Intracellular-activated Notch1 can reactivate Kaposi's sarcoma-associated herpesvirus from latency

Virology

Volumn 351, Issue 2, 2006, Pages 393-403

  Lan, Ke ^a   Murakami, Masanao ^a   Choudhuri, Tathagata ^a   Kuppers, Daniel A ^a   Robertson, Erle S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

KSHV; LANA; Notch1

Indexed keywords

NOTCH1 RECEPTOR;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC CODE; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; IMMUNE SYSTEM; LYMPHOMA CELL; PLEURA EFFUSION; PRIORITY JOURNAL; VIRUS REPLICATION;

B-LYMPHOCYTES; CELL LINE; GENE EXPRESSION REGULATION, VIRAL; HERPESVIRUS 8, HUMAN; HUMANS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECEPTOR, NOTCH1; SARCOMA, KAPOSI; TRANS-ACTIVATION (GENETICS); VIRUS ACTIVATION; VIRUS LATENCY;

HUMAN HERPESVIRUS 8;

EID: 33746549149     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2006.03.047     Document Type: Article

References (49)

1. Aster J.C., Robertson E.S., Hasserjian R.P., Turner J.R., Kieff E., and Sklar J. Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jkappa or nuclear localization sequences retain the ability to associate with RBP-Jkappa and activate transcription. J. Biol. Chem. 272 17 (1997) 11336-11343
2. Aster J.C., Xu L., Karnell F.G., Patriub V., Pui J.C., and Pear W.S. Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1. Mol. Cell. Biol. 20 20 (2000) 7505-7515
3. Boshoff C., and Weiss R.A. Epidemiology and pathogenesis of Kaposi's sarcoma-associated herpesvirus. Philos. Trans. R. Soc. London, Ser. B Biol. Sci. 356 1408 (2001) 517-534
4. Brennan K., and Gardner P. Notching up another pathway. Bioessays 24 5 (2002) 405-410
5. Brown H.J., Song M.J., Deng H., Wu T.T., Cheng G., and Sun R. NF-kappaB inhibits gammaherpesvirus lytic replication. J. Virol. 77 15 (2003) 8532-8540
6. Cannon J.S., Ciufo D., Hawkins A.L., Griffin C.A., Borowitz M.J., Hayward G.S., and Ambinder R.F. A new primary effusion lymphoma-derived cell line yields a highly infectious Kaposi's sarcoma herpesvirus-containing supernatant. J. Virol. 74 21 (2000) 10187-10193
7. Cesarman E. The role of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in lymphoproliferative diseases. Recent Results Cancer Res. 159 (2002) 27-37
8. Cesarman E., Chang Y., Moore P.S., Said J.W., and Knowles D.M. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N. Engl. J. Med. 332 18 (1995) 1186-1191
9. Cesarman E., Nador R.G., Aozasa K., Delsol G., Said J.W., and Knowles D.M. Kaposi's sarcoma-associated herpesvirus in non-AIDS related lymphomas occurring in body cavities. Am. J. Pathol. 149 1 (1996) 53-57
10. Cesarman E., Nador R.G., Bai F., Bohenzky R.A., Russo J.J., Moore P.S., Chang Y., and Knowles D.M. Kaposi's sarcoma-associated herpesvirus contains G protein-coupled receptor and cyclin D homologs which are expressed in Kaposi's sarcoma and malignant lymphoma. J. Virol. 70 11 (1996) 8218-8223
11. Chang Y., Cesarman E., Pessin M.S., Lee F., Culpepper J., Knowles D.M., and Moore P.S. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266 5192 (1994) 1865-1869
12. Chang H., Dittmer D.P., Chul S.Y., Hong Y., and Jung J.U. Role of Notch signal transduction in Kaposi's sarcoma-associated herpesvirus gene expression. J. Virol. 79 22 (2005) 14371-14382
13. Curry C.L., Reed L.L., Golde T.E., Miele L., Nickoloff B.J., and Foreman K.E. Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells. Oncogene 24 42 (2005) 6333-6344
14. Deng H., Young A., and Sun R. Auto-activation of the rta gene of human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus. J. Gen. Virol. 81 Pt. 12 (2000) 3043-3048
15. Ellisen L.W., Bird J., West D.C., Soreng A.L., Reynolds T.C., Smith S.D., and Sklar J. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66 4 (1991) 649-661
16. Friborg Jr. J., Kong W., Hottiger M.O., and Nabel G.J. p53 inhibition by the LANA protein of KSHV protects against cell death. Nature 402 6764 (1999) 889-894
17. Furukawa T., Maruyama S., Kawaichi M., and Honjo T. The Drosophila homolog of the immunoglobulin recombination signal-binding protein regulates peripheral nervous system development. Cell 69 7 (1992) 1191-1197
18. Guasparri I., Keller S.A., and Cesarman E. KSHV vFLIP is essential for the survival of infected lymphoma cells. J. Exp. Med. 199 7 (2004) 993-1003
19. Haque M., Davis D.A., Wang V., Widmer I., and Yarchoan R. Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) contains hypoxia response elements: relevance to lytic induction by hypoxia. J. Virol. 77 12 (2003) 6761-6768
20. Hsieh J.J., and Hayward S.D. Masking of the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2. Science 268 5210 (1995) 560-563
21. Lan K., Kuppers D.A., Verma S.C., and Robertson E.S. Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta: a potential mechanism for virus-mediated control of latency. J. Virol. 78 12 (2004) 6585-6594
22. Lan K., Kuppers D.A., and Robertson E.S. Kaposi's sarcoma-associated herpesvirus reactivation is regulated by interaction of latency-associated nuclear antigen with recombination signal sequence-binding protein Jkappa, the major downstream effector of the Notch signaling pathway. J. Virol. 79 6 (2005) 3468-3478
