-
1
-
-
0031418658
-
The carcinogenic potential of the gas phase of environmental tobacco smoke
-
Witschi H., Espiritu I., Maronpot R., Pinkerton K.E., and Jones A.D. The carcinogenic potential of the gas phase of environmental tobacco smoke. Carcinogenesis 18 (1997) 2035-2042
-
(1997)
Carcinogenesis
, vol.18
, pp. 2035-2042
-
-
Witschi, H.1
Espiritu, I.2
Maronpot, R.3
Pinkerton, K.E.4
Jones, A.D.5
-
2
-
-
0034079915
-
Assessment of skin absorption and penetration of JP-8 jet fuel and its components
-
McDougal J.N., Pollard D.L., Weisman W., Garrett C.M., and Miller T.E. Assessment of skin absorption and penetration of JP-8 jet fuel and its components. Toxicol. Sci. 55 (2000) 247-255
-
(2000)
Toxicol. Sci.
, vol.55
, pp. 247-255
-
-
McDougal, J.N.1
Pollard, D.L.2
Weisman, W.3
Garrett, C.M.4
Miller, T.E.5
-
3
-
-
33746667107
-
-
United States Environmental Protection Agency (2000). Health and Environmental Effects Profile for Naphthalene. U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-86/241 (NTIS PB88242383).
-
-
-
-
4
-
-
33746767503
-
-
ATSDR, ToxFAQs™ for naphthalene, 1-methylnaphthalene, and 2-methylnaphthalene, http://www.atsdr.cdc.gov/tfacts67.html (2005).
-
-
-
-
6
-
-
18444380276
-
Severe hemolysis and hyperbilirubinemia due to perinatal naphthalene exposure
-
Kaplan M., and Hammerman C. Severe hemolysis and hyperbilirubinemia due to perinatal naphthalene exposure. J. Perinatol. 25 (2005) 359
-
(2005)
J. Perinatol.
, vol.25
, pp. 359
-
-
Kaplan, M.1
Hammerman, C.2
-
7
-
-
33746677392
-
-
1 mice (inhalation studies). U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, NIH publication 92-3141; http://ntp.niehs.nih.gov/ntp/htdocs/LT_rpts/tr410.pdf.
-
-
-
-
8
-
-
33746705500
-
-
National Toxicology Program (2000). Toxicology and carcinogenesis studies of naphthalene (CAS No. 91-20-3) in F344/N rats (inhalation studies). U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, NIH publication 01-4434; http://ntp.niehs.nih.gov/ntp/htdocs/LT_rpts/tr500.pdf.
-
-
-
-
9
-
-
33746712171
-
-
National Toxicology Program http://ntp.niehs.nih.gov 11th Report on Carcinogens (2005) US Department of Health and Human Services.
-
-
-
-
10
-
-
0036985643
-
-
IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Some traditional herbal medicines, some mycotoxins, naphthalene and styrene, IARC Monogr. Eval. Carcinog. Risks Hum. 82 (2002) 1-556.
-
-
-
-
11
-
-
0030028685
-
Cytotoxicity and mutagenicity of polycyclic aromatic hydrocarbon ortho-quinones produced by dihydrodiol dehydrogenase
-
Flowers-Geary L., Bleczinki W., Harvey R.G., and Penning T.M. Cytotoxicity and mutagenicity of polycyclic aromatic hydrocarbon ortho-quinones produced by dihydrodiol dehydrogenase. Chem. Biol. Interact. 99 (1996) 55-72
-
(1996)
Chem. Biol. Interact.
, vol.99
, pp. 55-72
-
-
Flowers-Geary, L.1
Bleczinki, W.2
Harvey, R.G.3
Penning, T.M.4
-
12
-
-
0029063826
-
Evaluation of the generation of genotoxic and cytotoxic metabolites of benzo[a]pyrene, aflatoxin B1, naphthalene and tamoxifen using human liver microsomes and human lymphocytes
-
Wilson A.S., Tingle M.D., Kelly M.D., and Park B.K. Evaluation of the generation of genotoxic and cytotoxic metabolites of benzo[a]pyrene, aflatoxin B1, naphthalene and tamoxifen using human liver microsomes and human lymphocytes. Hum. Exp. Toxicol. 14 (1995) 507-515
-
(1995)
Hum. Exp. Toxicol.
