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Volumn 1, Issue 2, 2000, Pages

The sequence of human chromosome 21 and implications for research into Down syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; CHROMOSOME 21; DISEASE MODEL; DOWN SYNDROME; GENE EXPRESSION PROFILING; GENETICS; HUMAN; MOUSE; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PHENOTYPE; REVIEW; SEQUENCE HOMOLOGY;

EID: 33746774817     PISSN: 14656906     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (57)

References (40)
  • 2
    • 0000521855 scopus 로고
    • Down syndrome (trisomy 21 )
    • Edited by Scriver ÇA et al. New York: McGraw Hill;
    • Epstein CJ: Down syndrome (trisomy 21 ). In Metabolic and Molecular Bases of Inherited Disease. Edited by Scriver ÇA et al. New York: McGraw Hill; 1995:749-794.
    • (1995) Metabolic and Molecular Bases of Inherited Disease , pp. 749-794
    • Epstein, C.J.1
  • 6
    • 0031593214 scopus 로고    scopus 로고
    • Clonability and gene distribution on human chromosome 21: Reflections of junk DNA content?
    • Gardiner K: Clonability and gene distribution on human chromosome 21: reflections of junk DNA content? Gene 1997, 205:39-46.
    • (1997) Gene , vol.205 , pp. 39-46
    • Gardiner, K.1
  • 8
    • 0027947017 scopus 로고
    • Digitized and differentially shaded human chromosome ideograms for genomic applications
    • Francke U: Digitized and differentially shaded human chromosome ideograms for genomic applications. Cytogenet Cell Genet 1994,65:206-219.
    • (1994) Cytogenet Cell Genet , vol.65 , pp. 206-219
    • Francke, U.1
  • 9
    • 0030603223 scopus 로고    scopus 로고
    • Identification of the gene-richest bands in human chromosomes
    • Saccone S, Caccio S, Kusuda J, Andreozzi L, Bernard! G: Identification of the gene-richest bands in human chromosomes. Gene 1996, 174:85-94.
    • (1996) Gene , vol.174 , pp. 85-94
    • Saccone, S.1    Caccio, S.2    Kusuda, J.3    Andreozzi, L.4    Bernard, G.5
  • 11
    • 33746755804 scopus 로고    scopus 로고
    • DbEST [http://www.ncbi.nlm.nih.gov/dbEST/index.html].
    • DbEST
  • 13
    • 33746726310 scopus 로고    scopus 로고
    • Eleanor Roosevelt Institute [http://www-eri.uchsc.edu/].
  • 17
    • 0022473014 scopus 로고
    • LFA-I immunodeficiency disease: Definition of the genetic defect and chromosomal mapping of alpha and beta subunits of the lymphocyte function-associated antigen I (LFA-I) by complementation in hybrid cells
    • Martin SD, Morton CC, Anderson DC, Springer TA: LFA-I immunodeficiency disease: definition of the genetic defect and chromosomal mapping of alpha and beta subunits of the lymphocyte function-associated antigen I (LFA-I) by complementation in hybrid cells. jExpMed 1986, 164:855-867.
    • (1986) JExpMed , vol.164 , pp. 855-867
  • 18
    • 0021967729 scopus 로고
    • Increased adhesiveness of trisomy 21 cells and atrioventricular canal malformations in Down syndrome: A stochastic model
    • Kurnit DM, Aldridge JF, Matsuoka R, Matthysse S: Increased adhesiveness of trisomy 21 cells and atrioventricular canal malformations in Down syndrome: a stochastic model. Am J Med Genet 1985,20:385-399.
    • (1985) Am J Med Genet , vol.20 , pp. 385-399
  • 19
    • 0033515102 scopus 로고    scopus 로고
    • Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression
    • Sutherland ML Williams SH, Abedi R, Overbeek PA, Pfaffinger PJ, Noebels JU Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression. Proc Not/ Acad Sei USA 1999,96:2451-2455.
