Effects of the intravenous administration of [Lys7]dermorphin on local cerebral glucose utilization in the rat

European Journal of Pharmacology

Volumn 544, Issue 1-3, 2006, Pages 17-20

  Pontieri, Francesco E ^a   Lattanzi, Roberta ^a   Benincasa, Dario ^a   Cavallari, Michele ^a   Negri, Lucia ^a   Orzi, Francesco ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Lys7 dermorphin; Analgesia; Cerebral metabolism; Deoxyglucose

Indexed keywords

ANALGESIC AGENT; DEOXYGLUCOSE; DERMORPHIN; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BRAIN METABOLISM; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; GLUCOSE BRAIN LEVEL; GLUCOSE UTILIZATION; LIMBIC CORTEX; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SENSORIMOTOR CORTEX;

ANALGESIA; ANIMALS; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; INFUSIONS, INTRAVENOUS; LYSINE; MALE; NEUROTRANSMITTER AGENTS; OPIOID PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU; TELENCEPHALON;

EID: 33746642868     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.06.017     Document Type: Article

References (22)

1. Ableitner A. Brain sites involved in delta-opioid receptor-mediated actions. Eur. J. Pharmacol. 271 (1994) 213-222
2. Beck T., Wenzel J., Kuschinsky K., and Krieglstein J. Morphine-induced alterations of local cerebral glucose utilization in the basal ganglia of rats. Brain Res. 497 (1989) 205-213
3. Broccardo M., Improta G., Negri L., and Melchiorri P. Tolerance and physical dependence induced by dermorphin in rats. Eur. J. Pharmacol. 110 (1985) 55-61
4. Cohen S.R., Kimes A.S., and London E.D. Morphine decreases cerebral glucose utilization in limbic and forebrain regions while pain has no effect. Neuropharmacology 30 (1991) 125-134
5. 14C]deoxyglucose method for use in freely moving rats. Brain Res. 499 (1989) 87-92
6. Della Puppa A., Kimes A.S., and London E.D. Dose-dependent effects of d-N-allylnormetazocine on regional cerebral metabolic rates for glucose. Brain Res. 603 (1993) 38-46
7. Di Chiara G., Bassareo V., Fenu S., De Luca M.A., Spina L., Cadoni C., Acquas E., Carboni E., Valentini V., and Lecca D. Dopamine and drug addiction: the nucleus accumbens shell connection. Neuropharmacology 47 Suppl. 1 (2004) 227-241
8. Eisenberg E., McNicol E.D., and Carr D.B. Efficacy and safety of opioid agonists in the treatment of neuropathic pain of nonmalignant origin: systematic review and meta-analysis of randomized controlled trials. JAMA 293 (2005) 3043-3052
9. Fabian I., and Ableitner A. Brain sites involved in mu-opioid-receptor-mediated actions: a 2-deoxyglucose study. Brain Res. 697 (1995) 205-215
10. Martin T.J., Miller Jr. M., Dworkin S.I., Smith J.E., and Porrino L.J. Alteration of local cerebral glucose utilization following intravenous administration of heroin in Fischer 344 rats. Brain Res. 755 (1997) 313-318
11. Melchiorri P., and Negri L. The dermorphin peptide family. Gen. Pharmacol. 7 (1996) 1099-1107
12. Negri L., Erspamer G.F., Severini C., Potenza R.L., Melchiorri P., and Erspamer V. Dermorphin-related peptides from the skin of Phyllomedusa bicolor and their amidated analogs activate two mu opioid receptor subtypes that modulate antinociception and catalepsy in the rat. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 7203-7207
13. 7]dermorphin, a naturally occurring peptide with high affinity for mu-opioid receptors. Br. J. Pharmacol. 114 (1995) 57-66
14. Orzi F., Passarelli F., La Riccia M., Di Grezia R., and Pontieri F.E. Intravenous morphine increases glucose utilization in the shell of the rat nucleus accumbens. Eur. J. Pharmacol. 302 (1996) 49-51
15. 1 receptor-mediated effect. J. Pharmacol. Exp. Ther. 252 (1990) 235-252
16. Pontieri F.E., Tanda G., and Di Chiara G. Intravenous cocaine, morphine and amphetamine preferentially increase extracellular dopamine in the "shell" as compared to the "core" of the rat nucleus accumbens. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 12304-12308
17. Pontieri F.E., Passarelli F., Calò L., and Caronti B. Functional correlates of nicotine administration: similarity with drugs of abuse. J. Mol. Med. 76 (1998) 193-201
18. Porrino L.J. Functional consequences of acute cocaine treatment depend on route of administration. Psychopharmacology 112 (1993) 343-351
19. Przewlocki R. Opioid abuse and brain gene expression. Eur. J. Pharmacol. 500 (2004) 331-349
20. 14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28 (1977) 897-916
21. Suzuki T., Oshimi M., and Hanano M. Differential effects of buprenorphine and pentazocine on the regional cerebral metabolic rate for glucose in the conscious rat. Biol. Pharm. Bull. 20 (1997) 997-1001
22. 1 opioid receptor mechanism. Science 276 (1997) 2048-2050