, vol.14
, pp. 507-515
-
-
Wilson, A.S.1
Tingle, M.D.2
Kelly, M.D.3
Park, B.K.4
-
13
-
-
0032967333
-
Role of murine cytochrome P-450 2F2 in metabolic activation of naphthalene and metabolism of other xenobiotics
-
Shultz M.A., Choudary P.V., and Buckpitt A.R. Role of murine cytochrome P-450 2F2 in metabolic activation of naphthalene and metabolism of other xenobiotics. J. Pharmacol. Exp. Ther. 290 (1999) 281-288
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.290
, pp. 281-288
-
-
Shultz, M.A.1
Choudary, P.V.2
Buckpitt, A.R.3
-
14
-
-
13244258413
-
Bioactivation of the pulmonary toxicants naphthalene and 1-nitronaphthalene by rat CYP2F4
-
Baldwin R.M., Shultz M.A., and Buckpitt A.R. Bioactivation of the pulmonary toxicants naphthalene and 1-nitronaphthalene by rat CYP2F4. J. Pharmacol. Exp. Ther. 312 (2005) 857-865
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.312
, pp. 857-865
-
-
Baldwin, R.M.1
Shultz, M.A.2
Buckpitt, A.R.3
-
15
-
-
0033963899
-
Cytotoxicity of 1,2-epoxynaphthalene is correlated with protein binding and in situ glutathione depletion in cytochrome P4501A1 expressing Sf-21 cells
-
Greene J.F., Zheng J., Grant D.F., and Hammock B.D. Cytotoxicity of 1,2-epoxynaphthalene is correlated with protein binding and in situ glutathione depletion in cytochrome P4501A1 expressing Sf-21 cells. Toxicol. Sci. 53 (2000) 352-360
-
(2000)
Toxicol. Sci.
, vol.53
, pp. 352-360
-
-
Greene, J.F.1
Zheng, J.2
Grant, D.F.3
Hammock, B.D.4
-
16
-
-
29944447220
-
In vitro metabolism of naphthalene by human liver microsomal cytochrome P450 enzymes
-
Cho T.M., Rose R.L., and Hodgson E. In vitro metabolism of naphthalene by human liver microsomal cytochrome P450 enzymes. Drug Metab. Dispos. 34 (2006) 176-183
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 176-183
-
-
Cho, T.M.1
Rose, R.L.2
Hodgson, E.3
-
17
-
-
0031573465
-
Biological oxidations and P450 reactions. Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B1
-
Savas U., Carstens C.P., and Jefcoate C.R. Biological oxidations and P450 reactions. Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B1. Arch. Biochem. Biophys. 347 (1997) 181-192
-
(1997)
Arch. Biochem. Biophys.
, vol.347
, pp. 181-192
-
-
Savas, U.1
Carstens, C.P.2
Jefcoate, C.R.3
-
18
-
-
0038771110
-
Predictive value of comparative molecular field analysis modelling of naphthalene inhibition of human CYP2A6 and mouse CYP2A5 enzymes
-
Asikainen A., Tarhanen J., Poso A., Pasanen M., Alhava E., and Juvonen R.O. Predictive value of comparative molecular field analysis modelling of naphthalene inhibition of human CYP2A6 and mouse CYP2A5 enzymes. Toxicol. In Vitro 17 (2003) 449-455
-
(2003)
Toxicol. In Vitro
, vol.17
, pp. 449-455
-
-
Asikainen, A.1
Tarhanen, J.2
Poso, A.3
Pasanen, M.4
Alhava, E.5
Juvonen, R.O.6
-
19
-
-
0025011015
-
Isozymes of cytochrome P-450 that metabolize naphthalene in liver and lung of untreated mice
-
Nagata K., Martin B.M., Gillette J.R., and Sasame H.A. Isozymes of cytochrome P-450 that metabolize naphthalene in liver and lung of untreated mice. Drug Metab. Disp. 18 (1990) 557-564
-
(1990)
Drug Metab. Disp.