23. Lan K., Kuppers D.A., Verma S.C., Sharma N., Murakami M., and Robertson E.S. Induction of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen by the lytic transactivator RTA: a novel mechanism for establishment of latency. J. Virol. 79 12 (2005) 7453-7465
24. Liang Y., and Ganem D. Lytic but not latent infection by Kaposi's sarcoma-associated herpesvirus requires host CSL protein, the mediator of Notch signaling. Proc. Natl. Acad. Sci. U.S.A. 100 14 (2003) 8490-8495
25. Liang Y., Chang J., Lynch S.J., Lukac D.M., and Ganem D. The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway. Genes Dev. 16 15 (2002) 1977-1989
26. Lu F.M., and Lux S.E. Constitutively active human Notch1 binds to the transcription factor CBF1 and stimulates transcription through a promoter containing a CBF1-responsive element. Proc. Natl. Acad. Sci. U.S.A. 93 11 (1996) 5663-5667
27. Lukac D.M., Renne R., Kirshner J.R., and Ganem D. Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein. Virology 252 2 (1998) 304-312
28. Lukac D.M., Kirshner J.R., and Ganem D. Transcriptional activation by the product of open reading frame 50 of Kaposi's sarcoma-associated herpesvirus is required for lytic viral reactivation in B cells. J. Virol. 73 11 (1999) 9348-9361
29. Miller G., Heston L., Grogan E., Gradoville L., Rigsby M., Sun R., Shedd D., Kushnaryov V.M., Grossberg S., and Chang Y. Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein-Barr virus in dually infected body cavity lymphoma cells. J. Virol. 71 1 (1997) 314-324
30. Nakamura H., Lu M., Gwack Y., Souvlis J., Zeichner S.L., and Jung J.U. Global changes in Kaposi's sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivator. J. Virol. 77 7 (2003) 4205-4220
31. Nam Y., Aster J.C., and Blacklow S.C. Notch signaling as a therapeutic target. Curr. Opin. Chem. Biol. 6 4 (2002) 501-509
32. Neipel F., and Fleckenstein B. The role of HHV-8 in Kaposi's sarcoma. Semin. Cancer Biol. 9 3 (1999) 151-164
33. Radtke F., Wilson A., Mancini S.J., and MacDonald H.R. Notch regulation of lymphocyte development and function. Nat. Immunol. 5 3 (2004) 247-253
34. Renne R., Zhong W., Herndier B., McGrath M., Abbey N., Kedes D., and Ganem D. Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat. Med. 2 3 (1996) 342-346
35. Renne R., Blackbourn D., Whitby D., Levy J., and Ganem D. Limited transmission of Kaposi's sarcoma-associated herpesvirus in cultured cells. J. Virol. 72 6 (1998) 5182-5188
36. Russo J.J., Bohenzky R.A., Chien M.C., Chen J., Yan M., Maddalena D., Parry J.P., Peruzzi D., Edelman I.S., Chang Y., and Moore P.S. Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc. Natl. Acad. Sci. U.S.A. 93 25 (1996) 14862-14867
37. Sarid R., Flore O., Bohenzky R.A., Chang Y., and Moore P.S. Transcription mapping of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) genome in a body cavity-based lymphoma cell line (BC-1). J. Virol. 72 2 (1998) 1005-1012
38. Sarid R., Olsen S.J., and Moore P.S. Kaposi's sarcoma-associated herpesvirus: epidemiology, virology, and molecular biology. Adv. Virus Res. 52 (1999) 139-232
39. Sarid R., Klepfish A., and Schattner A. Virology, pathogenetic mechanisms, and associated diseases of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8). Mayo Clin. Proc. 77 9 (2002) 941-949
40. Schroeter E.H., Kisslinger J.A., and Kopan R. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393 6683 (1998) 382-386
41. Schulz T.F., and Moore P.S. Kaposi's sarcoma-associated herpesvirus: a new human tumor virus, but how?. Trends Microbiol. 7 5 (1999) 196-200
42. Schweisguth F., and Posakony J.W. Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates. Cell 69 7 (1992) 1199-1212
43. Soulier J., Grollet L., Oksenhendler E., Cacoub P., Cazals-Hatem D., Babinet P., d'Agay M.F., Clauvel J.P., Raphael M., Degos L., et al. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood 86 4 (1995) 1276-1280
44. Sun R., Lin S.F., Gradoville L., Yuan Y., Zhu F., and Miller G. A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus. Proc. Natl. Acad. Sci. U.S.A. 95 18 (1998) 10866-10871
45. Sun R., Lin S.F., Staskus K., Gradoville L., Grogan E., Haase A., and Miller G. Kinetics of Kaposi's sarcoma-associated herpesvirus gene expression. J. Virol. 73 3 (1999) 2232-2242
46. Taylor J.L., Bennett H.N., Snyder B.A., Moore P.S., and Chang Y. Transcriptional analysis of latent and inducible Kaposi's sarcoma-associated herpesvirus transcripts in the K4 to K7 region. J. Virol. 79 24 (2005) 15099-15106
47. West J.T., and Wood C. The role of Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 regulator of transcription activation (RTA) in control of gene expression. Oncogene 22 33 (2003) 5150-5163
48. Wu L., and Griffin J.D. Modulation of Notch signaling by mastermind-like (MAML) transcriptional co-activators and their involvement in tumorigenesis. Semin. Cancer Biol. 14 5 (2004) 348-356
49. Zhou F.C., Zhang Y.J., Deng J.H., Wang X.P., Pan H.Y., Hettler E., and Gao S.J. Efficient infection by a recombinant Kaposi's sarcoma-associated herpesvirus cloned in a bacterial artificial chromosome: application for genetic analysis. J. Virol. 76 12 (2002) 6185-6196