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Volumn 3, Issue 3, 2006, Pages 163-171

Clinical safety of long-acting β2-agonist and inhaled corticosteroid combination therapy in COPD

Author keywords

Chronic obstructive pulmonary disease; COPD; Glucocorticosteroids; Inhaled corticosteroids; Safety

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; BUDESONIDE; CORTICOSTEROID; FLUTICASONE PROPIONATE; FORMOTEROL; GLUCOCORTICOID; HYDROCORTISONE; LONG ACTING DRUG; PLACEBO; SALMETEROL; TRIAMCINOLONE ACETONIDE;

EID: 33746916438     PISSN: 15412555     EISSN: 15412563     Source Type: Journal    
DOI: 10.1080/15412550600830263     Document Type: Review
Times cited : (9)

References (68)
  • 1
    • 33748979747 scopus 로고    scopus 로고
    • BTS guidelines for the management of chronic obstructive pulmonary disease
    • The COPD Guidelines Group of the Standards of Care Committee of the BTS
    • BTS. BTS guidelines for the management of chronic obstructive pulmonary disease. The COPD Guidelines Group of the Standards of Care Committee of the BTS. Thorax 1997; 52:Suppl 5:S1-28.
    • (1997) Thorax , vol.52 , Issue.5 SUPPL.
  • 4
    • 0031001720 scopus 로고    scopus 로고
    • Alternative projections of mortality and disability by cause 1990-2020:Global Burden of Disease Study
    • Murray CJL, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020:Global Burden of Disease Study. Lancet 1997; 349:1498-1504.
    • (1997) Lancet , vol.349 , pp. 1498-1504
    • Murray, C.J.L.1    Lopez, A.D.2
  • 7
    • 0242577949 scopus 로고    scopus 로고
    • Contemporary management of chronic obstructive pulmonary disease:scientific review
    • Sin DD, McAlister FA, Man SF, Anthonisen NR. Contemporary management of chronic obstructive pulmonary disease:scientific review. JAMA 2003; 290:2301-2312.
    • (2003) JAMA , vol.290 , pp. 2301-2312
    • Sin, D.D.1    McAlister, F.A.2    Man, S.F.3    Anthonisen, N.R.4
  • 9
    • 0027462536 scopus 로고
    • Management of chronic obstructive pulmonary disease
    • Ferguson GT, Cherniack RM. Management of chronic obstructive pulmonary disease. N Engl J Med 1993; 328:1017-1022.
    • (1993) N Engl J Med , vol.328 , pp. 1017-1022
    • Ferguson, G.T.1    Cherniack, R.M.2
  • 11
    • 2442516033 scopus 로고    scopus 로고
    • The effect of inhaled tiotropium bromide on lung mucociliary clearance in patients with COPD
    • Hasani A, Toms N, Agnew JE, Sarno M, Harrison AJ, Dilworth P. The effect of inhaled tiotropium bromide on lung mucociliary clearance in patients with COPD. Chest 2004; 125:1726-1734.
    • (2004) Chest , vol.125 , pp. 1726-1734
    • Hasani, A.1    Toms, N.2    Agnew, J.E.3    Sarno, M.4    Harrison, A.J.5    Dilworth, P.6
  • 12
    • 0026497752 scopus 로고
    • The influence of a new beta agonist: Formoterol on mucociliary function
    • Melloni B, Germouty J. The influence of a new beta agonist: formoterol on mucociliary function. Rev Mal Respir 1992; 9:503-507.
    • (1992) Rev Mal Respir , vol.9 , pp. 503-507
    • Melloni, B.1    Germouty, J.2
  • 13
    • 0036907668 scopus 로고    scopus 로고
    • Effect of beta-adrenergic agonists on mucociliary clearance
    • Bennett WD. Effect of beta-adrenergic agonists on mucociliary clearance. J Allergy Clin Immunol 2002; 110:S291-297.
    • (2002) J Allergy Clin Immunol , vol.110
    • Bennett, W.D.1
  • 14
    • 0031915354 scopus 로고    scopus 로고
    • Effect of salmeterol on Haemophilus influenzae infection of respiratorymucosa in vitro
    • Dowling RB, Johnson M, Cole PJ, Wilson R. Effect of salmeterol on Haemophilus influenzae infection of respiratorymucosa in vitro. Eur Respir J 1998; 11:86-90.
