c-Fos Is a Critical Mediator of Inflammatory-Mediated Repression of the Apical Sodium-Dependent Bile Acid Transporter

Gastroenterology

Volumn 131, Issue 2, 2006, Pages 554-567

  Neimark, Ezequiel ^a   Chen, Frank ^a   Li, Xiaoping ^a   Magid, Margret S ^a   Alasio, Teresa M ^a   Frankenberg, Tamara ^a   Sinha, Jyoti ^a   Dawson, Paul A ^b   Shneider, Benjamin L ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; APICAL SODIUM DEPENDENT BILE ACID TRANSPORTER; BILE ACID; CARRIER PROTEIN; CYTOKINE; INDOMETACIN; INTERLEUKIN 1BETA; MESSENGER RNA; PROTEIN C FOS; PROTEIN C JUN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; ILEITIS; ILEUM MUCOSA; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RAT; TRANSGENIC MOUSE; UPREGULATION; WILD TYPE;

EID: 33746477130     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2006.05.002     Document Type: Article

References (55)

1. Hofmann A. The enterohepatic circulation of bile acids in health and disease. In: Sleisenger M.H., and Fordtran J.S. (Eds). Gastrointestinal disease pathophysiology/diagnosis/management. 5th ed. Volume 1 (1993), Saunders, Philadelphia, PA 127-149
2. Wong M.H., Oelkers P., Craddock A.L., and Dawson P.A. Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter. J Biol Chem 269 (1994) 1340-1347
3. Shneider B.L., Dawson P.A., Christie D.M., Hardikar W., Wong M.H., and Suchy F.J. Cloning and molecular characterization of the ontogeny of a rat ileal sodium-dependent bile acid transporter. J Clin Invest 95 (1995) 745-754
4. Christie D.M., Dawson P.A., Thevananther S., and Shneider B.L. Comparative analysis of the ontogeny of a sodium-dependent bile acid transporter in rat kidney and ileum. Am J Physiol 271 (1996) G377-G385
5. +-dependent bile acid transporter in large but not small rat cholangiocytes. Gastroenterology 113 (1997) 1734-1740
6. Lazaridis K., Pham L., Tietz, Marinelli R., deGroen P., Levine S., Dawson P., and LaRusso N. Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter. J Clin Invest 100 (1997) 2714-2721
7. Chignard N., Mergey M., Veissiere D., Parc R., Capeau J., Poupon R., Paul A., and Housset C. Bile acid transport and regulating functions in the human biliary epithelium. Hepatology 33 (2001) 496-503
8. Chen F., Ananthanarayanan M., Emre S., Neimark E., Bull L.N., Knisely A.S., Strautnieks S.S., Thompson R.J., Magid M.S., Gordon R., Balasubramanian N., Suchy F.J., and Shneider B.L. Progressive familial intrahepatic cholestasis, type 1, is associated with decreased farnesoid X receptor activity. Gastroenterology 126 (2004) 756-764
9. Heubi J.E., Balistreri W.F., Fondacaro J.D., Partin J.C., and Schubert W.K. Primary bile acid malabsorption. defective in vitro ileal active bile acid transport. Gastroenterology 83 (1982) 804-811
10. Oelkers P., Kirby L.C., Heubi J.E., and Dawson P.A. Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2). J Clin Invest 99 (1997) 1880-1887
11. Tougaard L., Giese B., Pedersen B., and Binder V. Bile acid metabolism in patients with Crohn's disease in terminal ileum. Scand. J. Gastroenterol 21 (1986) 627-633
12. 12 metabolism in ileal Crohn's disease. Am J Clin Pathol 73 (1980) 69-74
13. Krag B., and Krag B. Regional ileitis (Crohn's disease): I. Kinetics of bile acid absorption in the perfused ileum. Scand J Gastroenterol 11 (1976) 481-486
14. Balistreri W.F., Suchy F.J., and Heubi J.E. Serum bile acid response to a test meal stimulus. a sensitive test of ileal function. J Pediatr 96 (1980) 582-589
15. Heuman R., Sjodahl R., Tobiasson P., and Tagesson C. Postprandial serum bile acids in resected and non-resected patients with Crohn's disease. Scand J Gastroenterol 17 (1982) 137-140
16. 75Se)-labelled bile acid for the investigation of terminal ileal function. Hepatogastroenterology 31 (1984) 187-191
