Coronary flow reserve and heart failure in experimental coxsackievirus myocarditis. A transthoracic Doppler echocardiography study

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 291, Issue 2, 2006, Pages

  Saraste, Antti ^a   Kytö, Ville ^a,b   Saraste, Markku ^a   Vuorinen, Tytti ^b   Hartiala, Jaakko ^a   Saukko, Pekka ^b  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

Coronary microcirculation; Coxsackievirus B3; Fractional shortening; Left coronary artery

Indexed keywords

ADOLESCENT; ANIMAL MODEL; ARTICLE; CORONARY ARTERY BLOOD FLOW; COXSACKIE VIRUS; DOPPLER ECHOCARDIOGRAPHY; FLOW RATE; HEART FAILURE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS MYOCARDITIS;

ANIMALS; CORONARY CIRCULATION; COXSACKIEVIRUS INFECTIONS; ECHOCARDIOGRAPHY; HEART FAILURE, CONGESTIVE; HEART FUNCTION TESTS; MALE; MICE; MICE, INBRED BALB C; MYOCARDITIS; MYOCARDIUM; VENTRICULAR FUNCTION, LEFT;

EID: 33746814814     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01375.2005     Document Type: Article

References (25)

1. Arola A, Kalimo H, Ruuskanen O, and Hyypiä T. Experimental myocarditis induced by two different coxsackievirus B3 variants: aspects of pathogenesis and comparison of diagnostic methods. J Med Virol 47: 251-259, 1995.
2. Caiati C, Montaldo C, Zedda N, Montisci R, Ruscazio M, Lai G, Cadeddu M, Meloni L, and Iliceto S. Validation of a new noninvasive method (contrast-enhanced transthoracic second harmonic echo Doppler) for the evaluation of coronary flow reserve: comparison with intracoronary Doppler flow wire. J Am Coll Cardiol 34: 1193-1200, 1999.
3. Choy JC, Lui AH, Moien-Afshari F, Wei K, Yanagawa B, McManus BM, and Laher I. Coxsackievirus B3 infection compromises endothelial-dependent vasodilatation of coronary resistance arteries. J Cardiovasc Pharmacol 43: 39-47, 2004.
4. Dong R, Liu P, Wee L, Butany J, and Sole MJ. Verapamil ameliorates the clinical and pathological course of murine myocarditis. J Clin Invest 90: 2022-2030, 1992.
5. Factor SM, Minase T, Cho S, Dominitz R, and Sonnenblick EH. Microvascular spasm in the cardiomyopathic Syrian hamster: a preventable cause of focal myocardial necrosis. Circulation 66: 342-534, 1981.
6. Feldman AM and McNamara D. Myocarditis. N Engl J Med 343: 1388-1398, 2000.
7. Gan L, Wikström J, Bergström G, and Wandt B. Non-invasive imaging of coronary arteries in living mice using high-resolution echocardiography. Scand Cardiovasc J 38: 121-126, 2004.
8. Gardin JM, Siri FM, Kitsis RN, Edwards JG, and Leinwand LA. Echocardiographic assessment of left ventricular mass and systolic function in mice. Circ Res 76: 907-914, 1995.
9. Gavin JB, Maxwell L, and Edgar SG. Microvascular involvement in cardiac Pathology. J Mol Cell Cardiol 30: 2531-2540, 1998.
10. Hirata K, Shimada K, Watanabe H, Muro T, Yoshiyama M, Takeuchi K, Hozumi T, and Yoshikawa J. Modulation of coronary flow velocity reserve by gender, menstrual cycle and hormone replacement therapy. J Am Coll Cardiol 38: 1879-1884, 2001.
11. Hozumi T, Yoshida K, Akasaka T, Asami Y, Ogata Y, Takagi T, Kaji S, Kawamoto T, Uedo Y, and Morioka S. Noninvasive assessment of coronary flow velocity and coronary flow velocity reserve in the left anterior descending coronary artery by Doppler echocardiography, comparison with invasive technique. J Am Coll Cardiol 32: 1251-1259, 1998.