    • (1999) Proc Not/ Acad Sei USA , vol.96 , pp. 2451-2455
    • Williams Sh, S.M.L.1    Abedi, R.2    Overbeek, P.A.3    Pfaffinger, P.J.4    Noebels, J.U.5
  • 20
    • 0345051044 scopus 로고    scopus 로고
    • Normalization and subtraction: Two approaches to facilitate gene discovery
    • Bonaldo MF, Lennon G, Scares MB: Normalization and subtraction: two approaches to facilitate gene discovery. Genome Res 1996,6:791-806.
    • (1996) Genome Res , vol.6 , pp. 791-806
  • 21
    • 0024206815 scopus 로고
    • An immunochemical analysis of the distribution of a brain-specific polypeptide, PEP-l9
    • Ziai MR, Sangameswaran L, HempsteadJL, Danho W, Morgan Jl: An immunochemical analysis of the distribution of a brain-specific polypeptide, PEP-l9.jNeurocnem 1988, 51:1771-1776.
    • (1988) JNeurocnem , vol.51 , pp. 1771-1776
  • 22
    • 0032211687 scopus 로고    scopus 로고
    • Two isoforms of a human intersectin (ITSN) protein are produced by brain-specific alternative splicing in a stop codon
    • Guipponi M, Scott HS, Chen H, Schebesta A, Rossier C, Antonarakis SE: Two isoforms of a human intersectin (ITSN) protein are produced by brain-specific alternative splicing in a stop codon. Genomics 1998,53:369-376.
    • (1998) Genomics , vol.53 , pp. 369-376
    • Guipponi, M.1    Scott, H.S.2    Chen, H.3    Schebesta, A.4    Rossier, C.5    Antonarakis, S.E.6
  • 23
    • 0031964775 scopus 로고    scopus 로고
    • DSCAM: A novel member of the immunoglobulin superfamily maps in a Down syndrome region and is involved in the development of the nervous system
    • Yamakawa K, Huot YK, Haendelt MA, Hubert R, Chen XN, Lyons GE, KorenbergJR: DSCAM: a novel member of the immunoglobulin superfamily maps in a Down syndrome region and is involved in the development of the nervous system. Hum Mol Genet 1998, 7:227-237.
    • (1998) Hum Mol Genet , vol.7 , pp. 227-237
  • 24
    • 0034681998 scopus 로고    scopus 로고
    • Criteria for gene identification and features of genome organization: Analysis of 6.5 Mb of DNA sequence from human chromosome 21
    • Slavov D, Hattori M, Sakaki Y, Rosenthal A, Shimizu N, Minoshima S, Kudoh J, Yaspo M, Ramser J, Reinhardt et al.: Criteria for gene identification and features of genome organization: analysis of 6.5 Mb of DNA sequence from human chromosome 21. Gene 2000, 247:215-232.
    • (2000) Gene , vol.247 , pp. 215-232
  • 25
    • 10244239321 scopus 로고    scopus 로고
    • Life with 6000 Genes
    • Goffeau A, Barrell EG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M et al.: Life with 6000 Genes. Science 1996.274:546-567.
    • (1996) Science , vol.274 , pp. 546-567
  • 26
    • 0032509302 scopus 로고    scopus 로고
    • Genome sequence of the nematode C. etegans: A platform for investigating biology
    • The C e/egons Sequencing Consortium: Genome sequence of the nematode C. etegans: a platform for investigating biology. Sdence 1998. 282:2012-2018.
    • (1998) Sdence , vol.282 , pp. 2012-2018
  • 28
    • 0033403913 scopus 로고    scopus 로고
    • Perfect conserved linkage across the entire mouse chromosome 10 region homologous to human chromosome 21
    • Wiltshire T, Pletcher M, Cole SE, Villaneuva M, Birren B, Lehoczky J, Dewar K, Reeves RH: Perfect conserved linkage across the entire mouse chromosome 10 region homologous to human chromosome 21. Genome Res 1999, 9:1214-1222
    • (1999) Genome Res , vol.9 , pp. 1214-1222
  • 31
    • 0003043137 scopus 로고    scopus 로고
    • Down syndrome: Neuropsychology and animal models
    • Crnic LS, Pennington BF: Down syndrome: neuropsychology and animal models. Progr Infancy Res 2000, 1:69-111.