17. Lanzini A., De Tavonatti M.G., Panarotto B., Scalia S., Mora A., Benini F., Baisini O., and Lanzarotto F. Intestinal absorption of the bile acid analogue 75Se-homocholic acid-taurine is increased in primary biliary cirrhosis, and reverts to normal during ursodeoxycholic acid administration. Gut 52 (2003) 1371-1375
18. Jung D., Fantin A.C., Scheurer U., Fried M., and Kullak-Ublick G.A. Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor. Gut 53 (2004) 78-84
19. +-bile acid cotransport during chronic ileal inflammation in rabbits. Am J Physiol 275 (1998) G1259-G1265
20. Stelzner M., Somasundaram S., and Khakberdiev T. Systemic effects of acute terminal ileitis on uninflamed gut aggravate bile acid malabsorption. J Surg Res 99 (2001) 359-364
21. Groβ V., Andus T., Leser H., Roth M., and Scholmerich J. Inflammatory mediators in chronic inflammatory bowel diseases. Klin Wochenschr 69 (1991) 981-987
22. Green R.M., Beier D., and Gollan J.L. Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents. Gastroenterology 111 (1996) 193-198
23. Trauner M., Arrese M., Lee H., Boyer J.L., and Karpen S.J. Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors. J Clin Invest 101 (1998) 2092-2100
24. Hartmann G., Cheung A.K., and Piquette-Miller M. Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia. J Pharmacol Exp Ther 303 (2002) 273-281
25. Denson L.A., Auld K.L., Schiek D.S., McClure M.H., Mangelsdorf D.J., and Karpen S.J. Interleukin-1beta suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation. J Biol Chem 275 (2000) 8835-8843
26. Chen F., Ma L., Al-Ansari N., and Shneider B. The role of AP-1 in the transcriptional regulation of the rat apical sodium-dependent bile acid transporter. J Biol Chem 276 (2001) 38703-38714
27. Koj A. Initiation of acute phase response and synthesis of cytokines. Biochim Biophys Acta 1317 (1996) 84-94
28. Chen F., Ma L., Sartor R.B., Li F., Xiong H., Sun A.Q., and Shneider B. Inflammatory-mediated repression of the rat ileal sodium-dependent bile acid transporter by c-fos nuclear translocation. Gastroenterology 123 (2002) 2005-2016
29. Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162 (1987) 156-159
30. Craddock A., Love M., Daniel R., Kirby L., Walters H., Wong M., and Dawson P. Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter. Am J Physiol 274 (1998) G157-G169
31. Trejo J., and Brown J.H. c-fos and c-jun are induced by muscarinic receptor activation of protein kinase C but are differentially regulated by intracellular calcium. J Biol Chem 266 (1991) 7876-7882
32. Zhu C., Gagnidze K., Gemberling J., and Plevy S. Characterization of an activation protein-1 binding site in the murine interleukin-12 p40 promoter. demonstration of novel functional elements by a reductionist approach. J Biol Chem 276 (2001) 18519-18528
33. Dawson P.A., Hubbert M., Haywood J., Craddock A.L., Zerangue N., Christian W.V., and Ballatori N. The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter. J Biol Chem 280 (2005) 6960-6968
34. Gray P., Glaister D., Chen E., Goeddel D., and Pennica D. Two interleukin 1 genes in the mouse. cloning and expression of the cDNA for murine interleukin 1 beta. J Immunol 137 (1986) 3644-3648
35. Barbu V., and Dautry F. Northern blot normalization with a 28S rRNA oligonucleotide probe. Nucleic Acids Res 17 (1989) 7115
36. Neimark E., Chen F., Li X., and Shneider B.L. Bile acid-induced negative feedback regulation of the human ileal bile acid transporter. Hepatology 40 (2004) 149-156
37. Chen F., Ma L., Dawson P., Sinal C., Sehayek E., Gonzalez F., Breslow J., Ananthanarayanan M., and Shneider B. Liver receptor homologue-1 mediated species- and cell line-specific bile acid dependent negative feedback regulation of the apical sodium-dependent bile acid transporter. J Biol Chem 278 (2003) 19909-19916