    • (1998) Eur Respir J , vol.11 , pp. 86-90
    • Dowling, R.B.1    Johnson, M.2    Cole, P.J.3    Wilson, R.4
  • 16
    • 33746867217 scopus 로고    scopus 로고
    • Chronic Obstructive Pulmonary Disease. National clinical guideline on management of chronic obstructive pulmonary disease in adults in primary and secondary care
    • NICE. Chronic Obstructive Pulmonary Disease. National clinical guideline on management of chronic obstructive pulmonary disease in adults in primary and secondary care. Thorax 2004:59.
    • (2004) Thorax , pp. 59
  • 17
    • 0345188819 scopus 로고    scopus 로고
    • Long-term treatment with inhaled budesonide in persons with mild chronic obstructive pulmonary disease who continue smoking
    • European Respiratory Society Study on Chronic Obstructive Pulmonary Disease.
    • Pauwels RA, Lofdahl CG, Laitinen LA, Schouten JP, Postma DS, Pride NB, Ohlsson SV. Long-term treatment with inhaled budesonide in persons with mild chronic obstructive pulmonary disease who continue smoking. European Respiratory Society Study on Chronic Obstructive Pulmonary Disease. N Engl J Med 1999; 340:1948-1953.
    • (1999) N Engl J Med , vol.340 , pp. 1948-1953
    • Pauwels, R.A.1    Lofdahl, C.G.2    Laitinen, L.A.3    Schouten, J.P.4    Postma, D.S.5    Pride, N.B.6    Ohlsson, S.V.7
  • 18
    • 0034643610 scopus 로고    scopus 로고
    • Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease:the ISOLDE trial
    • Burge PS, Calverley PM, Jones PW, Spencer S, Anderson JA, Maslen TK. Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease:the ISOLDE trial. Br Med J 2000; 320:1297-1303.
    • (2000) Br Med J , vol.320 , pp. 1297-1303
    • Burge, P.S.1    Calverley, P.M.2    Jones, P.W.3    Spencer, S.4    Anderson, J.A.5    Maslen, T.K.6
  • 19
    • 0037425745 scopus 로고    scopus 로고
    • Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease:a randomised controlled trial
    • Calverley P, Pauwels R, Vestbo J, Jones P, Pride N, Gulsvik A, Anderson J, Maden C. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease:a randomised controlled trial. Lancet 2003; 361:449-456.
    • (2003) Lancet , vol.361 , pp. 449-456
    • Calverley, P.1    Pauwels, R.2    Vestbo, J.3    Jones, P.4    Pride, N.5    Gulsvik, A.6    Anderson, J.7    Maden, C.8
  • 20
    • 0032515756 scopus 로고    scopus 로고
    • Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease
    • International COPD Study Group
    • Paggiaro PL, Dahle R, Bakran I, Frith L, Hollingworth K, Efthimiou J. Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease. International COPD Study Group. Lancet 1998; 351:773-780.
    • (1998) Lancet , vol.351 , pp. 773-780
    • Paggiaro, P.L.1    Dahle, R.2    Bakran, I.3    Frith, L.4    Hollingworth, K.5    Efthimiou, J.6
  • 21
    • 0034727828 scopus 로고    scopus 로고
    • Effect of inhaled triamcinolone on the decline in pulmonary function in chronic obstructive pulmonary disease
    • Lung Health Study Research Group. Effect of inhaled triamcinolone on the decline in pulmonary function in chronic obstructive pulmonary disease. N Engl J Med 2000; 343:1902-1909.
    • (2000) N Engl J Med , vol.343 , pp. 1902-1909
  • 23
    • 0034109837 scopus 로고    scopus 로고
    • Inhaled corticosteroids are not beneficial in chronic obstructive pulmonary disease
    • Barnes PJ. Inhaled corticosteroids are not beneficial in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000; 161:342-344; discussion 344.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 342-344
    • Barnes, P.J.1
  • 24
    • 0034094708 scopus 로고    scopus 로고
    • Inhaled corticosteroids are beneficial in chronic obstructive pulmonary disease
    • Calverley PM. Inhaled corticosteroids are beneficial in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000; 161:341-342; discussion 344.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 341-342
    • Calverley, P.M.1
  • 25
    • 18844385261 scopus 로고    scopus 로고
    • A comparison of the risk of hospitalizations due to chronic obstructive pulmonary disease in medicaid patients with various medication regimens, including ipratropium, inhaled corticosteroids, salmeterol, or their combination
    • Rascati KL, Stanford RH, Borker R. A comparison of the risk of hospitalizations due to chronic obstructive pulmonary disease in medicaid patients with various medication regimens, including ipratropium, inhaled corticosteroids, salmeterol, or their combination. Clin Ther 2005; 27:346-354.
