Combination of time-dependent and pH-dependent polymethacrylates as a single coating formulation for colonic delivery of indomethacin pellets

International Journal of Pharmaceutics

Volumn 320, Issue 1-2, 2006, Pages 137-142

  Akhgari, A ^a   Sadeghi, F ^a   Garekani, H Afrasiabi ^a  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Colonic drug delivery; Eudragit; Indomethacin; pH dependent; Sustained release

Indexed keywords

EUDRAGIT; EUDRAGIT RS; INDOMETACIN; POLY(METHYL METHACRYLATE); POLYMER;

ACIDITY; ARTICLE; COLON; CONTROLLED DRUG RELEASE; DISSOLUTION; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG FORMULATION; DRUG PELLET; DRUG SCREENING; DRUG SOLUBILITY; FACTORIAL DESIGN; IN VITRO STUDY; PH MEASUREMENT; PRIORITY JOURNAL; REPRODUCIBILITY; STATISTICAL ANALYSIS; TIMED DRUG RELEASE;

ACRYLIC RESINS; ANALYSIS OF VARIANCE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEMISTRY, PHARMACEUTICAL; COLON; EVALUATION STUDIES; EVALUATION STUDIES AS TOPIC; HYDROGEN-ION CONCENTRATION; INDOMETHACIN; INTESTINAL ABSORPTION; MODELS, STATISTICAL; POLYMETHACRYLIC ACIDS; REGRESSION ANALYSIS; SOLUBILITY; TABLETS, ENTERIC-COATED; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS;

EID: 33746456338     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.05.011     Document Type: Article

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