In vitro proliferation of axotomized rat facial nucleus-derived activated microglia in an autocrine fashion

Journal of Neuroscience Research

Volumn 84, Issue 2, 2006, Pages 348-359

  Nakajima, Kazuyuki ^a,b   Graeber, Manuel B ^c   Sonoda, Maya ^a   Tohyama, Yoko ^a   Kohsaka, Shinichi ^b   Kurihara, Tadashi ^a  

^a SOKA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Axotomy; Colony stimulating factors; Facial nerve; Microglia; Proliferation

Indexed keywords

BROXURIDINE; COLONY STIMULATING FACTOR; COLONY STIMULATING FACTOR 1; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MITOGENIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL CYCLE S PHASE; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; FACIAL NERVE; FACIAL NERVE NUCLEUS; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MICROGLIA; NERVE TRANSECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; AUTOCRINE COMMUNICATION; AXOTOMY; BRAIN STEM; CELL PROLIFERATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FACIAL NERVE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MACROPHAGE COLONY-STIMULATING FACTOR; MALE; MICROGLIA; RATS; RATS, WISTAR; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; RECEPTORS, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 33746396616     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20882     Document Type: Article

References (53)

1. Banati RB, Gehrmann J, Schubert P, Kreutzberg GW. 1993. Cytotoxicity of microglia. Glia 7:111-118.
2. Becher B, Antel JP. 1996. Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia. Glia 18:1-10.
3. Chomczynski P, Sacchi N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
4. De Groot CJ, Montagne L, Janssen I, Ravid R, Van Der Valk P, Veerhuis R. 2000. Isolation and characterization of adult microglial cells and oligodendrocytes derived from postmortem human brain tissue. Brain Res Protoc 5:85-94.
5. Ganter S, Northoff H, Mannel D, Gebicke-Harter PJ. 1992. Growth control of cultured microglia. J Neurosci Res 33:218-230.
6. Gebicke-Haerter PJ, Bauer J, Schobert A, Northoff H. 1989. Lipopolysaccharide-free conditions in primary astrocyte cultures allow growth and isolation of microglial cells. J Neurosci 9:183-194.
7. Giulian D, Baker TJ. 1986. Characterization of ameboid microglia isolated from developing mammalian brain. J Neurosci 6:2163-2178.
8. Giulian D, Ingeman JE. 1988. Colony-stimulating factors as promoters of ameboid microglia. J Neurosci 8:4707-4717.
9. Gottschall PE, Yu X, Bing B. 1995. Increased production of gelatinase B (matrix metalloproteinase-9) and interleukin-6 by activated rat microglia in culture. J Neurosci Res 42:335-342.
10. Graeber MB, Kreutzberg GW. 1986. Astrocytes increase in glial fibrillary acidic protein during retrograde changes of facial motor neurons. J Neurocytol 15:363-373.
11. Graeber MB, Streit WJ, Kreutzberg GW. 1988a. The microglial cytoskeleton: vimentin is localized within activated cells in situ. J Neurocytol 17:573-580.
12. Graeber MB, Streit WJ, Kreutzberg GW. 1988b. Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells. J Neurosci Res 21:18-24.
13. Graeber MB, Streit WJ, Kreutzberg GW. 1989. Formation of microglia-derived brain macrophages is blocked by adriamycin. Acta Neuropathol 78:348-358.
14. Graeber MB, Lopez-Redondo F, Ikoma E, Ishikawa M, Imai Y, Nakajima K, Kreutzberg GW, Kohsaka S. 1998. The microglia/macrophage response in the neonatal rat facial nucleus following axotomy. Brain Res 813:241-253.
15. Guillemin G, Boussin FD, Croitoru J, Franck-Duchenne M, Le Grand R, Lazarini F, Dormont D. 1997. Obtention and characterization of primary astrocyte and microglial cultures from adult monkey brains. J Neurosci Res 49:576-591.
16. Hauer NP, Jarhult JD, Nitsch R. 1996. Resting microglial cells in vitro: analysis of morphology and adhesion molecule expression in organo-typic hippocampal slice cultures. Glia 18:319-331.
17. Hayes GM, Woodroofe MN, Cuzner ML. 1988. Characterisation of microglia isolated from adult human and rat brain. J Neuroimmunol 19:177-189.
18. Imai Y, Kohsaka S. 2002. Intracellular signaling in M-CSF-induced microglia activation: role of Ibal. Glia 40:164-174.
19. Imai Y, Ibata I, Ito D, Ohsawa K, Kohsaka S. 1996. A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. Biochem Biophys Res Commun 224:855-862.
20. Ito D, Imai Y, Ohsawa K, Nakajima K, Fukuuchi Y, Kohsaka S. 1998. Microglia-specific localisation of a novel calcium binding protein, Iba1. Brain Res Mol Brain Res 57:1-9.
21. Jordan FL, Thomas WE. 1987. Identification of microglia in primary cultures of mixed cerebral cortical cells. Brain Res Bull 19:153-159.
22. Kreutzberg GW. 1986. Neurobiology of regeneration and degeneration. In: May M, editor. The facial nerve. New York: Thieme. p 75-83.
23. Kreutzberg GW. 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19:312-318.
24. Kurihara T, Nishizawa Y, Takahashi Y, Odani S. 1981. Chemical, immunological and catalytic properties of 2′, 3′-cyclic nucleotide 3′-phosphodiesterase purified from brain white matter. Biochem J 195:153-157.
