Linear patterns of Alzheimer's disease mutations along α-helices of presenilins as a tool for PS-1 model construction

Journal of Neurochemistry

Volumn 98, Issue 5, 2006, Pages 1560-1572

  Jozwiak, Krzysztof ^a,b   Zekanowski, Cezary ^c   Filipek, Slawomir ^a  

^a INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

^b MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^c MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Alzheimer's disease; Homology modelling; Molecular model; Mutation patterns; Presenilin; Sequence analysis

Indexed keywords

AMINO ACID; BACTERIORHODOPSIN; PRESENILIN 1; PRESENILIN 2;

ALPHA HELIX; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; DATA BASE; GENETIC POLYMORPHISM; HUMAN; HYDROPHOBICITY; MOLECULAR MODEL; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ANIMALS; CELL-FREE SYSTEM; GENETIC SCREENING; HUMANS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MUTATION; PRESENILIN-1; PROTEIN STRUCTURE, SECONDARY;

EID: 33746934183     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03983.x     Document Type: Article

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