Pathophysiological factors underlying heatstroke

Medical Hypotheses

Volumn 67, Issue 3, 2006, Pages 609-617

  Yan, You E ^a,b   Zhao, Yong Qi ^a,b   Wang, Hui ^a,b   Fan, Ming ^a,b  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIOXIDANT; FREE RADICAL; HEAT SHOCK PROTEIN; PEROXY RADICAL; PROTEIN INHIBITOR; SUPEROXIDE;

AGING; ARTICLE; BRAIN ISCHEMIA; CELL DAMAGE; CLINICAL PROTOCOL; CYTOPATHOGENIC EFFECT; DEHYDRATION; GENETIC POLYMORPHISM; HEAT SHOCK RESPONSE; HEAT STROKE; HEAT TOLERANCE; HUMAN; HYPERPYREXIA; HYPERTHERMIA; HYPOTENSION; INFLAMMATION; INSOMNIA; INTRACRANIAL HYPERTENSION; LIPID PEROXIDATION; METABOLIC DISORDER; MULTIPLE ORGAN FAILURE; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION;

ANIMALS; HEAT STROKE; HUMANS; MODELS, BIOLOGICAL;

EID: 33746997979     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2005.12.048     Document Type: Article

References (55)

1. Lin M.T., and Chang C.P. The neuropharmacological basis of heat intolerance and its treatment. J Thermal Biol 29 (2004) 463-469
2. Hammami M.M., Bouchama A., al-sedairy S., Shail E., AlOhaly Y., and Mohamed G. Concentrations of soluble tumor necrosis factor and interleukin-6 receptors in heatshock and heatstress. Crit Care Med 25 (1997) 1314-1319
3. Bouchama A., and Knochel J.P. Heatstroke. N Engl J Med 346 (2002) 1978-1988
4. Epstein Y., Hadad E., and Shapiro Y. Pathological factors underlying hyperthermia. J Thermal Bio 29 (2004) 487-494
5. Knochel J.P., and Reed G. Disorders of heat regulation. In: Narins R.G. (Ed). Maxwell and Kleeman's clinical disorders of fluid and electrolyte metabolism. 5th ed. (1994), McGraw-Hill, New York 1549-1590
6. al Mashhadani S.A., Gader A.G., al Harthi S.S., Kangav D., Shaheen F.A., and Bogus F. The coagulopathy of heatstroke: alterations in coagulation and fibrinolysis in heatstroke patients during the pilgrimage (Haj) to Makkah. Blood Coagul Fibrinolysis 5 (1994) 731-736
7. Epstein Y. Exertional heatstroke: lessons we tend to forget. Am J Sports Med 2 (2000) 143-152
8. Wang Z.Z., Wang C.L., Wu T.C., Pan H.N., Wang S.K., and Jiang J.D. Autoantibody response to heat shock protein 70 in patients with heatstroke. Am J Med 111 (2001) 654-657
9. Zhang H.J., Drake V.J., Morrison J.P., Oberley L.W., and Kregel K.C. Differential expression of stress-related genes with aging and hyperthermia. J Appl Physiol 92 (2002) 1762-1769
10. Lin M.T. Pathogenesis of an experimental heatstroke model. Clin Exp Pharmacol Physiol 26 (1999) 826-827
11. Liu C.C., Ke D., Chen Z.C., and Lin M.T. Hydroxyethyl starch produces attenuation of circulatory shock and cerebral ischemia during heatstroke. Shock 22 (2004) 288-294
12. Wang N.L., Liou Y.L., Lin M.T., Lin C.L., and Chang C.K. Chinese herbal medicine, Shengmai San, is effective for improving circulatory shock and oxidative damage in the brain during heatstroke. J Pharmacol Sci 97 (2005) 253-265
13. Wang N.L., Chang C.K., Liou Y.L., Lin C.L., and Lin M.T. Shengmai san, a chinese herbal medicine protects against rat heatstroke by reducing inflammatory cytokines and nitric oxide formation. J Pharmacol Sci 98 (2005) 1-7
14. Huang Y.P., Lin M.T., Chen J.S., and Wu P.Y. Naltrexone protects against hypotension, hyperthermia, and beta-endorphin overproduction during heatstroke in the rat. J Pharmacol Sci 97 (2005) 519-524
15. Chang C.P., Lee C.C., Chen S.H., and Lin M.T. Aminoguanidine protects against intracranial hypertension and cerebral ischemic injury in experimental heatstroke. J Pharmacol Sci 95 (2004) 56-64