38. Brown P., Kim S., Wise S., Sabichi A., and Birrer M. Dominant-negative mutants of cjun inhibit AP-1 activity through multiple mechanisms and with different potencies. Cell Growth Differ 7 (1996) 1013-1021
39. Olive M., Krylov D., Echlin D., Gardner K., Taparowsky E., and Vinson C. A dominant negative to activation protein-1 that abolishes DNA binding and inhibits oncogenesis. J Biol Chem 272 (1997) 18586-18594
40. Chen F.Y., Harris L.C., Remack J.S., and Brent T.P. Cytoplasmic sequestration of an O6-methylguanine-DNA methyltransferase enhancer binding protein in DNA repair-deficient human cells. Proc Natl Acad Sci U S A 94 (1997) 4348-4353
41. Chen F.Y., Amara F.M., and Wright J.A. Mammalian ribonucleotide reductase R1 mRNA stability under normal and phorbol ester stimulating conditions. involvement of a cis-trans interaction at the 3' untranslated region. EMBO J 12 (1993) 3977-3986
42. Selden R., Howie K., Rowe M., Goodman H., and Moore D. Human growth hormone as a reporter gene in regulation studies employing transient gene expression. Mol Cell Biol 6 (1986) 3173-3179
43. Johnson R., Spiegelman B., and Papaioannou V. Pleitropic effects of a null mutation in the c-fos proto-oncogene. Cell 71 (1992) 577-586
44. Dawson P.A., Haywood J., Craddock A.L., Wilson M., Tietjen M., Kluckman K., Maeda N., and Parks J.S. Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice. J Biol Chem 278 (2003) 33920-33927
45. Kajiura K., Ohkusa T., and Okayasu I. Relationship between fecal bile acids and the occurrence of colorectal neoplasia in experimental murine ulcerative colitis. Digestion 59 (1998) 69-72
46. Gaston K., and Jayaraman P.S. Transcriptional repression in eukaryotes. repressors and repression mechanisms. Cell Mol Life Sci 60 (2003) 721-741
47. Miotto B., Sagnier T., Berenger H., Bohmann D., Pradel J., Graba Y., and Chameau H. HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis. Genes Dev 20 (2006) 101-112
48. Kordula T., Bugno M., Rudel R., and Travis J. Mechanism of interleukin-1- and tumor necrosis factor alpha-dependent regulation of the alpha 1-antichymotrypsin gene in human astrocytes. J Neurosci 20 (2000) 7510-7516
49. Daury L., Busson M., Tourkine N., Casas F., Cassar-Malek I., Wrutniak-Cabello C., Castellazzi M., and Cabello G. Opposing functions of ATF2 and fos-like transcription factors in c-jun-mediated myogenin expression and terminal differentiation of avian myoblasts. Oncogene 20 (2001) 7998-8008
50. Halpern M.D., Holubec H., Saunders T.A., Dvorak K., Clark J.A., Doelle S.M., Ballatori N., and Dvorak B. Bile acids induce ileal damage during experimental necrotizing enterocolitis. Gastroenterology 130 (2006) 359-372
51. Siewertsen M.A., Barker D.F., and Cox D.W. Two polymorphisms of the FOS oncogene. Nucleic Acids Res 18 (1990) 6174
52. Cruts M., Backhovens H., Martin J.J., and van Broeckhoven C. Genetic analysis of the cellular oncogene fos in patients with chromosome 14 encoded Alzheimer's disease. Neurosci Lett 174 (1994) 97-100
53. Kamino K., Miki T., and Ogihara T. Identification of a single base polymorphism in intron 2 of the c-fos gene and its detection by mismatched PCR-RFLP. Jpn J Hum Genet 39 (1994) 439-440
54. Dai X.Y., Hattori M., Yoshizawa J., Matsuda H., Arai H., Akizuki S., and Nanko S. No association between c-fos gene polymorphisms and sporadic Alzheimer's disease. Psychiatr Clin Neurosci 50 (1996) 331-333
55. Umino Y., Hohjoh H., and Tokunaga K. Novel single nucleotide polymorphisms (SNPs) at positions 497 (T/G) and 829 (T/C) in the human c-FOS gene and haplotype association. Hum Mutat 16 (2000) 279