Oral delivery of insulin using pH-sensitive hydrogels based on polyvinyl alcohol grafted with acrylic acid/methacrylic acid by radiation

Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms

Volumn 236, Issue 1-4, 2005, Pages 283-288

  Nho, Young Chang ^a   Park, Sung Eun ^a   Kim, Hyung Il ^b   Hwang, Taek Sung ^b  

^a Korea Atomic Energy Research Institute   (South Korea)

^b Chungnam National University   (South Korea)

Author keywords

Gamma irradiation; Grafting; Hydrogel; Insulin; pH responsive

Indexed keywords

GAMMA RAYS; GRAFTING (CHEMICAL); HYDROGELS; ORGANIC ACIDS; PH EFFECTS; POLYVINYL ALCOHOLS; RADIATION;

ACRYLIC ACID; GASTROINTESTINAL (GI) TRACT; METHACRYLIC ACID; PH-RESPONSIVE;

INSULIN;

EID: 21644446874     PISSN: 0168583X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nimb.2005.03.255     Document Type: Conference Paper

References (11)

1. A.S. Hoffman Adv. Drug Deliv. Rev. 43 2001 3
2. A.M. Lowman, and N.A. Peppas Macromolecules 30 1997 4959
3. A.M. Lowman, M. Morishita, M. Kajita, T. Nagai, and N.A. Peppas Am. Chem. Soc. Am. Pharm. Assoc. 88 1999 933
4. R.A. Siegel J. Controlled Release 8 1988 179
5. Y. Qiu, and K.N. Park Adv. Drug Deliv. Rev. 53 2001 321
6. P. Ravichandran, K.L. Shantha, and P.K. Rao Int. J. Pharm. 154 1997 89
7. B.S. Kim, and N.A. Peppas Int. J. Pharm. 266 2003 29
8. A. Bhattacharya Prog. Polym. Sci. 25 2000 371
9. E. Jabbari, and S. Nozari Eur. Polym. J. 36 2000 2685
10. J.M. Rosiak, and P. Ulanski Radiat. Phys. Chem. 55 1999 139
11. Y.C. Nho, and J.H. Jin J. Appl. Polym. Sci. 63 1997 1101