Chapter 10: The circadian modulation of leptin-controlled bone formation

Progress in Brain Research

Volumn 153, Issue , 2006, Pages 177-188

  Fu, Loning ^a   Patel, Millan S ^a   Karsenty, Gerard ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

bone remodeling; leptin control of bone mass; the molecular clock

Indexed keywords

CRYPTOCHROME; CYCLIN G1; LEPTIN; MYC PROTEIN; CELL CYCLE PROTEIN; NUCLEAR PROTEIN; PER1 PROTEIN, MOUSE; PER2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ADRENERGIC STIMULATION; BONE DEVELOPMENT; BONE MASS; BONE REMODELING; BRAIN LEVEL; CELL COUNT; CELL CYCLE; CELL KINETICS; CELL PROLIFERATION; CIRCADIAN RHYTHM; CORTICAL BONE; DEVELOPMENTAL DISORDER; GENE; GENE EXPRESSION REGULATION; GENE MUTATION; GENE OVEREXPRESSION; IN VIVO STUDY; MOLECULAR CLOCK; NONHUMAN; OSSIFICATION; OSTEOBLAST; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SERUM; SIGNAL TRANSDUCTION; STARVATION; SYMPATHETIC FUNCTION; TARGET VARIABLE; WEIGHT; ANIMAL; BIOLOGICAL MODEL; GENETICS; HUMAN; MOUSE; MOUSE MUTANT; PHYSIOLOGY;

ANIMALS; CELL CYCLE PROTEINS; CIRCADIAN RHYTHM; HUMANS; LEPTIN; MICE; MICE, MUTANT STRAINS; MODELS, BIOLOGICAL; NUCLEAR PROTEINS; OSTEOGENESIS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 33746676358     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(06)53010-9     Document Type: Review

References (25)

1. Chien K.R., and Karsenty G. Longevity and lineages: toward the integrative biology of degenerative diseases in heart, muscle, and bone. Cell 120 (2005) 533-544
2. Ducy P., Amling M., Takeda S., Priemel M., Schilling A.F., Beil F.T., Shen J., Vinson C., Rueger J.M., and Karsenty G. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 100 (2000) 197-207
3. Elefteriou F., Ahn J.D., Takeda S., Starbuck M., Yang X., Liu X., Kondo H., Richards W.G., Bannon T.W., Noda M., et al. Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature 434 (2005) 514-520
4. Elefteriou F., Takeda S., Ebihara K., Magre J., Patano N., Kim C.A., Ogawa Y., Liu X., Ware S.M., Craigen W.J., et al. Serum leptin level is a regulator of bone mass. Proc. Natl. Acad. Sci. USA 101 (2004) 3258-3263
5. Fu L., and Lee C.C. The circadian clock: pacemaker and tumour suppressor. Nat. Rev. Cancer 3 (2003) 350-361
6. Fu L., Pelicano H., Liu J., Huang P., and Lee C. The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo. Cell 111 (2002) 41-50
7. Fu M., Wang C., Li Z., Sakamaki T., and Pestell R.G. Minireview: Cyclin D1: normal and abnormal functions. Endocrinology 145 (2004) 5439-5447
8. Grigoriadis A.E., Wang Z.Q., and Wagner E.F. Fos and bone cell development: lessons from a nuclear oncogene. Trends Genet. 11 (1995) 436-441
9. Gundberg C.M., Markowitz M.E., Mizruchi M., and Rosen J.F. Osteocalcin in human serum: a circadian rhythm. J. Clin. Endocrinol. Metab. 60 (1985) 736-739
10. Jochum W., David J.P., Elliott C., Wutz A., Plenk Jr. H., Matsuo K., and Wagner E.F. Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1. Nat. Med. 6 (2000) 980-984
11. Kalsbeek A., Fliers E., Romijn J.A., La Fleur S.E., Wortel J., Bakker O., Endert E., and Buijs R.M. The suprachiasmatic nucleus generates the diurnal changes in plasma leptin levels. Endocrinology 142 (2001) 2677-2685
12. Kenner L., Hoebertz A., Beil T., Keon N., Karreth F., Eferl R., Scheuch H., Szremska A., Amling M., Schorpp-Kistner M., et al. Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects. J. Cell Biol. 164 (2004) 613-623
13. Matsuo T., Yamaguchi S., Mitsui S., Emi A., Shimoda F., and Okamura H. Control of mechanism of the circadian clock for timing of cell division in vivo. Science 302 (2003) 255-259
14. Perez-Roger I., Kim S.H., Griffiths B., Sewing A., and Land H. Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1). Embo J. 18 (1999) 5310-5320
15. Reppert S.M., and Weaver D.R. Coordination of circadian timing in mammals. Nature 418 (2002) 935-941
16. Resnitzky D., and Reed S.I. Different roles for cyclins D1 and E in regulation of the G1-to-S transition. Mol. Cell Biol. 15 (1995) 3463-3469
17. Riggs B.L., and Melton 3rd. L.J. Involutional osteoporosis. N. Engl. J. Med. 314 (1986) 1676-1686
18. Sabatakos G., Sims N.A., Chen J., Aoki K., Kelz M.B., Amling M., Bouali Y., Mukhopadhyay K., Ford K., Nestler E.J., and Baron R. Overexpression of delta FosB transcription factor(s) increases bone formation and inhibits adipogenesis. Nat. Med. 6 (2000) 985-990
19. Scarpace P.J., and Matheny M. Leptin induction of UCP1 gene expression is dependent on sympathetic innervation. Am. J. Physiol. 275 (1998) E259-E264
20. Simmons D.J., and Nichols Jr. G. Diurnal periodicity in the metabolic activity of bone tissue. Am. J. Physiol. 210 (1966) 411-418
21. Takeda S., Elefteriou F., Levasseur R., Liu X., Zhao L., Parker K.L., Armstrong D., Ducy P., and Karsenty G. Leptin regulates bone formation via the sympathetic nervous system. Cell 111 (2002) 305-317
22. Takeda S., and Karsenty G. Central control of bone formation. J. Bone Mineral Metab. 19 (2001) 195-198
23. Vitaterna M.H., Selby C.P., Todo T., Niwa H., Thompson C., Fruechte E.M., Hitomi K., Thresher R.J., Ishikawa T., Miyazaki J., et al. Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2. Proc. Natl. Acad. Sci. USA 96 (1999) 12114-12119
24. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., and Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature 372 (1994) 425-432
25. Zheng B., Albrecht U., Kaasik K., Sage M., Lu W., Vaishnav S., Li Q., Sun Z.S., Eichele G., Bradley A., and Lee C.C. Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell 105 (2001) 683-694