    • (2005) Clin Ther , vol.27 , pp. 346-354
    • Rascati, K.L.1    Stanford, R.H.2    Borker, R.3
  • 26
    • 0035880882 scopus 로고    scopus 로고
    • Inhaled corticosteroids and the risk of mortality and readmission in elderly patients with chronic obstructive pulmonary disease
    • Sin DD, Tu JV. Inhaled corticosteroids and the risk of mortality and readmission in elderly patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001; 164:580-584.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 580-584
    • Sin, D.D.1    Tu, J.V.2
  • 27
    • 0037321260 scopus 로고    scopus 로고
    • Inhaled corticosteroids and survival in chronic obstructive pulmonary disease:does the dose matter?
    • Sin DD, Man SF. Inhaled corticosteroids and survival in chronic obstructive pulmonary disease:does the dose matter? Eur Respir J 2003; 21:260-266.
    • (2003) Eur Respir J , vol.21 , pp. 260-266
    • Sin, D.D.1    Man, S.F.2
  • 28
    • 33746868653 scopus 로고    scopus 로고
    • Initial treatment regimen and risk of hospitalisation in patients with chronic obstructive pulmonary disease
    • Anzueto A, McLaughlin T, Standford R. Initial treatment regimen and risk of hospitalisation in patients with chronic obstructive pulmonary disease. J COPD 2004; 1:205-214.
    • (2004) J COPD , vol.1 , pp. 205-214
    • Anzueto, A.1    McLaughlin, T.2    Standford, R.3
  • 30
    • 16544375776 scopus 로고    scopus 로고
    • Combined corticosteroid and long acting beta-agonist in one inhaler for chronic obstructive pulmonary disease
    • Nannini L, Cates CJ, Lasserson TJ, Poole P. Combined corticosteroid and long acting beta-agonist in one inhaler for chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2004; CD003794.
    • (2004) Cochrane Database Syst Rev
    • Nannini, L.1    Cates, C.J.2    Lasserson, T.J.3    Poole, P.4
  • 31
    • 0347473812 scopus 로고    scopus 로고
    • Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease
    • Calverley PM, Boonsawat W, Cseke Z, Zhong N, Peterson S, Olsson H. Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease. Eur Respir J 2003; 22:912-919.
    • (2003) Eur Respir J , vol.22 , pp. 912-919
    • Calverley, P.M.1    Boonsawat, W.2    Cseke, Z.3    Zhong, N.4    Peterson, S.5    Olsson, H.6
  • 32
    • 0141558800 scopus 로고    scopus 로고
    • The efficacy and safety of fluticasone propionate 250mcg/salmeterol 50 mcg combined in the discus inhaler for the treatment of chronic obstrctive pulmonary disease
    • Hanania NA, Darken P, Horstman D, Reisner MD, Lee B, Davis S, Shah T. The efficacy and safety of fluticasone propionate 250mcg/salmeterol 50 mcg combined in the discus inhaler for the treatment of chronic obstrctive pulmonary disease. Chest 2003; 124:834-843.
    • (2003) Chest , vol.124 , pp. 834-843
    • Hanania, N.A.1    Darken, P.2    Horstman, D.3    Reisner, M.D.4    Lee, B.5    Davis, S.6    Shah, T.7
  • 34
    • 0037108632 scopus 로고    scopus 로고
    • Effectiveness of Fluticasone Propionate and Salmeterol Combination Delivered via the Diskus Device in the Treatment of Chronic Obstructive Pulmonary Disease
    • Mahler DA, Wire P, Horstman D, Chang CN, Yates J, Fischer T, Shah T. Effectiveness of Fluticasone Propionate and Salmeterol Combination Delivered via the Diskus Device in the Treatment of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 2002; 166:1084-1091.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 1084-1091
    • Mahler, D.A.1    Wire, P.2    Horstman, D.3    Chang, C.N.4    Yates, J.5    Fischer, T.6    Shah, T.7
  • 35
    • 0037180086 scopus 로고    scopus 로고
    • Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling
    • Roth M, Johnson PR, Rudiger JJ, King GG, Ge Q, Burgess JK, Anderson G, Tamm M, Black JL. Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling. Lancet 2002; 360:1293-1299.