, vol.18
, pp. 557-564
-
-
Nagata, K.1
Martin, B.M.2
Gillette, J.R.3
Sasame, H.A.4
-
20
-
-
0022355540
-
Differential stereoselectivity of cytochromes P-450b and P-450c in the formation of naphthalene and anthracene 1,2-oxides. The role of epoxide hydrolase in determining the enantiomer composition of the 1,2-dihydrodiols formed
-
van Bladeren P.J., Sayer J.M., Ryan D.E., Thomas P.E., Levin W., and Jerina D.M. Differential stereoselectivity of cytochromes P-450b and P-450c in the formation of naphthalene and anthracene 1,2-oxides. The role of epoxide hydrolase in determining the enantiomer composition of the 1,2-dihydrodiols formed. J. Biol. Chem. 260 (1985) 10226-10235
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 10226-10235
-
-
van Bladeren, P.J.1
Sayer, J.M.2
Ryan, D.E.3
Thomas, P.E.4
Levin, W.5
Jerina, D.M.6
-
21
-
-
0030592950
-
-
A.S. Wilson, C.D. Davis, D.P. Williams, A.R. Buckpitt, M. Pirmohamed, B.K. Park, Characterisation of the toxic metabolite(s) of naphthalene, Toxicology 114 (1996) 233-242 (Erratum in: Toxicology 1997 120 (1997) 75).
-
-
-
-
22
-
-
0026348668
-
Mouse pulmonary cytochrome P-450 naphthalene hydroxylase: cDNA cloning, sequence, and expression in Saccharomyces cerevisiae
-
Ritter J.K., Owens I.S., Negishi M., Nagata K., Sheen Y.Y., Gillette J.R., and Sasame H.A. Mouse pulmonary cytochrome P-450 naphthalene hydroxylase: cDNA cloning, sequence, and expression in Saccharomyces cerevisiae. Biochemistry 30 (1991) 11430-11437
-
(1991)
Biochemistry
, vol.30
, pp. 11430-11437
-
-
Ritter, J.K.1
Owens, I.S.2
Negishi, M.3
Nagata, K.4
Sheen, Y.Y.5
Gillette, J.R.6
Sasame, H.A.7
-
23
-
-
0032518169
-
Cloning and expression of CYP2F3, a cytochrome P450 that bioactivates the selective pneumotoxins 3-methylindole and naphthalene
-
Wang H., Lanza D.L., and Yost G.S. Cloning and expression of CYP2F3, a cytochrome P450 that bioactivates the selective pneumotoxins 3-methylindole and naphthalene. Arch. Biochem. Biophys. 349 (1998) 329-340
-
(1998)
Arch. Biochem. Biophys.
, vol.349
, pp. 329-340
-
-
Wang, H.1
Lanza, D.L.2
Yost, G.S.3
-
24
-
-
0032990708
-
Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells
-
Lanza D.L., Code E., Crespi C.L., Gonzalez F.J., and Yost G.S. Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells. Drug Metab. Dispos. 27 (1999) 798-803
-
(1999)
Drug Metab. Dispos.
, vol.27
, pp. 798-803
-
-
Lanza, D.L.1
Code, E.2
Crespi, C.L.3
Gonzalez, F.J.4
Yost, G.S.5
-
25
-
-
0029000839
-
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor
-
Fernandez-Salguero P., Pineau T., Hilbert D.M., McPhail T., Lee S.S., Kimura S., Nebert D.W., Rudikoff S., Ward J.M., and Gonzalez F.J. Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science 268 (1995) 722-726
-
(1995)
Science
, vol.268
, pp. 722-726
-
-
Fernandez-Salguero, P.1
Pineau, T.2
Hilbert, D.M.3
McPhail, T.4
Lee, S.S.5
Kimura, S.6
Nebert, D.W.7
Rudikoff, S.8
Ward, J.M.9
Gonzalez, F.J.10
-
26
-
-
0029867020
-
Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism
-
Liang H.C., Li H., McKinnon R.A., Duffy J.J., Potter S.S., Puga A., and Nebert D.W. Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism. Proc. Natl. Acad. Sci. USA 93 (1996) 1671-1676
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1671-1676
-
-
Liang, H.C.1
Li, H.2
McKinnon, R.A.3
Duffy, J.J.4
Potter, S.S.5
Puga, A.6
Nebert, D.W.7
-
27
-
-
0034614595
-
Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery
-
Dalton T.P., Dieter M.Z., Matlib R.S., Childs N.L., Shertzer H.G., Genter M.B., and Nebert D.W. Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery. Biochem. Biophys. Res. Commun. 267 (2000) 184-189
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.267
, pp. 184-189
-
-
Dalton, T.P.1
Dieter, M.Z.2
Matlib, R.S.3
Childs, N.L.4
Shertzer, H.G.5
Genter, M.B.6
Nebert, D.W.7
-
28
-
-
77957177877
-
Histopathologic examination of the rat nasal cavity
-
Young J.T. Histopathologic examination of the rat nasal cavity. Fundam. Appl. Toxicol. 1 (1981) 309-312
-
(1981)
Fundam. Appl. Toxicol.