16. Chen S.H., Chang F.M., Tsai Y.C., Huang K.F., and Lin M.T. Resuscitation from experimental heatstroke by transplantation of human umbilical cord blood cells. Crit Care Med 33 (2005) 1377-1383
17. Tsai H.M., Gao C.J., Li W.X., Lin M.T., and Niu K.C. Resuscitation from experimental heatstroke by hyperbaric oxygen therapy. Crit Care Med 33 (2005) 813-818
18. Wen Y.S., Huang M.S., Lin M.T., and Lee C.H. Hypothermic retrograde jugular vein flush in heatstroke rats provides brain protection by maintaining cerebral blood flow but not by hemodilution. Crit Care Med 32 (2004) 1391-1395
19. Sonna L.A., Fujita J., Gaffin S.L., and Lilly C.M. Effects of heat and cold stress on mammalian gene expression. J Appl Physiol 92 (2002) 1725-1742
20. Sonna L.A., Gaffin S.L., Pratt R.E., Cullivan1 M., Angel1 K.C., and Lilly C.M. Effect of acute heat shock on gene expression by human peripheral blood mononuclear cells. J Appl Physiol 92 (2002) 1762-1769
21. Kregel K.C. Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance. J Appl Physiol 92 (2002) 2177-2186
22. Urano M., Kuroda M., and Nishimura Y. For the clinical application of themochemotherapy given at mild temperatures. Int J Hyperthermia 15 (1999) 79-107
23. Dewey W.C. Arrhenius relationships from the molecule and cell to the clinic. Int J Hyperthermia 10 (1994) 457-483
24. Dewhirst M.W., Prosnitz L., Thrall D., Prescott D., Clegg S., MacFall J., et al. Hyperthermic treatment of malignant disease: current status and a view toward the future. Semin Oncol 24 (1997) 616-625
25. Hildebrandt B., Wust P., Ahlers O., Dieing A., Sreenivasa G., Kerner T., et al. The cellular and molecular basis of hyperthermia. Crit Rev Oncol Hemat 43 (2002) 33-56
26. Borrelli M.J., Garlini W.G., Ransom B.R., and Dewey W.C. A direct correlation between hyperthermia induced membrane blebbing and survival in synchronous G1 CHO cells. J Cell Physiol 126 (1986) 181-190
27. Zhao Y.Q., Liu S.H., Zhao Y.L., Wu Y., Ge X.M., Liao J., et al. Membrane damage in rat striatum neurons by heat treatment. Chinese J Cell Biol 26 (2004) 72-75
28. Gabay C., and Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 340 (1999) 448-454
29. Cannon J.G., and Kluger M.J. Endogenous pyrogen activity in human plasma after exercise. Science 220 (1983) 617-619
30. Hietala J., Nurmi T., Uhari M., Pakarinen A., and Kouvalainen K. Acute phase proteins, humoral and cell mediated immunity in environmentally-induced hyperthermia in man. Eur J Appl Physiol Occup Physiol 49 (1982) 271-276
31. Hammami M.M., Bouchama A., Shail E., and al-Sedairy S. Elevated serum level of soluble interleukin-2 receptor in heatstroke. Intens Care Med 24 (1998) 988
32. Sonna L.A., Wenger C.B., Flinn S., Sheldon H.K., Sawka M.N., and Lilly C.M. Exertional heat injury and gene expression changes: a DNA microarray analysis study. J Appl Physiol 96 (2004) 1943-1953
33. Bouchama A., Roberts G., Al Mohanna F., El-Sayed R., Lach B., Chollet-Martin S., et al. Inflammatory, hemostatic, and clinical changes in a baboon experimental model for heatstroke. J Appl Physiol 98 (2005) 697-705
34. Bouchama A., Mohanna F.A., El-Sayed R., Eldali A., Saussereau E., Chollet-Martin S., et al. Experimental heatstroke in baboon: analysis of the systemic inflammatory response. Shock 24 (2005) 332-335
35. Moseley P.L. Heatstroke proteins and heat adaptation of the whole organism. J Appl Physiol 83 (1997) 1413-1417