    • (2002) Lancet , vol.360 , pp. 1293-1299
    • Roth, M.1    Johnson, P.R.2    Rudiger, J.J.3    King, G.G.4    Ge, Q.5    Burgess, J.K.6    Anderson, G.7    Tamm, M.8    Black, J.L.9
  • 38
    • 0042007981 scopus 로고    scopus 로고
    • Inhaled corticosteroids with/without long-acting beta-agonists reduce the risk of rehospitalization and death in COPD patients
    • Soriano JB, Kiri VA, Pride NB, Vestbo J. Inhaled corticosteroids with/without long-acting beta-agonists reduce the risk of rehospitalization and death in COPD patients. Am J Respir Med 2003; 2:67-74.
    • (2003) Am J Respir Med , vol.2 , pp. 67-74
    • Soriano, J.B.1    Kiri, V.A.2    Pride, N.B.3    Vestbo, J.4
  • 39
    • 0036798266 scopus 로고    scopus 로고
    • Survival in COPD patients after regular use of fluticasone propionate and salmeterol in general practice
    • Soriano JB, Vestbo J, Pride NB, Kiri V, Maden C, Maier WC. Survival in COPD patients after regular use of fluticasone propionate and salmeterol in general practice. Eur Respir J 2002; 20:819-825.
    • (2002) Eur Respir J , vol.20 , pp. 819-825
    • Soriano, J.B.1    Vestbo, J.2    Pride, N.B.3    Kiri, V.4    Maden, C.5    Maier, W.C.6
  • 41
    • 4344710679 scopus 로고    scopus 로고
    • The TORCH (towards a revolution in COPD health) survival study protocol
    • Vestbo J. The TORCH (towards a revolution in COPD health) survival study protocol. Eur Respir J 2004; 24:206-210.
    • (2004) Eur Respir J , vol.24 , pp. 206-210
    • Vestbo, J.1
  • 42
    • 0020538546 scopus 로고
    • Steroid-induced fractures and bone loss in patients with asthma
    • Adinoff AD, Hollister JR. Steroid-induced fractures and bone loss in patients with asthma. N Engl J Med 1983; 309:265-268.
    • (1983) N Engl J Med , vol.309 , pp. 265-268
    • Adinoff, A.D.1    Hollister, J.R.2
  • 43
    • 0035097139 scopus 로고    scopus 로고
    • Extrapulmonary effects of chronic obstructive pulmonary disease
    • Gross NJ. Extrapulmonary effects of chronic obstructive pulmonary disease. Curr Opin Pulm Med 2001; 7:84-92.
    • (2001) Curr Opin Pulm Med , vol.7 , pp. 84-92
    • Gross, N.J.1
  • 44
    • 1642447735 scopus 로고    scopus 로고
    • Fracture Risk Associated with Inhaled Corticosteroid Use in Chronic Obstructive Pulmonary Disease
    • Lee TA, Weiss KB. Fracture Risk Associated with Inhaled Corticosteroid Use in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 2004; 169:855-859.
    • (2004) Am J Respir Crit Care Med , vol.169 , pp. 855-859
    • Lee, T.A.1    Weiss, K.B.2
  • 46
  • 47
    • 1242284409 scopus 로고    scopus 로고
    • Impact of long-term inhaled corticosteroid therapy on bone mineral density:results of a meta-analysis
    • quiz 207-208, 267
    • Halpern MT, Schmier JK, Van Kerkhove MD, Watkins M, Kalberg CJ. Impact of long-term inhaled corticosteroid therapy on bone mineral density:results of a meta-analysis. Ann Allergy Asthma Immunol 2004; 92:201-207; quiz 207-208, 267.
    • (2004) Ann Allergy Asthma Immunol , vol.92 , pp. 201-207
    • Halpern, M.T.1    Schmier, J.K.2    Van Kerkhove, M.D.3    Watkins, M.4    Kalberg, C.J.5
  • 48
    • 4644372018 scopus 로고    scopus 로고
    • Fracture incidence from clinical trials of fluticasone propionate alone or in combination with salmeterol in the treatment of chronic obstructive pulmonary disease
    • Knobil K, Watkin S, Yates J, Darken P, Wire P. Fracture incidence from clinical trials of fluticasone propionate alone or in combination with salmeterol in the treatment of chronic obstructive pulmonary disease. Chest 2002; 122:43s.
