Meconium analysis to detect fetal exposure to neurotoxicants

Archives of Disease in Childhood

Volumn 91, Issue 8, 2006, Pages 628-629

  Ostrea Jr , E M ^a   Bielawski, D M ^a   Posecion Jr , N C ^a  

^a HUTZEL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; CADMIUM; CHLORDANE; CHLORPHENOTANE; CHLORPYRIFOS; COCAINE; DIMPYLATE; HEAVY METAL; HEXACHLOROBENZENE; HEXACHLOROCYCLOHEXANE; ILLICIT DRUG; LEAD; MALATHION; MERCURY; MORPHINE; NEUROTOXIN; PARATHION; PENTACHLOROBENZENE; PESTICIDE; POLYCHLORINATED BIPHENYL; XENOBIOTIC AGENT;

AMNION FLUID ANALYSIS; ANALYTIC METHOD; CORRELATION ANALYSIS; DIAGNOSTIC VALUE; DRUG METABOLISM; EXPOSURE VARIABLE; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; MECONIUM; MECONIUM ANALYSIS; NEUROTOXICITY; NONHUMAN; OUTCOME ASSESSMENT; POLLUTION; POLLUTION MONITORING; PRENATAL DIAGNOSIS; PRENATAL EXPOSURE; PRENATAL PERIOD; PREVALENCE; PRIORITY JOURNAL; REVIEW;

ENVIRONMENTAL POLLUTANTS; FEMALE; HUMANS; MECONIUM; NEUROTOXICITY SYNDROMES; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 33746891502     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/adc.2006.097956     Document Type: Review

References (10)

1. Ostrea EM Jr. Testing for illicit drugs and other agents in the neonate. A review of laboratory methods and the role of meconium analysis. In: Moyer VA, eds. Current problems in pediatrics. St Louis, MO: Mosby, 1999;29:37-60.
2. Ostrea EM Jr, Morales V, Ngaumgna E, et al. Prevalence of fetal exposure to environmental toxins as determined by meconium analysis. Neurotoxicology 2002;23:329-39.
3. Hong Z, Günter M, Randow FFE. Meconium: a matrix reflecting potential fetal exposure to organochlorine pesticides and its metabolites. Ecotoxicol Environ Safety 2002;51:60-4.
4. Whyatt RM, Barr DB. Measurement of organophosphate metabolites in postpartum meconium as a potential biomarker of prenatal exposure: a validation study. Environ Health Perspect 2001;109:417-20.
5. Bielawski D, Ostrea E Jr, Posecion N, et al. Detection of several classes of pesticides and metabolites in meconium by gas chromatography/mass spectrometry. Chromatographia 2005;62:623-9.
6. Ortega Garcia JA, Carrizo Gallardo D, Ferris i Tortajada J, et al. Meconium and neurotoxicants: searching for a prenatal exposure timing. Arch Dis Child 2006;91:642-6.
7. Ostrea EM Jr, Bielawski DM, Posecion NC Jr, et al. econium-the best matrix to detect fetal exposure to environmental pesticide/herbicide. Abstract M2C01. International Society of Exposure Analysis, Philadelphia, PA, 2004.
8. Silvestre MA, Lucena J, Ostrea EM. The effect of timing, dosage and duration or morphine intake during pregnancy on the amount of morphine in meconium in a rat model. Biol Neonate 1997;72:112-17.
9. Ostrea EM Jr, Romero A, Knapp DK, et al. Postmortem analysis of meconium in early gestation human fetuses exposed to cocaine: clinical implications. J Pediatr 1994;124:477.
10. Ostrea EM Jr, Knapp K, Tannenbaum L, et al. Estimates of illicit drug use during pregnancy by maternal interview, hair analysis, and meconium analysis. J Pediatr 2001;138:344-8.