36. Pals K.L., Chang R.T., Ryan A.J., and Gisolfi C.V. Effect of running intensity on intestinal permeability. J Appl Physiol 82 (1997) 571-576
37. Sakurada S., and Hales J.R. A role for gastrointestinal endotoxins in enhancement of heat tolerance by physical fitness. J Appl Physiol 84 (1998) 207-214
38. Liu C.C., Chien C.H., and Lin M.T. Glucocorticoids reduce interleukin-1 concentration and result in neuroprotective effects in rat heatstroke. J Physiol 527 (2000) 333-343
39. Gathiram P., Wells M.T., Brock-Utne J.G., and Gaffin S.L. Antilipopolysaccharide improves survival in primates subjected to heatstroke. Circ Shock 23 (1987) 157-164
40. Chen A.H., Song X.D., Luo B.D., and Zou F. Protective and anti-fatigue effects of aspirin against heatstroke in rats. Sheng Li Xue Bao 57 (2005) 446-452
41. Yang C.Y., and Lin M.T. Oxidative stress in rats with heatstroke-induced cerebral ischemia. Stroke 33 (2002) 790-794
42. Niu K.C., Lin K.C., Yang C.Y., and Lin M.T. Protective effects of alpha-tocopherol and mannitol in both circulatory shock and cerebral ischaemia injury in rat heatstroke. Clin Exp Pharmacol Physiol 30 (2003) 745-751
43. Chang C.P., Hsu Y.C., and Lin M.T. Magnolol protects against cerebral ischaemic injury of rat heatstroke. Clin Exp Pharmacol Physiol 30 (2003) 387-392
44. Chan P.H. Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab 21 (2001) 2-14
45. Riedel W., and Maulik G. Fever: an integrated response of the central nervous system to oxidative stress. Mol Cell Biochem 196 (1999) 125-132
46. Suzuki J., Imaizumi S., Kayama T., and Yoshimoto T. Chemiluminescence in hypoxic brain - the second report: cerebral protective effect of mannitol, vitamin E and glucocorticoid. Stroke 16 (1985) 695-700
47. Hall D.M., Buettner G.R., Oberley L.W., Xu L., Matthes R.D., and Gisolfi C.V. Mechanisms of circulatory and intestinal barrier dysfunction during whole body hyperthermia. Am J Physiol Heart Circ Physiol 280 (2001) H509-H521
48. Yang Y.L., Lu K.T., Tsay H.J., Lin C.H., and Lin M.T. Heat shock protein expression protects against death following exposure to heatstroke in rats. Neurosci Lett 252 (1998) 9-12
49. Hung C.H., Chang N.C., Cheng B.C., and Lin M.T. Progressive exercise preconditioning protects against circulatory shock during experimental heatstroke. Shock 23 (2005) 426-433
50. Pavlik A., Aneja I.S., Lexa J., and Al-Zoabi B.A. Identification of cerebral neurons and glial cell types inducing heat shock protein Hsp70 following heat-stress in the rat. Brain Res 973 (2003) 179-189
51. Gabai V.L., and Sherman M.Y. Interplay between molecular chaperones and signaling pathways in survival of heat shock. J Appl Physiol 92 (2002) 1743-1748
52. Yang Y.L., and Lin M.T. Heat shock protein expression protects against cerebral ischemia and monoamine overload in rat heatstroke. Am J Physiol 276 (1999) H1961-H1967
53. Wang J.L., Ke D.S., and Lin M.T. Heat shock pretreatment may protect against heatstroke-induced circulatory shock and cerebral ischemia by reducing oxidative stress and energy depletion. Shock 23 (2005) 161-167
54. Li P.L., Chao Y.M., Chan S.H.H., and Chan J.Y.H. Potentiation of baroreceptor reflex response by heat shock protein 70 in nucleus tractus solitarii confers cardiovascular protection during heatstroke. Circulation 103 (2001) 2114-2119
55. Epstein Y., Moran D.S., Shapiro Y., Sohar E., and Shemer J. Exertional heatstroke: a case series. Med Sci Sports Exerc 31 (1999) 224-228