Design of cyclic peptides with agonist activity at melanocortin receptor-4

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 14, 2006, Pages 3723-3726

  Odagami, Takenao ^a   Tsuda, Yuko ^b   Kogami, Yuji ^a   Kouji, Hiroyuki ^a   Okada, Yoshio ^b  

^a ASAHI KASEI PHARMA CORPORATION   (Japan)

^b KOBE GAKUIN UNIVERSITY   (Japan)

Author keywords

Agonist; Cyclic peptide; hMC 4R

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; CYCLO(HISTIDYL DEXTRO PHENYLALANYLARGINYLTRYPTOPHYL 7 AMINOHEPTANOIC ACID); CYCLO(HISTIDYL DEXTRO PHENYLALANYLARGINYLTRYPTOPHYL 8 AMINOHEXANOIC ACID); CYCLO(HISTIDYL DEXTRO PHENYLALANYLARGINYLTRYPTOPHYL 8 AMINOOCTANOIC ACID); CYCLO(HISTIDYL DEXTRO PHENYLALANYLARGINYLTRYPTOPHYL BETA ALANINE); CYCLO(HISTIDYLPHENYLALANYLARGINYLTRYPTOPHYL 7 AMINOHEPTANOIC ACID); MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 4 RECEPTOR AGONIST; OMEGA AMINO ACID; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

ALPHA-MSH; AMINO ACID SEQUENCE; CIRCULAR DICHROISM; DRUG DESIGN; HUMANS; LACTAMS; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; PROTEIN BINDING; RECEPTOR, MELANOCORTIN, TYPE 1; RECEPTOR, MELANOCORTIN, TYPE 4; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33746496742     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.04.050     Document Type: Article

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