12. Klein RM, Schwarzkopf B, and Strauer BE. Evidence of endothelial dysfunction of epicardial coronary arteries in patients with immunohistochemically proven myocarditis. Am Heart J 136: 389-397, 1998.
13. Klingel K, Rieger P, Mall G, Selinka HC, Huber M, and Kandolf R. Visualization of enteroviral replication in myocardial tissue by ultrastructural in situ hybridisation: identification of target cells and cytopathic effects. Lab Invest 78: 1227-1237, 1998.
14. Lee JK, Zaidi SH, Liu P, Dawood F, Cheach AYL, Wen WH, Saiki Y, and Rabinovitch M.. A serine elastase inhibitor reduces inflammation and fibrosis and preserves cardiac function after experimentally-induced murine myocarditis. Nat Med 4: 1383-1391, 1998.
15. Martino TA, Liu P, and Sole MJ. Viral infection and the pathogenesis of dilated cardiomyopathy. Circ Res 74: 182-188, 1994.
16. Saraste A, Arola A, Vuorinen T, Kytö V, Kallajoki M, Pulkki K, Voipio-Pulkki LM, and Hyypia T. Cardiomyocyte apoptosis in experimental coxsackievirus B3 myocarditis. Cardiovasc Pathol 12: 255-262, 2003.
17. Saraste M, Koskenvuo J, Knuuti J, Toikka J, Laine H, Niemi P, Sakuma H, and Hartiala J. Coronary flow reserve: measurement with transthoracic Doppler echocardiography is reproducible and comparable with positron emission tomography. Clin Physiol 21: 114-122, 2001.
18. Saraste M, Vesalainen RK, Ylitalo A, Saraste A, Koskenvuo JW, Toikka JO, Vaittine MA, Hartiaka JJ, and Airaksinen KE. Transthoracic Doppler echocardiography as a noninvasive tool to assess coronary artery stenoses-a comparison with quantitative coronary angiography. J Am Soc Echocardiogr 18: 679-685, 2005.
19. Shirani J, Ilercil A, Chandra M, Jelicks LA, and Tanowitz HB. Cardiovascular imaging in clinical and experimental acute infectious myocarditis. Front Biosci 8: e323-e36, 2003.
20. Silver MA and Kowalczyk D. Coronary microvascular narrowing in acute murine coxsackievirus B3 myocarditis. Am Heart J 118: 173-174, 1989.
21. Tanaka N, Dalton N, Mao L, Rockman HA, Peterson KL, Gottshall KR, Hunter JJ, Chien KR, and Ross J Jr. Transthoracic echocardiography in models of cardiac disease in the mouse. Circulation 94: 1109-1117, 1996.
22. Vallbracht KB, Schwimmbeck PL, Kühl U, Rauch U, Seeberg B, and Schultheiss HP. Differential aspects of endothelial function of the coronary microcirculation considering myocardial virus persistence, endothelial activation, and myocardial leukocyte infiltrates. Circulation 111: 1784-1791, 2005.
23. Voci P, Pizzuto F, and Romeo F. Coronary flow: a new asset for the echo lab? Eur Heart J 25: 1867-1879, 2004.
24. Wikström J, Grönros J, Bergström G, and Gan L. Functional and morphologic imaging of coronary atherosclerosis in living mice using high-resolution color Doppler echocardiography and ultrasound biomicroscopy. J Am Coll Cardiol 46: 720-727, 2005.
25. Zanone MM, Favaro E, Conaldi PG, Greening J, Bottelli A, Perin PC, Klein NJ, Peakman M, and Camussi G. Persistent infection of human microvascular endothelial cells by coxsackie B viruses increased expression of adhesion molecules. J Immunol 171: 438-446, 2003.