Flow and aggregation characteristics of thermo-responsive poly(N-isopropylacrylamide) spheres during the phase transition

Chemical Engineering Science

Volumn 61, Issue 19, 2006, Pages 6337-6347

  Zhou, Ming Yu ^a   Chu, Liang Yin ^a   Chen, Wen Mei ^a   Ju, Xiao Jie ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Fluid mechanics; Gels; Laminar flow; Phase transition; Polymers; Thermo responsive poly(N isopropylacrylamide)

Indexed keywords

AGGLOMERATION; CROSSLINKING; FLOW PATTERNS; GELS; HYDROPHILICITY; LAMINAR FLOW; PHASE TRANSITIONS;

HEXAHEDRON; HORIZONTAL PIPE; TETRAHEDRON; THERMO-RESPONSIVE POLY(N-ISOPROPYLACRYLAMIDE);

POLYMERS;

AGGLOMERATION; CROSSLINKING; FLOW PATTERNS; GELS; HYDROPHILICITY; LAMINAR FLOW; PHASE TRANSITIONS; POLYMERS;

EID: 33746976116     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2006.06.010     Document Type: Article

References (34)

1. Arai F., Ng C., Maruyama H., Ichikawa A., EI-Shimy H., and Fukuda T. On chip single-cell separation and immobilization using optical tweezers and thermosensitive hydrogel. Lab on a Chip 5 (2005) 1399-1403
2. Cammas S., Suzuki K., Sone C., Sakurai Y., Kataoka K., and Okano T. Thermo-responsive polymer nanoparticles with core-shell micelle structure as site-specific drug carriers. Journal of Controlled Release 48 (1997) 157-164
3. Caykara T., and Aycicek I. pH-responsive ionic poly(N, N-diethylaminoethyl methacrylate-co-N-vinyl-2-pyrrolidone) hydrogels: synthesis and swelling properties. Journal of Polymer Science Part B-Polymer Physics 43 (2005) 2819-2828
4. Chu L.Y., Park S.H., Yamaguchi T., and Nakao S. Preparation of thermo-responsive core-shell microcapsules with a porous membrane and poly(N-isopropylacrylamide) gates. Journal of Membrane Science 192 (2001) 27-39
5. Chu L.Y., Yamaguchi T., and Nakao S. A molecular-recognition microcapsule for environmental stimuli-responsive controlled release. Advance Materials 14 (2002) 386-389
6. Chu L.Y., Park S.H., Yamaguchi T., and Nakao S. Preparation of small-sized monodispersed thermo-responsive core-shell microcapsules. Langmuir 18 (2002) 1856-1864
7. Chu L.Y., Niitsuma T., Yamaguchi T., and Nakao S. Thermo-responsive transport through porous membranes with grafted PNIPAM gates. A.I.Ch.E. Journal 49 (2003) 896-909
8. Chu L.Y., Li Y., Zhu J.H., Wang H.D., and Liang Y.J. Control of pore size and permeability of a glucose-responsive gating membrane for insulin delivery. Journal of Controlled Release 97 (2004) 43-53
9. Chu L.Y., Li Y., Zhu J.H., and Chen W.M. Negatively thermoresponsive membranes with functional gates driven by zipper-type hydrogen-bonding interactions. Angewandte Chemie International Edition 44 (2005) 2124-2127
10. Chung J.E., Yokoyama M., and Okano T. Inner core segment design for drug delivery control of thermo-responsive polymeric micelles. Journal of Controlled Release 65 (2000) 93-103
11. Eeckman F., Moes A.J., and Amighi K. Surfactant induced drug delivery based on the use of thermosensitive polymers. Journal of Controlled Release 88 (2003) 105-116
12. Hsiue G.H., Hsu S.H., Yang C.C., Lee S.H., and Yang I.K. Preparation of controlled release opthalmic drops for glaucoma therapy using thermosensitive poly-N-isopropylacrylamide. Biomaterials 23 (2002) 457-462
13. Huang G., Gao J., Hu Z.B., John J.V.S., Ponder B.C., and Moro D. Controlled drug release from hydrogel nanoparticle networks. Journal of Controlled Release 94 (2004) 303-311
14. Ichikawa H., and Fukumori Y. A novel positively thermosensitive controlled-release microcapsule with membrane of nano-sized poly(N-isopropylacrylamide) gel dispersed in ethylcellulose matrix. Journal of Controlled Release 63 (2000) 107-119
