Investigations into the ability of an oblique α-helical template to provide the basis for design of an antimicrobial anionic amphiphilic peptide

FEBS Journal

Volumn 273, Issue 16, 2006, Pages 3792-3803

  Dennison, Sarah R ^a   Morton, Leslie H G ^a   Brandenburg, Klaus ^b   Harris, Frederick ^a   Phoenix, David A ^a  

^a UNIVERSITY OF CENTRAL LANCASHIRE   (United Kingdom)

^b RESEARCH CENTER BORSTEL   (Germany)

Author keywords

helical; Anionic; Antimicrobial; Membrane; Peptide

Indexed keywords

AMINO ACID DERIVATIVE; AMPHOPHILE; GLYCYLGLUTAMYLGLUTAMINYLGLYCYLALANYLLEUCYLALANYLGLUTAMINYLPHENYLALANYL GLYCYLGLUTAMYLTRYPTOPHYLLEUCINE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BACTERIAL MEMBRANE; CELL MEMBRANE FLUIDITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOLYSIS; DRUG DESIGN; DRUG EFFICACY; ENTHALPY; ERYTHROCYTE; ESCHERICHIA COLI; INFRARED SPECTROSCOPY; ISOTHERM; LANGMUIR BLODGETT FILM; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; THERMODYNAMICS; THERMOSTABILITY;

AMINO ACID SEQUENCE; ANIONS; ANTI-INFECTIVE AGENTS; DRUG DESIGN; ESCHERICHIA COLI; LIPID BILAYERS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PROTEIN STRUCTURE, SECONDARY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THERMODYNAMICS; TIME FACTORS;

ESCHERICHIA COLI;

EID: 33746695401     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05387.x     Document Type: Article

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