25. Liva SM, de Vellis J. 2001. IL-5 induces proliferation and activation of microglia via an unknown receptor. Neurochem Res 26:629-637.
26. Lowry OJ, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Polin phenol reagent. J Biol Chem 193:265-275.
27. Maga G, Hubscher U. 2003. Proliferating cell nuclear antigen (PCNA): a dancer with many partners. J Cell Sci 116:3051-3060.
28. Moller JC, Klein MA, Haas S, Jones LL, Kreutzberg GW, Raivich G. 1996. Regulation of thrombospondin in the regenerating mouse facial motor nucleus. Glia 17:121-132.
29. Moran LB, Graeber MB. 2004. The facial nerve axotomy model. Brain Res Rev 44:154-178.
30. Nagata K, Takei N, Nakajima K, Saito H, Kohsaka S. 1993. Microglial conditioned medium promotes survival and development of cultured mesencephalic neurons from embryonic rat brain. J Neurosci Res 34:357-363.
31. Nakajima K, Kohsaka S. 2004. Microglia: neuroprotective and neurotrophic cells in the central nervous system. Curr Drug Targets Cardiovasc Haematol Disord 4:65-84.
32. Nakajima K, Hamanoue M, Shimojo M, Takei N, Kohsaka S. 1989. Characterization of microglia isolated from a primary culture of embryonic rat brain by a simplified method. Biomed Res 10(Suppl 3):411-423.
33. Nakajima K, Imazawa M, Miyamoto K. 1991. Presence of another species of myelin basic protein (MBP) in the developing chick brain. Neurochem Int 18:357-365.
34. Nakajima K, Shimojo M, Hamanoue M, Ishiura S, Sugita H, Kohsaka S. 1992a. Identification of elastase as a secretory protease from cultured rat microglia. J Neurochem 58:1401-1408.
35. Nakajima K, Tsuzaki N, Nagata K, Takemoto N, Kohsaka S. 1992b. Production and secretion of plasminogen in cultured rat brain microglia. FEBS Lett 308:179-182.
36. Nakajima K, Tsuzaki N, Shimojo M, Hamanoue M, Kohsaka S. 1992c. Microglia isolated from rat brain secrete a urokinase-type plasminogen activator. Brain Res 577:285-292.
37. Nakajima K, Nagata K, Hamanoue M, Takemoto N, Kohsaka S. 1993. Microglia-derived elastase produces a low-molecular-weight plasminogen that enhances neunte outgrowth in rat neocortical explant cultures. J Neurochem 61:2155-2163.
38. Nakajima K, Reddington M, Kohsaka S, Kreutzberg GW. 1996. Induction of urokinase-type plasminogen activator in rat facial nucleus by axotomy of the facial nerve. J Neurochem 66:2500-2505.
39. Nakajima K, Honda S, Tohyama Y, Imai Y, Kohsaka S, Kurihara T. 2001. Neurotrophin secretion from cultured microglia. J Neurosci Res 65:322-331.
40. Nakajima K, Tohyama Y, Kohsaka S, Kurihara T. 2002. Ceramide activates microglia to enhance the production/secretion of brain-derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro. J Neurochem 80:697-705.
41. Nakajima K, Tohyama Y, Kurihara T, Kohsaka S. 2005. Axotomy-dependent urokinase induction in the rat facial nucleus: possible stimulation of microglia by neurons. Neurochem Int 46:107-116.
42. Nelson PT, Soma LA, Lavi E. 2002. Microglia in diseases of the central nervous system. Ann Med 34:491-500.
43. Norenberg W, Illes P, Gebicke-Haerter PJ. 1994. Sodium channel in isolated human brain macrophages (microglia). Glia 10:165-172.
44. Raivich G, Gehrmann J, Kreutzberg GW. 1991. Increase of macrophage colony-stimulating factor and granulocyte-macrophage colony-stimulating factor receptors in the regenerating rat facial nucleus. J Neurosci Res 30:682-686.
45. Raivich G, Moreno-Flores MT, Moller JC, Kreutzberg GW. 1994. Inhibition of posttraumatic microglial proliferation in a genetic model of macrophage colony-stimulating factor deficiency in the mouse. Eur J Neurosci 6:1615-1618.
46. Rieske E, Graeber MB, Tetzlaff W, Czlonkowska A, Streit WJ, Kreutzberg GW. 1989. Microglia and microglia-derived brain macrophages in culture: generation from axotomized rat facial nuclei, identification and characterization in vitro. Brain Res 492:1-14.
47. Ringheim GE. 1995. Mitogenic effects of interleukin-5 on microglia. Neurosci Lett 201:131-134.
48. Stoll G, Jander S. 1999. The role of microglia and macrophages in the pathophysiology of the CNS. Prog Neurobiol 58:233-247.
49. Streit WJ, Kreutzberg GW. 1987. Lectin binding by resting and reactive microglia. J Neurocytol 16:249-260.
50. Streit WJ, Graeber MB, Kreutzberg GW. 1989. Peripheral nerve lesion produces increased levels of major histocompatibility complex antigens in the central nervous system. J Neuroimmunol 21:117-123.
51. Suzumura A, Mezitis SG, Gonatas NK, Silberberg DH. 1987. MHC antigen expression on bulk isolated macrophage-microglia from newborn mouse brain: induction of Ia antigen expression by gamma-interferon. J Neuroimmunol 15:263-278.
52. Suzumura A, Sawada M, Itoh Y, Marunouchi T. 1994. Interleukin-4 induces proliferation and activation of microglia but suppresses their induction of class II major histocompatibility complex antigen expression. J Neuroimmunol 53:209-218.
53. Williams K, Bar-Or A, Ulvestad E, Olivier A, Antel JP, Yong VW. 1992. Biology of adult human microglia in culture: comparisons with peripheral blood monocytes and astrocytes. J Neuropathol Exp Neurol 51:538-549.