    • (2002) Chest , vol.122
    • Knobil, K.1    Watkin, S.2    Yates, J.3    Darken, P.4    Wire, P.5
  • 49
    • 13844314313 scopus 로고    scopus 로고
    • The risk of nonvertebral fracture related to inhaled corticosteroid exposure among adults with chronic respiratory disease
    • Johannes CB, Schneider GA, Dube TJ, Alfredson TD, Davis KJ, Walker AM. The risk of nonvertebral fracture related to inhaled corticosteroid exposure among adults with chronic respiratory disease. Chest 2005; 127:89-97.
    • (2005) Chest , vol.127 , pp. 89-97
    • Johannes, C.B.1    Schneider, G.A.2    Dube, T.J.3    Alfredson, T.D.4    Davis, K.J.5    Walker, A.M.6
  • 50
    • 84921622369 scopus 로고    scopus 로고
    • Inhaled corticosteroid effects on bone metabolism in asthma and mild chronic obstructive pulmonary disease
    • Jones A, Fay JK, Burr M, Stone M, Hood K, Roberts G. Inhaled corticosteroid effects on bone metabolism in asthma and mild chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2002; CD003537.
    • (2002) Cochrane Database Syst Rev
    • Jones, A.1    Fay, J.K.2    Burr, M.3    Stone, M.4    Hood, K.5    Roberts, G.6
  • 51
    • 0141748410 scopus 로고    scopus 로고
    • A population based case-control study of cataract and inhaled corticosteroids
    • Smeeth L, Boulis M, Hubbard R, Fletcher AE. A population based case-control study of cataract and inhaled corticosteroids. Br J Ophthalmol 2003; 87:1247-1251.
    • (2003) Br J Ophthalmol , vol.87 , pp. 1247-1251
    • Smeeth, L.1    Boulis, M.2    Hubbard, R.3    Fletcher, A.E.4
  • 52
  • 53
    • 0030048729 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of inhaled glucocorticoids
    • Johnson M. Pharmacodynamics and pharmacokinetics of inhaled glucocorticoids. J Allergy Clin Immunol 1996; 97:169-176.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 169-176
    • Johnson, M.1
  • 55
    • 0034854302 scopus 로고    scopus 로고
    • Beclomethasone dipropionate:absolute bioavailability, pharmacokinetics and metabolism following intravenous, oral, intranasal and inhaled administration in man
    • Daley-Yates PT, Price AC, Sisson JR, Pereira A, Dallow N. Beclomethasone dipropionate:absolute bioavailability, pharmacokinetics and metabolism following intravenous, oral, intranasal and inhaled administration in man. Br J Clin Pharmacol 2001; 51:400-409.
    • (2001) Br J Clin Pharmacol , vol.51 , pp. 400-409
    • Daley-Yates, P.T.1    Price, A.C.2    Sisson, J.R.3    Pereira, A.4    Dallow, N.5
  • 56
    • 0242575103 scopus 로고    scopus 로고
    • State of the art in beta2-agonist therapy:a safety review of long-acting agents
    • Rabe KF. State of the art in beta2-agonist therapy:a safety review of long-acting agents. Int J Clin Pract 2003; 57:689-697.
    • (2003) Int J Clin Pract , vol.57 , pp. 689-697
    • Rabe, K.F.1
  • 57
    • 0033940928 scopus 로고    scopus 로고
    • Systemic effects of formoterol and salmeterol:a dose-response comparison in healthy subjects
    • Guhan AR, Cooper S, Oborne J, Lewis S, Bennett J, Tattersfield AE. Systemic effects of formoterol and salmeterol:a dose-response comparison in healthy subjects. Thorax 2000; 55:650-656.
    • (2000) Thorax , vol.55 , pp. 650-656
    • Guhan, A.R.1    Cooper, S.2    Oborne, J.3    Lewis, S.4    Bennett, J.5    Tattersfield, A.E.6
  • 58
    • 4344661580 scopus 로고    scopus 로고
    • A benefit-risk assessment of inhaled long-acting beta2-agonists in the management of obstructive pulmonary disease
    • Sovani MP, Whale CI, Tattersfield AE. A benefit-risk assessment of inhaled long-acting beta2-agonists in the management of obstructive pulmonary disease. Drug Saf 2004; 27:689-715.
    • (2004) Drug Saf , vol.27 , pp. 689-715
    • Sovani, M.P.1    Whale, C.I.2    Tattersfield, A.E.3
  • 59
    • 0031810916 scopus 로고    scopus 로고
    • Cardiac effects of formoterol and salmeterol in patients suffering from COPD with preexisting cardiac arrhythmias and hypoxemia
    • Cazzola M, Imperatore F, Salzillo A, Di Perna F, Calderaro F, Imperatore A, Matera MG. Cardiac effects of formoterol and salmeterol in patients suffering from COPD with preexisting cardiac arrhythmias and hypoxemia. Chest 1998; 114:411-415.
