The bogorol family of antibiotics: Template-based structure elucidation and a new approach to positioning enantiomeric pairs of amino acids

Journal of Organic Chemistry

Volumn 71, Issue 16, 2006, Pages 6031-6037

  Barsby, Todd ^a,b   Warabi, Kaoru ^a   Sørensen, Dan ^a,c   Zimmerman, William T ^a   Kelly, Michael T ^d   Andersen, Raymond J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF ONTARIO INSTITUTE OF TECHNOLOGY   (Canada)

^c MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACID-CATALYZED HYDROLYSIS; BOGOROL A; BOGOROL CATIONIC PEPTIDE; PREDILECTION;

AMINO ACIDS; BACTERIA; ESCHERICHIA COLI; GAS CHROMATOGRAPHY; HYDROLYSIS; MASS SPECTROMETERS; MOLECULAR STRUCTURE; POLYPEPTIDES;

ANTIBIOTICS;

2 HYDROXY 3 METHYLVALERIC ACID; AMINO ACID; ANTIBIOTIC AGENT; BOGOROL A; BOGOROL B; BOGOROL C; BOGOROL D; BOGOROL E; CATION; DEXTRO AMINO ACID; LEUCINE; LYSINE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE; VALINE; VALINOL;

ACIDITY; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; DRUG DEGRADATION; DRUG SELECTIVITY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ENANTIOMER; ESCHERICHIA COLI; GAS CHROMATOGRAPHY; HYDROLYSIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; STEREOCHEMISTRY; TANDEM MASS SPECTROMETRY; VANCOMYCIN RESISTANT ENTEROCOCCUS;

AMINO ACID SEQUENCE; AMINO ACIDS; ANTI-BACTERIAL AGENTS; BACILLUS; HYDROLYSIS; MICROBIAL VIABILITY; MOLECULAR SEQUENCE DATA; PEPTIDES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TANDEM MASS SPECTROMETRY;

EID: 33746903170     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo060667p     Document Type: Article

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