15. Jin X., and Hsieh Y.L. pH-responsive swelling behavior of poly(vinyl alcohol)/poly(acrylic acid) bi-component fibrous hydrogel membranes. Polymer 46 (2005) 5149-5160
16. Kondo A., and Fukuda H. Preparation of thermo-sensitive magnetic hydrogel microspheres and application to enzyme immobilization. Journal of Fermentation and Bioengineering 84 (1997) 337-341
17. Liu Z.L., Shi M.H., and Dai G.S. Numerical simulation of motion of a solid particle up flowing vertical at the liquid flowfield inside the tube. Journal of the University of Petroleum, China 22 (1998) 79-84
18. Lizawa T., Matsuura Y., and Onohara Y. Synthesis of thermosensitive poly(N-alkylacrylamide) gels and core-shell type gels. Polymer 46 (2005) 8098-8106
19. Nho Y.C., Park S.E., Kim H.I., and Hwang T.S. Oral delivery of insulin using pH-sensitive hydrogels based on polyvinyl alcohol grafted with acrylic acid/methacrylic acid by radiation. Nuclear Instruments and Methods in Physics Research Section B-Beam Interactions with Materials and Atoms 236 (2005) 283-288
20. Okano T., Bae Y.H., Jacobes H., and Kim S.W. Thermally on-off switching polymers for drug permeation and release. Journal of Controlled Release 11 (1990) 3-6
21. Qiu Y., and Park K. Environment-sensitive hydrogels for drug delivery. Advanced Drug Delivery Reviews 53 (2001) 321-339
22. Ramadan A., Skalle P., and Johansen S.T. A mechanistic model to determine the critical flow velocity required to initiate the movement of spherical bed particles in inclined channels. Chemical Engineering Science 58 (2003) 2153-2163
23. Rasmussen K., Willemsen P.R., and Ostgaard K. Barnacle settlement on hydrogels. Biofouling 18 (2002) 177-191
24. Tripodo G., Pitarresi G., Palumbo F.S., Craparo E.F., and Giammona G. UV-photocrosslinking of insulin derivatives to produce hydrogels for drug delivery application. Macromolecular Bioscience 5 (2005) 1074-1084
25. Wang Y.J., Jiang H.L., Hu Y.Q., and Zhu K.J. Biodegradable heparin/ampholytic chitosan complexes for pH-sensitive release of proteins. Acta Polymerica Sinica 4 (2005) 524-528
26. Wei H.L., Yu H.Q., Zhang A.Y., Sun L.G., Hou D.D., and Feng Z.G. Synthesis and characterization of thermosensitive and supramolecular structured hydrogels. Macromolecules 38 (2005) 8833-8839
27. Xiao X.C., Chu L.Y., Chen W.M., Wang S., and Li Y. Positively thermo-sensitive monodisperse core-shell microspheres. Advanced Functional Materials 13 (2003) 847-852
28. Xiao X.C., Chu L.Y., Chen W.M., Wang S., and Xie R. Preparation of submicron-sized monodispersed thermoresponsive core-shell hydrogel microspheres. Langmuir 20 (2004) 5247-5253
29. Yoshida M., Asano M., Suwa T., and Ryoichi K. Thermo- and pH-responsive gels for application in colon delivery systems. Radiation Physics and Chemistry 55 (1999) 677-680
30. Yoshida Y., Kaneko Y., Sakai K., Okano T., Sakurai Y., Bae T.H., and Kim S.W. Positive thermosensitive pulsatile drug release using negative thermosensitive hydrogels. Journal of Controlled Release 32 (1994) 97-102
31. Yoshida Y., Uchida K., Kaneko Y., Sakai K., Kikuchi A., Sakurai Y., and Okano T. Comb-type grafted hydrogels with rapid de-swelling responsive to temperature changes. Nature 374 (1995) 240-242
32. Zhang, S.M., Qu, X.D., Liu, Y.Y., 1994. Powder Engineering. Chinese Architectural Materials Industry Press, Beijing, pp. 14-15.
33. Zhang, X.M., Ren, Z.P., Mei, F.M., 2001. Heat Transfer. Chinese Architectural Industry Press, Beijing, pp. 146-148.
34. Zhang X.Z., and Chu C.C. Fabrication and characterization of microgel-impregnated, thermosensitive PNIPAAm hydrogels. Polymer 46 (2005) 9664-9673