    • (1998) Chest , vol.114 , pp. 411-415
    • Cazzola, M.1    Imperatore, F.2    Salzillo, A.3    Di Perna, F.4    Calderaro, F.5    Imperatore, A.6    Matera, M.G.7
  • 60
    • 2942744546 scopus 로고    scopus 로고
    • Cardiovascular effects of beta-agonists in patients with asthma and COPD:A meta-analysis
    • Salpeter SR, Ormiston TM, Salpeter EE. Cardiovascular effects of beta-agonists in patients with asthma and COPD:A meta-analysis. Chest 2004; 125:2309-2321.
    • (2004) Chest , vol.125 , pp. 2309-2321
    • Salpeter, S.R.1    Ormiston, T.M.2    Salpeter, E.E.3
  • 61
    • 0035696857 scopus 로고    scopus 로고
    • Safety of formoterol Turbuhaler at cumulative dose of 90 microg in patients with acute bronchial obstruction
    • Malolepszy J, Boszormenyi Nagy G, Selroos O, Larsso P, Brander R. Safety of formoterol Turbuhaler at cumulative dose of 90 microg in patients with acute bronchial obstruction. Eur Respir J 2001; 18:928-934.
    • (2001) Eur Respir J , vol.18 , pp. 928-934
    • Malolepszy, J.1    Boszormenyi Nagy, G.2    Selroos, O.3    Larsso, P.4    Brander, R.5
  • 63
    • 33746932594 scopus 로고    scopus 로고
    • Cardiovascular (CV) pharmacodynamics (PD) and pharmacokinetics (PK) of salmeterol (SALM) following single and repeated dosing in chronic obstructive pulmonary disease (COPD)
    • Daley-Yates PT, Majer-Teboul C, Prieur A, Minini P, Bidault R, Maison-Blanche P, Finck-Brentano C. Cardiovascular (CV) pharmacodynamics (PD) and pharmacokinetics (PK) of salmeterol (SALM) following single and repeated dosing in chronic obstructive pulmonary disease (COPD). Am J Respir Crit Care Med 2003; 167:A319.
    • (2003) Am J Respir Crit Care Med , vol.167
    • Daley-Yates, P.T.1    Majer-Teboul, C.2    Prieur, A.3    Minini, P.4    Bidault, R.5    Maison-Blanche, P.6    Finck-Brentano, C.7
  • 64
    • 23744435643 scopus 로고    scopus 로고
    • Inhaled beta2-adrenoceptor agonists:cardiovascular safety in patients with obstructive lung disease
    • Cazzola M, Matera MG, Donner CF. Inhaled beta2-adrenoceptor agonists:cardiovascular safety in patients with obstructive lung disease. Drugs 2005; 65:1595-1610.
    • (2005) Drugs , vol.65 , pp. 1595-1610
    • Cazzola, M.1    Matera, M.G.2    Donner, C.F.3
  • 65
    • 4143090018 scopus 로고    scopus 로고
    • Salmeterol multi-center asthma research trial (SMART):Results from an interim analysis
    • Knobil K, Yancey S, Kral K, Rickard K. Salmeterol multi-center asthma research trial (SMART):Results from an interim analysis. Chest 2003; 124:335S.
    • (2003) Chest , vol.124
    • Knobil, K.1    Yancey, S.2    Kral, K.3    Rickard, K.4
  • 66
    • 33144476873 scopus 로고    scopus 로고
    • The Salmeterol Multicenter Asthma Research Trial:A comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol
    • Nelson HS, Weiss ST, Bleecker ER, Yancey SW, Dorinsky PM. The Salmeterol Multicenter Asthma Research Trial:a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest 2006; 129:15-26.
    • (2006) Chest , vol.129 , pp. 15-26
    • Nelson, H.S.1    Weiss, S.T.2    Bleecker, E.R.3    Yancey, S.W.4    Dorinsky, P.M.5
  • 68
    • 29144531153 scopus 로고    scopus 로고
    • Safety of long-acting beta-agonists - An urgent need to clear the air
    • Martinez FD. Safety of long-acting beta-agonists - an urgent need to clear the air. N Engl J Med 2005; 353:2637-2639.
    • (2005) N Engl J Med , vol.353 , pp. 2637-2639
    • Martinez, F.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.