Intravenous morphine increases glucose utilization in the shell of the rat nucleus accumbens

European Journal of Pharmacology

Volumn 302, Issue 1-3, 1996, Pages 49-51

  Orzi, Francesco ^b   Passarelli, Francesca ^a   La Riccia, Maurizio ^a   Di Grezia, Renato ^b   Pontieri, Francesco E ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS NEUROMED   (Italy)

Author keywords

Deoxyglucose; Drug abuse; Morphine; Nucleus accumbens; Shell

Indexed keywords

MORPHINE SULFATE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN MAPPING; BRAIN METABOLISM; CONTROLLED STUDY; DRUG ABUSE; GLUCOSE UTILIZATION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT;

EID: 0030008749     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00128-8     Document Type: Article

References (15)

1. Alheid, G.F. and L. Heimer, 1988, New perspective in basal forebrain organization of special relevance for neuropsychiatric disorders: the striatopallidal, amygdaloid and corticopetal components of substantia innominata, Neuroscience 27, 1.
2. Beck, T., J. Wenzel, K. Kuschinski and J. Krieglstein, 1989, Morphine-induced alterations of local cerebral glucose utilization in the basal ganglia of rats, Brain Res. 497, 205.
3. 14C]-deoxyglucose method for use in freely moving rats, Brain Res. 499, 87.
4. Di Chiara, G., 1995, The role of dopamine in drug abuse viewed from the perspective of its role in motivation, Drug Alcohol Depend. 38, 95.
5. Di Chiara, G. and R.A. North, 1992, Neurobiology of opiate abuse, Trends Pharmacol. Sci. 13, 185.
6. Heimer, L., J. DeOlmos, G.F. Alheid and L. Zaborski, 1991, 'Perestroika' in the basal forebrain: opening the border between neurology and psychiatry, Prog. Brain Res. 87, 109.
7. Levy, R.M., H.L. Fields, M.P. Stryke and M.M. Heinricher, 1986, The effects of analgesic doses of morphine on regional cerebral glucose metabolism in pain-related structures, Brain Res. 368, 170.
8. London, E., R. Fanelli, M. Szikszay and D. Jasinski, 1986, Effects of opioid analgesics on local cerebral glucose utilization, NIDA Res. Monogr. 75, 379.
9. Pontieri, F.E., V. Colangelo, M. La Riccia, C. Pozzilli, F. Passarelli and F. Orzi, 1994, Psychostimulant drugs increase glucose utilization in the shell of the rat nucleus accumbens, NeuroReport 5, 2561.
10. Pontieri, F.E., G. Tanda and G. Di Chiara, 1995, Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the 'shell' as compared to the 'core' of the rat nucleus accumbens, Proc. Natl. Acad. Sci. USA 92, 12304.
11. Porrino, L.J., 1993, Functional consequences of acute cocaine treatment depend on route of administration, Psychopharmacology 112, 343.
12. Porrino, L.J., G. Lucignani, D. Dow-Edwards and L. Sokoloff, 1984, Dose-dependent effect of acute amphetamine administration on functional brain metabolism in rats, Brain Res. 307, 311.
13. Porrino, L.J., F.R. Domer, A.M. Crane and L. Sokoloff, 1988, Selective alterations in cerebral metabolism within the mesocorticolimbic dopaminergic system produced by acute cocaine administration in rats, Neuropsychopharmacology 1, 109.
14. 14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28, 897.
15. Weeks, J.R. and R.J. Collins, 1976, Changes in morphine self-administration in rats induced by prostaglandin E and naloxone, Prostaglandins 12, 11.