    • (2000) Progr Infancy Res , vol.1 , pp. 69-111
    • Crnic, L.S.1    Pennington, B.F.2
  • 32
    • 0033407499 scopus 로고    scopus 로고
    • Motor dysfunction in a mouse model for Down syndrome
    • Costa ACS, Walsh K, Davisson MT: Motor dysfunction in a mouse model for Down syndrome. Physiol Behov 1999, 68:1-10.
    • (1999) Physiol Behov , vol.68 , pp. 1-10
  • 33
    • 0033528770 scopus 로고    scopus 로고
    • A murine model for Down syndrome shows reduced responsiveness to pain
    • Martinez-Cué C, Baamonde C, Lumbreras MA, Villina IF, Dierssen M, Florez J: A murine model for Down syndrome shows reduced responsiveness to pain. NeuroReport 1999, 10:1119-1122.
    • (1999) NeuroReport , vol.10 , pp. 1119-1122
  • 34
    • 10544243361 scopus 로고    scopus 로고
    • Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome
    • Holtzman DM, Santucci D, Kilbridge J, Chua-Couzens J, Fontana DJ, Daniels SE, Johnson RM, Chen K, Sun Y, Carlson E et al: Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome. Proc Nat/ Acad Sei USA 1996,93:13333-13338.
    • (1996) Proc Nat/ Acad Sei USA , vol.93 , pp. 13333-13338
  • 35
    • 0034097607 scopus 로고    scopus 로고
    • Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome
    • Granholm AC, Sanders LA, Crnic LS: Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome. Exp Neural 2000, 161:647-663.
    • (2000) Exp Neural , vol.161 , pp. 647-663
  • 36
    • 0033970177 scopus 로고    scopus 로고
    • Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice
    • Kurt MA, Davies DC. Kidd M, Kierssen M, Flörez J: Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice. Brain Res 2000. 858:191-197.
    • (2000) Brain Res , vol.858 , pp. 191-197
  • 37
    • 18244415365 scopus 로고    scopus 로고
    • Hippocampat volume and neuronal number in Ts65Dn mice: A murine model of Down syndrome
    • Insausti AM, Megias M, Crespo D, Cruz-Orive LM, Dierssen M, Vallina TF, Insausti R, Florez J, Vallina TF: Hippocampat volume and neuronal number in Ts65Dn mice: a murine model of Down syndrome. NeurosciLett 1998, 253:175-178.
    • (1998) NeurosciLett , vol.253 , pp. 175-178
  • 38
    • 0031055509 scopus 로고    scopus 로고
    • Alterations of central noradregenergic transmission in Ts65Dn mouse, a model for Down syndrome
    • Dierssen M, Vallina IF, Baamonde C, Garcia-Calatayud S, Lumbreras MA, Flôrez J: Alterations of central noradregenergic transmission in Ts65Dn mouse, a model for Down syndrome. Brain Res 1997, 749:238-244.
    • (1997) Brain Res , vol.749 , pp. 238-244
  • 39
    • 0032568615 scopus 로고    scopus 로고
    • Smith DJ, Kilbridge J, Rubin EM, Mobley WC, Epstein CJ, Huang TT: TslCje, a partial trisomy 16 mouse model for Down syndrome, exhibits leaning and behavioral abnormalities
    • Sago H, Carlson EJ. Smith DJ, Kilbridge J, Rubin EM, Mobley WC, Epstein CJ, Huang TT: TslCje, a partial trisomy 16 mouse model for Down syndrome, exhibits leaning and behavioral abnormalities. Proc NatlAcad Sei USA 1998. 95:6256-6261.
    • (1998) Proc NatlAcad Sei USA , vol.95 , pp. 6256-6261
    • Carlson Ej, S.H.1
  • 40
    • 0033985437 scopus 로고    scopus 로고
    • Engineering mouse chromosomes with Cre-LoxP: Range, efficiency, and somatic applications
    • Zheng B, Sage M, Sheppeard EA, Bradley A: Engineering mouse chromosomes with Cre-LoxP: range, efficiency, and somatic applications. Mol Cell Bio/ 2000, 20:648-655.
    • (2000) Mol Cell Bio , vol.20 , pp. 648-655


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.