology of tuberculosis: the effect of eliminating exposure of enteric infection on the incidence and course of tuberculosis acquired by normal guinea pigs confined with tuberculous cage mates. J Exp Med 51 (1930) 753-768
49. Lurie M. Experimental epidemiology of tuberculosis: air-borne contagion of tuberculosis in an animal room. J Exp Med 51 (1930) 743-751
50. Smith D.W., and Harding G.E. Animal model of human disease. Pulmonary tuberculosis. Animal model: Experimental airborne tuberculosis in the guinea pig. Am J Pathol 89 (1977) 273-276
51. Yamamura Y. The Pathogenesis of Tuberculous Cavities. Adv Tuberc Res 9 (1958) 13-37
52. Good R.C. Biology of the mycobacterioses. Simian tuberculosis: immunologic aspects. Ann N Y Acad Sci 154 (1968) 200-213
53. Barclay W.R., et al. Protection of monkeys against airborne tuberculosis by aerosol vaccination with bacillus Calmette-Guerin. Am Rev Respir Dis 107 (1973) 351-358
54. Chaparas S.D., Good R.C., and Janicki B.W. Tuberculin-induced lymphocyte transformation and skin reactivity in monkeys vaccinated or not vaccinated with Bacille Calmette-Guerin, then challenged with virulent Mycobacterium tuberculosis. Am Rev Respir Dis 112 (1975) 43-47
55. Janicki B.W., Good R.C., Minden P., Affronti L.F., and Hymes W.F. Immune responses in rhesus monkeys after bacillus Calmette-Guerin vaccination and aerosol challenge with Mycobacterium tuberculosis. Am Rev Respir Dis 107 (1973) 359-366
56. Ribi E., et al. Efficacy of mycobacterial cell walls as a vaccine against airborne tuberculosis in the Rhesus monkey. J Infect Dis 123 (1971) 527-538
57. Schmidt L.H., Hoffman R., and Hughes H.B. The toxicity of isoniazid for the rhesus monkey. Am Rev Tuberc 67 (1953) 798-807
58. Schmidt L.H. Studies on the antituberculous activity of ethambutol in monkeys. Ann N Y Acad Sci 135 (1966) 747-758
59. Wolf R.H., Gibson S.V., Watson E.A., and Baskin G.B. Multidrug chemotherapy of tuberculosis in rhesus monkeys. Lab Anim Sci 38 (1988) 25-33
60. Langermans J.A., et al. Divergent effect of bacillus Calmette-Guerin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: implications for primate models in tuberculosis vaccine research. Proc Natl Acad Sci USA 98 (2001) 11497-11502
61. Corcoran K.D., and Jaax G.P. An attempt to predict anergy in tuberculosis suspect cynomolgus monkeys. Lab Anim Sci 41 (1991) 57-62
62. Schroeder C.R. Acquired tuberculosis in the primate in laboratories and zoological collections. Am J Public Health 28 (1938) 469-475
63. Zumpe D., Silberman M.S., and Michael R.P. Unusual outbreak of tuberculosis due to Mycobacterium bovis in a closed colony of rhesus monkeys (Macaca mulatta). Lab Anim Sci 30 (1980) 237-240
64. Capuano III S.V., et al. Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infection. Infect Immun 71 (2003) 5831-5844
65. Walsh G.P., et al. The Philippine cynomolgus monkey (Macaca fasicularis) provides a new nonhuman primate model of tuberculosis that resembles human disease. Nat Med 2 (1996) 430-436
66. Schmidt L.H. Some observations on the utility of simian tuberculosis in defining the therapeutic potentialities of isoniazid. Annu. Rev. Tuberc. Pulm. Dis. 74 (1955) 138-153
67. Francis J. Natural and experimental tuberculosis in monkeys. J. Comp. Pathol. 66 (1956) 123-135
68. Lurie M.B. The fate of human and bovine tubercle bacilli in various organs of the rabbit. J Exp Med 48 (1928) 155-182
69. Manabe Y.C., et al. Different strains of Mycobacterium tuberculosis cause various spectrums of disease in the rabbit model of tuberculosis. Infect Immun 71 (2003) 6004-6011
70. Heppleston A.G. Quantitative air-borne tuberculosis in the rabbit. J Exp Med 89 (1949) 597-610
71. Lurie M.B. Resistance to tuberculosis (1964), Harvard University Press, Cambridge
72. Lurie M.B., Abramson S., and Heppleston A.G. On the response of genetically resistant and susceptible rabbits to the quantitative inhalation of human-type tubercle bacilli and the nature of resistance to tuberculosis. J Exp Med 95 (1952) 119-134
73. Converse P.J., et al. Cavitary tuberculosis produced in rabbits by aerosolized virulent tubercle bacilli. Infect Immun 64 (1996) 4776-4787
74. Takeda K, Shinpo K. On the meaning of the allergic tissue reaction as regards the development of pulmonary tuberculosis. Kekkaku 1942;20:208-21, 275-90, 472-89.