, vol.1
, pp. 309-312
-
-
Young, J.T.1
-
29
-
-
8444252098
-
Glutathione depletion is a major determinant of inhaled naphthalene respiratory toxicity and naphthalene metabolism in mice
-
Phimister A.J., Lee M.G., Morin D., Buckpitt A.R., and Plopper C.G. Glutathione depletion is a major determinant of inhaled naphthalene respiratory toxicity and naphthalene metabolism in mice. Toxicol. Sci. 82 (2004) 268-278
-
(2004)
Toxicol. Sci.
, vol.82
, pp. 268-278
-
-
Phimister, A.J.1
Lee, M.G.2
Morin, D.3
Buckpitt, A.R.4
Plopper, C.G.5
-
30
-
-
0031972786
-
Constitutive activation of the aromatic hydrocarbon receptor
-
Chang C.Y., and Puga A. Constitutive activation of the aromatic hydrocarbon receptor. Mol. Cell. Biol. 18 (1998) 525-535
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 525-535
-
-
Chang, C.Y.1
Puga, A.2
-
31
-
-
0033049368
-
Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization
-
Dey A., Jones J.E., and Nebert D.W. Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization. Biochem. Pharmacol. 58 (1999) 525-537
-
(1999)
Biochem. Pharmacol.
, vol.58
, pp. 525-537
-
-
Dey, A.1
Jones, J.E.2
Nebert, D.W.3
-
32
-
-
74049156726
-
Suicide inhibition of CYP2F2, the enzyme responsible for naphthalene (NA) metabolism to a Clara cell toxicant
-
Chang A., Buckpitt A., Plopper C., and Alworth W. Suicide inhibition of CYP2F2, the enzyme responsible for naphthalene (NA) metabolism to a Clara cell toxicant. Toxicologist 30 (1996) 72
-
(1996)
Toxicologist
, vol.30
, pp. 72
-
-
Chang, A.1
Buckpitt, A.2
Plopper, C.3
Alworth, W.4
-
33
-
-
0032527044
-
Mechanism-based inactivation of cytochromes P450 2E1 and 2B1 by 5-phenyl-1-pentyne
-
Roberts E.S., Alworth W.L., and Hollenberg P.F. Mechanism-based inactivation of cytochromes P450 2E1 and 2B1 by 5-phenyl-1-pentyne. Arch. Biochem. Biophys. 354 (1998) 295-302
-
(1998)
Arch. Biochem. Biophys.
, vol.354
, pp. 295-302
-
-
Roberts, E.S.1
Alworth, W.L.2
Hollenberg, P.F.3
-
34
-
-
2342663701
-
Benzene metabolism in human lung cell lines BEAS-2B and A549 and cells overexpressing CYP2F1
-
Sheets P.L., Yost G.S., and Carlson G.P. Benzene metabolism in human lung cell lines BEAS-2B and A549 and cells overexpressing CYP2F1. J. Biochem. Mol. Toxicol. 18 (2004) 92-99
-
(2004)
J. Biochem. Mol. Toxicol.
, vol.18
, pp. 92-99
-
-
Sheets, P.L.1
Yost, G.S.2
Carlson, G.P.3
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