Selective nuclear factor κ-B inhibitors, pyrolidium dithiocarbamate and sulfasalazine, prevent the nephrotoxicity induced by gentamicin

BJU International

Volumn 98, Issue 3, 2006, Pages 680-686

  Tugcu, Volkan ^a,e   Ozbek, Emin ^b   Tasci, Ali I ^a   Kemahli, Eray ^a   Somay, Adnan ^b   Bas, Muzaffer ^a   Karaca, Cetin ^c   Altug, Tuncay ^c   Çekmen, Mustafa B ^d   Özdogan, Haci K ^d  

^a BAKIRKOY DR SADI KONUK TRAINING AND RESEARCH HOSPITAL   (Turkey)

^b Vakif Gureba Teaching and Research Hospital   (Turkey)

^c ISTANBUL UNIVERSITY   (Turkey)

^d KOCAELI UNIVERSITY   (Turkey)

^e NONE   (Turkey)

Author keywords

Gentamicin; iNOS; Nephrotoxicity; Pyrolidium dithiocarbamate; Selective nuclear factor B; Sulfasalazine

Indexed keywords

CREATININE; DITHIOCARBAMIC ACID DERIVATIVE; EOSIN; FORMALDEHYDE; GAMMA GLUTAMYLTRANSFERASE; GENTAMICIN; GLUTATHIONE; HEMATOXYLIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; MONOCLONAL ANTIBODY; NITRIC OXIDE; POTASSIUM ION; PYROLIDIUM DITHIOCARBAMATE; SALAZOSULFAPYRIDINE; SODIUM ION; SYNAPTOTAGMIN; UNCLASSIFIED DRUG; UREA; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFECT; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY CORTEX; KIDNEY MEDULLA; KIDNEY TUBULE NECROSIS; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; UREA BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL;

ANIMALS; GENTAMICINS; I-KAPPA B PROTEINS; IMMUNOHISTOCHEMISTRY; KIDNEY DISEASES; MALE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; SULFASALAZINE; THIOCARBAMATES;

EID: 33747029315     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2006.06321.x     Document Type: Article

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