75. Dannenberg Jr. A.M., and Collins F.M. Progressive pulmonary tuberculosis is not due to increasing numbers of viable bacilli in rabbits, mice and guinea pigs, but is due to a continuous host response to mycobacterial products. Tuberculosis 81 (2001) 229-242
76. Wells W., and Lurie M.B. Experimental airborne disease: quantitative natureal respiratory contagion of tuberculosis. Am J Hyg 34 (1941) 21
77. Ratcliffe H.L., and Wells W.F. Tuberculosis of rabbits induced by droplet nuclei infection. J Exp Med 87 (1948) 575-584
78. Yamamura Y., et al. Studies on the experimental tuberculous cavity. Med. J. Osaka Univ. 5 (1954) 187-197
79. Yamamura Y., Ogawa Y., and Yamagata H. Prevention of tuberculous cavity formation by immunosuppressive drugs. Am Rev Respir Dis 98 (1968) 720-723
80. Maeda H., Yamamura Y., Ogawa Y., and Maeda J. Mycobacterial antigens relating to experimental pulmonary cavity formation. Am Rev Respir Dis 115 (1977) 617-623
81. Yamamura Y., Maeda H., Ogawa Y., and Hashimoto T. Experimental pulmonary cavity formation by mycobacterial components and synthetic adjuvants. Microbiol Immunol 30 (1986) 1175-1187
82. Yamamura Y., Ogawa Y., Maeda H., and Yamamura Y. Prevention of tuberculous cavity formation by desensitization with tuberculin-active peptide. Am Rev Respir Dis 109 (1974) 594-601
83. Alfredsen S., and Saxegaard F. An outbreak of tuberculosis in pigs and cattle caused by Mycobacterium africanum. Vet Rec 131 (1992) 51-53
84. Corner L.A., Barrett R.H., Lepper A.W., Lewis V., and Pearson C.W. A survey of mycobacteriosis of feral pigs in the Northern Territory. Austral Vet J 57 (1981) 537-542
85. Bolin C.A., et al. Infection of swine with Mycobacterium bovis as a model of human tuberculosis. J Infect Dis 176 (1997) 1559-1566
86. Muscoplat C.C., Thoen C.O., Chen A.W., Rakich P.M., and Johnson D.W. Development of specific lymphocyte immunostimulation and tuberculin skin reactivity in swine infected with Mycobacterium bovis and Mycobacterium avium. Am J Vet Res 36 (1975) 1167-1171
87. Ray J.A., Mallmann V.H., Mallmann W.L., and Morrill C.C. Pathologic and bacteriologic features and hypersensitivity of pigs given Mycobacterium bovis, Mycobacterium avium, or group 3 Mycobacteria. Am J Vet Res 33 (1972) 1333-1345
88. Hewinson R.G., Vordermeier H.M., and Buddle B.M. Use of the bovine model of tuberculosis for the development of improved vaccines and diagnostics. Tuberculosis (Edinburgh) 83 (2003) 119-130
89. Vordermeier H.M., et al. Correlation of ESAT-6-specific gamma interferon production with pathology in cattle following Mycobacterium bovis BCG vaccination against experimental bovine tuberculosis. Infect Immun 70 (2002) 3026-3032
90. Whelan A.O., et al. Modulation of the bovine delayed-type hypersensitivity responses to defined mycobacterial antigens by a synthetic bacterial lipopeptide. Infect Immun 71 (2003) 6420-6425
91. Smith D.W., Wiegeshaus E., Navalkar R., and Grover A.A. Host-parasite relationships in experimental airborne tuberculosis. I. Preliminary studies in BCG-vaccinated and nonvaccinated animals. J Bacteriol 91 (1965) 718-724
92. McMurray D.N., Bartow R.A., and Mintzer C.L. Impact of protein malnutrition on exogenous reinfection with Mycobacterium tuberculosis. Infect Immun 57 (1989) 1746-1749
93. Yoder M., Lamichhane G., and Bishai W.R. Cavitary pulmonary tuberculosis: the Holy Grail of disease transmission. Curr Sci 86 (2004) 74-81
94. von Reyn C.F., and Vuola J.M. New vaccines for the prevention of tuberculosis. Clin Infect Dis 35 (2002) 465-474
95. Kesavan A.K., et al. Effects of dexamethasone and transient malnutrition on rabbits infected with aerosolized Mycobacterium tuberculosis CDC1551. Infect Immun 73 (2005) 7056-7060
96. Iseman M. In: Iseman M. (Ed). A clinician's guide to tuberculosis (2000), Lipincott, Williams & Wilkins, Philadelphia
97. McMurray D.N., Dai G., and Phalen S. Mechanisms of vaccine-induced resistance in a guinea pig model of pulmonary tuberculosis. Tuberc Lung Dis 79 (1999) 261-266
98. Bartow R.A., and McMurray D.N. Vaccination with Mycobacterium bovis BCG affects the distribution of Fc receptor-bearing T lymphocytes in experimental pulmonary tuberculosis. Infect Immun 57 (1989) 1374-1379
99. Nardell E., McInnis B., Thomas B., and Weidhaas S. Exogenous reinfection with tuberculosis in a shelter for the homeless. N Engl J Med 315 (1986) 1570-1575